Phenolic compounds are a class of hazardous substances for human.To study the antiradical potential of a series of phenolic compounds from the aspect of position and substituent type,phenol,o⁃dihydroxybenzene(ODB),m⁃d...Phenolic compounds are a class of hazardous substances for human.To study the antiradical potential of a series of phenolic compounds from the aspect of position and substituent type,phenol,o⁃dihydroxybenzene(ODB),m⁃dihydroxybenzene(MDB),p⁃dihydroxybenzene(PDB),paranitrophenol(PNP),and o⁃chlorophenol(OCP)were selected as typical targets.In addition,to elucidate the degradation discrepancy of phenolic compounds,quantum chemical calculations(QCCs)were obtained using the B3LYP method along with a 6-311G(d,p)basis set.Calculations indicate that phenol,ODB,MDB,and PDB,with electron⁃donating groups,exhibited high antiradical potential,while PNP and OCP,with electron⁃withdrawing groups,exhibited low antiradical potential.The chemical indices calculations show that para⁃compounds and ortho⁃compounds had high antiradical ability.Moreover,phenol,ODB,MDB,and PDB possessed higher bond dissociation enthalpy(BDE)and lower adiabatic ionization potential(AIP)values compared with those of OCP and PNP.Medium effects,even in vacuo,were also taken into account to reveal the antiradical ability of phenolic compounds.展开更多
目的通过对肠镜检查的大宗病例进行分析研究,指导临床对拟检患者进镜难度预评估与检查前准备。方法回顾性分析2019年4月至2020年4月吉林大学第一医院胃肠内科·内镜中心所建立的普通肠镜检查数据库共586例病例,根据内镜医生检查过...目的通过对肠镜检查的大宗病例进行分析研究,指导临床对拟检患者进镜难度预评估与检查前准备。方法回顾性分析2019年4月至2020年4月吉林大学第一医院胃肠内科·内镜中心所建立的普通肠镜检查数据库共586例病例,根据内镜医生检查过程中对进镜难度的主观评估结果分为E(easy,容易)组与D(difficult,困难)组,对两组间相关临床数据进行对比,并对结肠镜进镜难度相关危险因素包括:主诉是否便秘、口服泻药种类、性别组成、年龄、体质指数(BMI)、既往腹部手术史、进镜时肠道清洁程度进行单因素及多因素分析,进而构建预测结肠镜进镜操作难易程度的列线图模型。结果E组患者与D组患者相比进镜时间更短(10 vs 15 min,P<0.001),需要额外注水来润滑肠道从而降低进镜难度缓解患者疼痛的比例更低(27.7%vs 92.7%,P<0.001),到达回盲部的比例更高(100%vs 96.3%,P<0.001),同时E组患者较D组患者疼痛视觉模糊评分(VAS)更低,痛苦更小(4 vs 5,P<0.001)。单因素分析发现,两组在主诉是否便秘、口服泻药种类、性别组成、年龄、BMI、既往腹部手术史方面存在统计学差异(P均<0.05),而在进镜时肠道准备清洁程度方面无统计学差异(P≥0.05)。进一步行Logistic回归分析结果显示,主诉便秘、BMI低、口服磷酸钠盐口服溶液、腹部手术史是进镜困难的独立危险因素(P均<0.05),综合上述独立危险因素构建了预测结肠镜进镜操作难易程度的列线图模型。结论主诉便秘、BMI低、口服磷酸钠盐口服溶液、腹部手术史是进镜困难的独立危险因素,可利用基于上述独立危险因素构建的列线图模型于检查前预测出受检者肠镜进镜操作的难度,从而指导该结肠镜检查的相关准备。展开更多
Two types of lanthanide coordination polymers, namely, [Ln(PA)(NO_3)(DMA)_3]_n(Ln=Gd(1), Dy(2), Eu(3), Tb(4))(type I), and {[Ln_2(PA)_3(DMF)_4]·2DMF}(Ln=Eu(5), Tb(6))(type II)(PA=Pamoic acid, DMA=dimethylacetamid...Two types of lanthanide coordination polymers, namely, [Ln(PA)(NO_3)(DMA)_3]_n(Ln=Gd(1), Dy(2), Eu(3), Tb(4))(type I), and {[Ln_2(PA)_3(DMF)_4]·2DMF}(Ln=Eu(5), Tb(6))(type II)(PA=Pamoic acid, DMA=dimethylacetamide,DMF=N,N-dimethylformamide), have been synthesized by the reaction of Ln(NO_3)_3·6H_2O with pamoic acid through layer diffusion method. These complexes were characterized by single crystal X-ray diffraction, infrared