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法国成年人下肢不宁综合征的流行病学调查:一项全国性的INSTANT调查研究
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作者 tison f. Crochard A. +1 位作者 Léger D. 黄媛 《世界核心医学期刊文摘(神经病学分册)》 2005年第11期55-56,共2页
Objective: To evaluate the prevalence, characteristics, and treatment of restless legs syndrome (RLS) in France. Methods: In this population-based survey, face-to-face home interviews were conducted among a random sam... Objective: To evaluate the prevalence, characteristics, and treatment of restless legs syndrome (RLS) in France. Methods: In this population-based survey, face-to-face home interviews were conducted among a random sample of 10,263 French adults. A French translation of the four features defined by the International RLS Study Group in 1995 was used to assess the prevalence of symptoms consistent with a diagnosis of RLS. Data on severity of symptoms and their management were also collected. Results: The 12-month prevalence of RLS symptoms in the French adult population was estimated to be 8.5%(95%CI 8.0%, 9.0%), with a higher prevalence (p < 0.001) observed in women (10.8%) than in men (5.8%). Prevalence increases with age until 64 years and decreases thereafter in both sexes. Half of the identified subjects reported symptoms once a week at least. Symptoms were more severe in subjects reporting symptoms once a week at least compared to subjects with less frequent symptoms. In this group, half of the subjects reported a family history, the age at onset was earlier, and severity of symptoms higher. RLS had been previously diagnosed in only 5.3%of the subjects who reported previous medical diagnosis, and recommended RLS drug treatment was received by 3.4%of the 28.7%currently treated subjects. Conclusions: Restless legs syndrome (RLS) occurred in 10%of women and 5%of men. RLS prevalence decreases after the age of 64. RLS is often underdiagnosed and few subjects receive recommended RLS drug treatment. 展开更多
关键词 下肢不宁综合征 INSTANT 流行病学调查 女性患病率 药物治疗 人群患病率 男性发生 症状严重程度 发病年龄 本项
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低剂量局灶性放疗对Tolosa-Hunt综合征的长期疗效
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作者 foubert-Samier A. Sibon I. +2 位作者 Maire J.-P. tison f. 杜兆江 《世界核心医学期刊文摘(眼科学分册)》 2005年第9期6-6,共1页
Tolosa-Hunt syndrome (THS) is a rare cause of painful ophtalmoplegia due to chronic granulomatous inflammation of the cavernous sinus. While corticoids are the treatment of reference, corticodepentlerace and corticore... Tolosa-Hunt syndrome (THS) is a rare cause of painful ophtalmoplegia due to chronic granulomatous inflammation of the cavernous sinus. While corticoids are the treatment of reference, corticodepentlerace and corticoresistance are frequent, hence radiotherapy has been proposed as an alternative treatment. We report a case of long-term improvement (8 years) of THS after low-dose (20 Gy) radiotherapy in a patient with recurrences and corticodependence. 展开更多
关键词 疼痛性眼肌麻痹 激素依赖性 放射治疗 肉芽肿性炎症 海绵窦
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