The occurrence of obesity has increased across the whole world. Many epidemiological studies have indicated that obesity strongly contributes to the development of cancer, cardiovascular diseases, type 2 diabetes, liv...The occurrence of obesity has increased across the whole world. Many epidemiological studies have indicated that obesity strongly contributes to the development of cancer, cardiovascular diseases, type 2 diabetes, liver diseases and other disorders, accounting for a heavy burden on the public and on health-care systems every year. Excess energy uptake induces adipocyte hypertrophy, hyperplasia and formation of visceral fat in other non-adipose tissues to evoke cardiovascular disease, liver diseases. Adipose tissue can also secrete adipokines and inflammatory cytokines to affect the local microenvironment,induce insulin resistance, hyperglycemia, and activate associated inflammatory signaling pathways. This further exacerbates the development and progression of obesity-associated diseases. Although some progress in the treatment of obesity has been achieved in preclinical and clinical studies, the progression and pathogenesis of obesity-induced diseases are complex and unclear. We still need to understand their links to better guide the treatment of obesity and associated diseases. In this review, we review the links between obesity and other diseases, with a view to improve the future management and treatment of obesity and its co-morbidities.展开更多
A subgroup H of G is called M-supplemented in G if there exists a subgroup B of G such that G = HB and HiB < G for every maximal subgroup Hi of H. In this paper, we use M-suppiemented subgroups to study the structu...A subgroup H of G is called M-supplemented in G if there exists a subgroup B of G such that G = HB and HiB < G for every maximal subgroup Hi of H. In this paper, we use M-suppiemented subgroups to study the structure of finite groups and obtain some new characterization about solvability and p-supersolvability for a fixed prime p. Some results in the literature are corollaries of our theorems.展开更多
基金supported by the Natural Science Foundation of China (No. 82073759, China)Qingdao Postdoctoral Science Foundation (No. 862105040014, China)+1 种基金Special funds of Shandong Province for Qingdao National Laboratory of Marine Science and Technology (No. 2022QNLM030003, China)National Science and Technology Major Project for Significant New Drugs Development (No. 2018ZX09735004, China)。
文摘The occurrence of obesity has increased across the whole world. Many epidemiological studies have indicated that obesity strongly contributes to the development of cancer, cardiovascular diseases, type 2 diabetes, liver diseases and other disorders, accounting for a heavy burden on the public and on health-care systems every year. Excess energy uptake induces adipocyte hypertrophy, hyperplasia and formation of visceral fat in other non-adipose tissues to evoke cardiovascular disease, liver diseases. Adipose tissue can also secrete adipokines and inflammatory cytokines to affect the local microenvironment,induce insulin resistance, hyperglycemia, and activate associated inflammatory signaling pathways. This further exacerbates the development and progression of obesity-associated diseases. Although some progress in the treatment of obesity has been achieved in preclinical and clinical studies, the progression and pathogenesis of obesity-induced diseases are complex and unclear. We still need to understand their links to better guide the treatment of obesity and associated diseases. In this review, we review the links between obesity and other diseases, with a view to improve the future management and treatment of obesity and its co-morbidities.
基金Supported by the NSFC (Grants No. 11871062, 11701223 and 11501235)Natural Science Foundation of Jiangsu Province (Grant No. BK20181451)+1 种基金Key Natural Science Foundation of Anhui Education Commission (Grant No. KJ2017A569)Fundamentai Research Funds of China West Normal University (Grants No. 17E091 and 18B032).
文摘A subgroup H of G is called M-supplemented in G if there exists a subgroup B of G such that G = HB and HiB < G for every maximal subgroup Hi of H. In this paper, we use M-suppiemented subgroups to study the structure of finite groups and obtain some new characterization about solvability and p-supersolvability for a fixed prime p. Some results in the literature are corollaries of our theorems.