spectroscopy(IR),thermogravimetric analysis(TGA), fluorescence and magnetic measurements. Solvents and lanthanide atoms in the reaction play an important role in controlling different structures. Type I demonstrated 1-D linear chain structure connected by Ln atoms and PA ligands. Type II exhibited non-interpenetrating 3-D 6-connected 4_36^(12) nets based on binuclear [Ln_2(CO_2)_6(DMF)_4] cores.Magnetic properties of complexes 1–4 were investigated in details. Complex 1 shows significant magnetocaloric effect with–ΔS_m=20.37 J kg^(–1) K^(–1) at 3.0 K and 7 T. Complex 2 exhibits slow relaxation of the magnetization. Complexes 3–6 exhibit both ligand- and metal-centered fluorescent properties. Complex 6 demonstrates fluorescent sensing of DMF and Cu^(2+) ion.展开更多
Summary What is already known about this topic?Salmonella causes acute and chronic diseases in food animals,and infected food animals are one of the most important source of human infection.What does this report contr...Summary What is already known about this topic?Salmonella causes acute and chronic diseases in food animals,and infected food animals are one of the most important source of human infection.What does this report contribute?The prevalence of Salmonella was 10.5%in chicken samples,24.4%in pig,23.3%in duck,and 29.4%in milk.Salmonella isolates were highly resistant to ampicillin(59.60%).What are the implications for public health practices?Data on Salmonella infections among food animals in China could help identify sources and factors related to the spread of Salmonella in food animals and food production chains.展开更多
基金Sponsored by the Open Project of State Key Laboratory of Urban Water Resource and Environment,Harbin Institute of Technology(Grant No.HCK201804).
文摘Phenolic compounds are a class of hazardous substances for human.To study the antiradical potential of a series of phenolic compounds from the aspect of position and substituent type,phenol,o⁃dihydroxybenzene(ODB),m⁃dihydroxybenzene(MDB),p⁃dihydroxybenzene(PDB),paranitrophenol(PNP),and o⁃chlorophenol(OCP)were selected as typical targets.In addition,to elucidate the degradation discrepancy of phenolic compounds,quantum chemical calculations(QCCs)were obtained using the B3LYP method along with a 6-311G(d,p)basis set.Calculations indicate that phenol,ODB,MDB,and PDB,with electron⁃donating groups,exhibited high antiradical potential,while PNP and OCP,with electron⁃withdrawing groups,exhibited low antiradical potential.The chemical indices calculations show that para⁃compounds and ortho⁃compounds had high antiradical ability.Moreover,phenol,ODB,MDB,and PDB possessed higher bond dissociation enthalpy(BDE)and lower adiabatic ionization potential(AIP)values compared with those of OCP and PNP.Medium effects,even in vacuo,were also taken into account to reveal the antiradical ability of phenolic compounds.
