Subcellular distribution of N-methyl-D-aspartic acid receptor subunit 1 in neural stem cells within subventricular zone of adult rats

The subcellular localization of N-methyI-D-aspartic acid receptor subunit 1 in neural stem cells of the subventricular zone of adult rats was detected using electron microscopy, following immunohistochemistry and immunogold-silver double staining. Results confirmed the presence of neural stem cells in the subventricular zone, which is a key neurogenic region in the central nervous system of adult mammals. The expression of N-methyI-D-aspartic acid receptor subunit 1 was higher than that of nestin and mainly distributed in the cell membrane, cytoplasm, rough endoplasmic reticulum and Golgi complex of neural stem cells.

A study on nuclear analysis of the divertor region of the CFETR

This paper presents the nuclear analysis performance of the Chinese Fusion Engineering Test Reactor(CFETR)divertor region using the MCNP-5 Monte Carlo N-particles code in a 3 D geometry model.We assessed the nuclear responses of the divertor region component systems and evaluated their shielding capability,which can support the development strategy of the physical and engineering design of the CFETR.Model specification based on the latest CAD model of the CFETR divertor has been integrated into the CFETR MCNP reference model with a major/minor radius R=7.2 m/a=2.2 m in the 22.5°model,and a fusion-power range of around 1-1.5 GW.The nuclear heating and radiation damage of the divertor system are enhanced compared to that of the ITER and the earlier CFETR design.The initial nuclear responses of the toroidal field coil and vacuum vessel systems showed that the shielding of the current divertor design is not sufficient and optimization work has been carried out.We also carried out calculations and analysis using a hypothetical operating scenario of over 14 years.An excellent improvement in the nuclear performance has been obtained by the improved additional shielding block in the divertor region when referring to the ITER design limit,which can support the design of the future update of the divertor region systems of the CFETR.

Conceptual design and heat transfer performance of a flat-tile water-cooled divertor target

The divertor target components for the Chinese fusion engineering test reactor(CFETR)and the future experimental advanced superconducting tokamak(EAST)need to remove a heat flux of up to20 MW m-2.In view of such a high heat flux removal requirement,this study proposes a conceptual design for a flat-tile divertor target based on explosive welding and brazing technology.Rectangular water-cooled channels with a special thermal transfer structure(TTS)are designed in the heat sink to improve the flat-tile divertor target’s heat transfer performance(HTP).The parametric design and optimization methods are applied to study the influence of the TTS variation parameters,including height(H),width(W*),thickness(T),and spacing(L),on the HTP.The research results show that the flat-tile divertor target’s HTP is sensitive to the TTS parameter changes,and the sensitivity is T>L>W*>H.The HTP first increases and then decreases with the increase of T,L,and W*and gradually increases with the increase of H.The optimal design parameters are as follows:H=5.5 mm,W*=25.8 mm,T=2.2 mm,and L=9.7 mm.The HTP of the optimized flat-tile divertor target at different flow speeds and tungsten tile thicknesses is studied using the numerical simulation method.A flat-tile divertor mock-up is developed according to the optimized parameters.In addition,high heat flux(HHF)tests are performed on an electron beam facility to further investigate the mock-up HTP.The numerical simulation calculation results show that the optimized flat-tile divertor target has great potential for handling the steady-state heat load of 20 MW m-2under the tungsten tile thickness<5 mm and the flow speed7 m s^(-1).The heat transfer efficiency of the flat-tile divertor target with rectangular cooling channels improves by13%and30%compared to that of the flat-tile divertor target with circular cooling channels and the ITER-like monoblock,respectively.The HHF tests indicate that the flat-tile divertor mock-up can successfully withstand 1000 cycles of20 MW m-2of heat load without visible deformation,damage,and HTP degradation.The surface temperature of the flat-tile divertor mock-up at the 1000th cycle is only930℃.The flat-tile divertor target’s HTP is greatly improved by the parametric design and optimization method,and is better than the ITER-like monoblock and the flat-tile mock-up for the WEST divertor.This conceptual design is currently being applied to the engineering design of the CFETR and EAST flat-tile divertors.