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随机尿尿酸/肌酐在克拉玛依地区高尿酸血症患者分型诊断中的应用
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作者 王晓妹 罗超 +6 位作者 帖阳 贺勇 杨喜奎 刘雅琳 孙悦 王福刚 何訸 《检验医学》 CAS 2024年第9期859-864,共6页
目的探讨随机尿尿酸/肌酐(UA/Cr)在克拉玛依地区高尿酸血症(HUA)患者分型诊断中的应用价值。方法选取2022年4月—2023年5月克拉玛依市中西医结合医院(市人民医院)HUA患者126例(HUA)组、健康体检者124名(对照组)。检测所有研究对象总胆固... 目的探讨随机尿尿酸/肌酐(UA/Cr)在克拉玛依地区高尿酸血症(HUA)患者分型诊断中的应用价值。方法选取2022年4月—2023年5月克拉玛依市中西医结合医院(市人民医院)HUA患者126例(HUA)组、健康体检者124名(对照组)。检测所有研究对象总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、血清尿素(SU)、血清尿酸(SUA)、血清肌酐(SCr)、尿尿酸(UUA)、尿肌酐(UCr)水平。采用Spearman分析评价HUA组随机尿UA/Cr与24 h尿尿酸排泄量(UUE)和肾脏尿酸排泄分数(FEUA)的相关性。采用受试者工作特征(ROC)曲线评价随机尿UA/Cr判断HUA患者分型的效能。结果HUA组和对照组性别、年龄、TC、HDL-C、SU、肾小球滤过率(eGFR)差异均无统计学意义(P>0.05)。HUA组体重指数、TG、FBG、SUA、SCr均显著高于对照组(P<0.05),HUA组尿pH值显著低于对照组(P<0.05)。肾脏排泄不良型与肾脏负荷过多型UUA、UUE、FEUA、随机尿UA/Cr比较差异均有统计学意义(P<0.05)。肾脏排泄不良型UUA、UUE、随机尿UA/Cr均低于混合型(P<0.05)。HUA组随机尿UA/Cr与UUE、FEUA均呈正相关(r值分别为0.7784、0.7086,P<0.05)。随机尿UA/Cr判断FEUA 5.5%的临界值为0.297,敏感性为92.5%,特异性为64.4%,曲线下面积(AUC)为0.804。随机尿UA/Cr判断HUA UUE≤600 mg·d^(–1)·(1.73m^(2))–1的临界值为0.302,敏感性为87.6%,特异性为100.0%,AUC为0.979。肾脏排泄不良型随机尿UA/Cr分型临界值为<0.297;肾脏负荷过多型随机尿UA/Cr分型临界值为>0.302;其他型随机尿UA/Cr分型临界值为≥0.297且≤0.302;混合型无法依据统计学结果筛选。结论随机尿UA/Cr对克拉玛依地区HUA分型有一定参考价值。 展开更多
关键词 随机尿尿酸/肌酐 高尿酸血症 尿酸排泄量 尿酸排泄分数
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Negative Thermal Expansion and Spontaneous Magnetostriction of Nd2Fe16.5Cr0.5 Compound 被引量:1
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作者 Li-Yu HAO tie yang Ming Tan 《Chinese Physics Letters》 SCIE CAS CSCD 2020年第1期48-50,共3页
The structural,thermal expansion,and magnetic properties of the Nc/2^16.5^0.5 compound are investigated by means of x-ray diffraction and magnetization measurements.The Nd2^616.560.5 compound has a rhombohedral Th2Znn... The structural,thermal expansion,and magnetic properties of the Nc/2^16.5^0.5 compound are investigated by means of x-ray diffraction and magnetization measurements.The Nd2^616.560.5 compound has a rhombohedral Th2Znn-type structure.There exists a small negative thermal expansion resulting from a spontaneous magnetostriction in the magnetic state of the^2^16.5 Cr0.5 compound.The average thermal expansion coefficient is-1.06×10^6/K in a temperature range 299-394 K.The spontaneous magnetostrictive deformation and the Curie temperature are discussed. 展开更多
关键词 structure. DEFORMATION Nd2Fe
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Negative Thermal Expansion of the Dy_2Fe_(16)Cr Compound
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作者 Li-Yu HAO tie yang +1 位作者 Xiao-Tian WANG Ming TAN 《Chinese Physics Letters》 SCIE CAS CSCD 2019年第6期41-43,共3页
Structural, thermal expansion, and magnetic properties of the Dy_2Fe_(16)Cr compound are investigated by means of x-ray diffraction and magnetization measurements. The Dy_2Fe_(16)Cr compound has a hexagonal Th_2Ni_(17... Structural, thermal expansion, and magnetic properties of the Dy_2Fe_(16)Cr compound are investigated by means of x-ray diffraction and magnetization measurements. The Dy_2Fe_(16)Cr compound has a hexagonal Th_2Ni_(17)-type structure. There exists a negative thermal expansion resulting from a strong spontaneous magnetostriction in the magnetic state of the Dy_2Fe_(16)Cr compound. The average thermal expansion coefficient is-0.794 × 10^(-5)/K in the temperature range 292–407 K. The spontaneous magnetostrictive deformation and the Curie temperature are discussed. 展开更多
关键词 NEGATIVE Thermal EXPANSION Dy2Fe16Cr COMPOUND MAGNETIC STATE
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Designing Unpowered Shoulder Complex Exoskeleton via Contralateral Drive for Self-rehabilitation of Post-stroke Hemiparesis
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作者 Ning Li tie yang +6 位作者 yang yang Wenyuan Chen Peng Yu Chuang Zhang Ning Xi Ying Zhao Wenxue Wang 《Journal of Bionic Engineering》 SCIE EI CSCD 2023年第3期992-1007,共16页