文摘目的通过对肠镜检查的大宗病例进行分析研究,指导临床对拟检患者进镜难度预评估与检查前准备。方法回顾性分析2019年4月至2020年4月吉林大学第一医院胃肠内科·内镜中心所建立的普通肠镜检查数据库共586例病例,根据内镜医生检查过程中对进镜难度的主观评估结果分为E(easy,容易)组与D(difficult,困难)组,对两组间相关临床数据进行对比,并对结肠镜进镜难度相关危险因素包括:主诉是否便秘、口服泻药种类、性别组成、年龄、体质指数(BMI)、既往腹部手术史、进镜时肠道清洁程度进行单因素及多因素分析,进而构建预测结肠镜进镜操作难易程度的列线图模型。结果E组患者与D组患者相比进镜时间更短(10 vs 15 min,P<0.001),需要额外注水来润滑肠道从而降低进镜难度缓解患者疼痛的比例更低(27.7%vs 92.7%,P<0.001),到达回盲部的比例更高(100%vs 96.3%,P<0.001),同时E组患者较D组患者疼痛视觉模糊评分(VAS)更低,痛苦更小(4 vs 5,P<0.001)。单因素分析发现,两组在主诉是否便秘、口服泻药种类、性别组成、年龄、BMI、既往腹部手术史方面存在统计学差异(P均<0.05),而在进镜时肠道准备清洁程度方面无统计学差异(P≥0.05)。进一步行Logistic回归分析结果显示,主诉便秘、BMI低、口服磷酸钠盐口服溶液、腹部手术史是进镜困难的独立危险因素(P均<0.05),综合上述独立危险因素构建了预测结肠镜进镜操作难易程度的列线图模型。结论主诉便秘、BMI低、口服磷酸钠盐口服溶液、腹部手术史是进镜困难的独立危险因素,可利用基于上述独立危险因素构建的列线图模型于检查前预测出受检者肠镜进镜操作的难度,从而指导该结肠镜检查的相关准备。
基金Research Basic Ability Enhancement Project of Young and Middle-aged Teachers in Guangxi Universities(Grant No.2019KY0166)the Project of Guangxi University for Nationalities(Grant No.2018MDYB006,2018XJGY46)。
基金supported by the National Natural Science Foundation of China(21571092,21403102)the Natural Science Foundation of Shandong Province(ZR2012BQ023)the University Scientific Research Development Plan of the Education Department of Shandong Province(J14LC10)
文摘Two types of lanthanide coordination polymers, namely, [Ln(PA)(NO_3)(DMA)_3]_n(Ln=Gd(1), Dy(2), Eu(3), Tb(4))(type I), and {[Ln_2(PA)_3(DMF)_4]·2DMF}(Ln=Eu(5), Tb(6))(type II)(PA=Pamoic acid, DMA=dimethylacetamide,DMF=N,N-dimethylformamide), have been synthesized by the reaction of Ln(NO_3)_3·6H_2O with pamoic acid through layer diffusion method. These complexes were characterized by single crystal X-ray diffraction, infrared spectroscopy(IR),thermogravimetric analysis(TGA), fluorescence and magnetic measurements. Solvents and lanthanide atoms in the reaction play an important role in controlling different structures. Type I demonstrated 1-D linear chain structure connected by Ln atoms and PA ligands. Type II exhibited non-interpenetrating 3-D 6-connected 4_36^(12) nets based on binuclear [Ln_2(CO_2)_6(DMF)_4] cores.Magnetic properties of complexes 1–4 were investigated in details. Complex 1 shows significant magnetocaloric effect with–ΔS_m=20.37 J kg^(–1) K^(–1) at 3.0 K and 7 T. Complex 2 exhibits slow relaxation of the magnetization. Complexes 3–6 exhibit both ligand- and metal-centered fluorescent properties. Complex 6 demonstrates fluorescent sensing of DMF and Cu^(2+) ion.
基金The National Key Research andDevelopment Program of China (2016YFD0501301)and National Science Foundation of China(31761133004 and 81861138051).
文摘Summary What is already known about this topic?Salmonella causes acute and chronic diseases in food animals,and infected food animals are one of the most important source of human infection.What does this report contribute?The prevalence of Salmonella was 10.5%in chicken samples,24.4%in pig,23.3%in duck,and 29.4%in milk.Salmonella isolates were highly resistant to ampicillin(59.60%).What are the implications for public health practices?Data on Salmonella infections among food animals in China could help identify sources and factors related to the spread of Salmonella in food animals and food production chains.