A simple, water-soluble, Fe3+-selective fluorescent probe, derived from rhodamine B, was synthesized and characterized. The probe exhibits a fluorescence response toward Fe3+ with acceptable sensitivity and selectiv...A simple, water-soluble, Fe3+-selective fluorescent probe, derived from rhodamine B, was synthesized and characterized. The probe exhibits a fluorescence response toward Fe3+ with acceptable sensitivity and selectivity and even facilitates visual or naked-eye detection of Fe3+. The experiment results show that the response of the probe to Fe3+ is pH-independent over a wide range of 4.0-10.0. In addition, fluorescence microscopic imaging experiments have proven that the probe is cell permeable and can be used for monitoring intracellular Fe3+ in living cells.展开更多
基金supported by Natural Science Foundation of Fujian Province(No.2013H0019)the Science Foundation of Education Department of Fujian Province(No.JA11064)+1 种基金the Open Foundation of the State Key Laboratory of Fine Chemicals(No.KF1307)the Open Foundation of Ministry of Education Key Laboratory of Synthetic and Natural Functional Molecular Chemistry
文摘A simple, water-soluble, Fe3+-selective fluorescent probe, derived from rhodamine B, was synthesized and characterized. The probe exhibits a fluorescence response toward Fe3+ with acceptable sensitivity and selectivity and even facilitates visual or naked-eye detection of Fe3+. The experiment results show that the response of the probe to Fe3+ is pH-independent over a wide range of 4.0-10.0. In addition, fluorescence microscopic imaging experiments have proven that the probe is cell permeable and can be used for monitoring intracellular Fe3+ in living cells.