Rehabilitation using exoskeleton robots can effectively remediate dysfunction and restore post-stroke survivors’ physical ability. However, low kinematic compatibility and poor self-participation of post-stroke patie... Rehabilitation using exoskeleton robots can effectively remediate dysfunction and restore post-stroke survivors’ physical ability. However, low kinematic compatibility and poor self-participation of post-stroke patients in rehabilitation restrict the outcomes of exoskeleton-based therapy. The study presents an Unpowered Shoulder Complex Exoskeleton (USCE), consisting of Shoulder Girdle Mechanism (SGM), Ball-and-Socket Joint Mechanism (BSM), Gravity Compensating Mechanism (GCM) and Adjustable Alignment Design (AAD), to achieve self-rehabilitation of shoulder via energy transfer from the healthy upper limb to the affected counterpart of post-stroke hemiplegic patients. The SGM and AAD are designed to improve the kinematic compatibility by compensating for displacements of the glenohumeral joint with the adaptable size of USCE for different wearers. The BSM and GCM can transfer the body movement and energy from the healthy half of the body to the affected side without external energy input and enhance the self-participation with sick posture correction. The experimental results show that the USCE can provide high kinematic compatibility with 90.9% movement similarity between human and exoskeleton. Meanwhile, the motion ability of a post-stroke patient’s affected limb can be increased through energy transfer. It is expected that USCE can improve outcomes of home-based self-rehabilitation. 展开更多
关键词 Unpowered exoskeleton Health-paralysis combination Energy transfer Self-rehabilitation Shoulder mechanism design
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Bioinspired Musculoskeletal Model-based Soft Wrist Exoskeleton for Stroke Rehabilitation 被引量:1
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作者 Ning Li tie yang +8 位作者 yang yang Peng Yu Xiujuan Xue Xingang Zhao Guoli Song Imad HElhajj Wenxue Wang Ning Xi Lianqing Liu 《Journal of Bionic Engineering》 SCIE EI CSCD 2020年第6期1163-1174,共12页
Exoskeleton robots have demonstrated the potential to rehabilitate stroke dyskinesia.Unfortunately,poor human-machine physiological coupling causes unexpected damage to human of muscles and joints.Moreover,inferior hu... Exoskeleton robots have demonstrated the potential to rehabilitate stroke dyskinesia.Unfortunately,poor human-machine physiological coupling causes unexpected damage to human of muscles and joints.Moreover,inferior humanoid kinematics control would restrict human natural kinematics.Failing to deal with these problems results in bottlenecks and hinders its application.In this paper,the simplified muscle model and muscle-liked kinematics model were proposed,based on which a soft wrist exoskeleton was established to realize natural human interaction.Firstly,we simplified the redundant muscular system related to the wrist joint from ten muscles to four,so as to realize the human-robot physiological coupling.Then,according to the above human-like musculoskeletal model,the humanoid distributed kinematics control was established to achieve the two DOFs coupling kinematics of the wrist.The results show that the wearer of an exoskeleton could reduce muscle activation and joint force by 43.3%and 35.6%,respectively.Additionally,the humanoid motion trajectories similarity of the robot reached 91.5%.Stroke patients could recover 90.3%of natural motion ability to satisfy for most daily activities.This work provides a fundamental understanding on human-machine physiological coupling and humanoid kinematics control of the exoskeleton robots for reducing the post-stroke complications. 展开更多
关键词 stroke rehabilitation simplified muscle model soft wrist exoskeleton robot bionic kinematics model
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