Are there any ways to analyze objectively if any good changes happen to the bodies for the patients with acquired edentulous by getting a treatment to recover occlusion? In this study, we focused on interleukin 6 (IL-...Are there any ways to analyze objectively if any good changes happen to the bodies for the patients with acquired edentulous by getting a treatment to recover occlusion? In this study, we focused on interleukin 6 (IL-6) as inflammatory cytokine, cortisol known as a stress related substance and secretory immune globulin A (SIgA) related to immune reaction, and chose 14 patients who had occlusion reconstructed by the immediately loaded dental implants because occlusion contact with maxillary and mandibular dentition was lost caused by edentulous jaws or maxillary and mandibular teeth crossing each other and their jaw position and central occlusion position could not settle, and verified the relationship with changes of patients’ physical and mental states during the 6 months of the treatment and the effect of the immediately loaded implants treatment by using saliva which was non-invasive and easy to sample in biomarkers in saliva. Moreover for female subjects, the changes of facial color tones were measured by using Robo Skin Analyz-er<sup>?</sup>, a digital image analyzer, to measure the condition of their skin. In conclusion, the positive correlation between the amount of IL-6 and cortisol was not admitted. However, it was admitted that IL-6 tended to increase when a systemic change which interrupted curing such as the interruption of fusion of the implant and the bone was observed even though the patient did not notice any particular symptoms and cortisol tended to increase when the patient noticed discomfort and mentioned any events under stress on his or her medical record. Moreover with the skin color analysis by Robo Skin Analyzer?, the possibility that the occlusion treatment by the immediate implant had an effect on physical and psychological health promotion through the acquisition of the masticatory function and the aesthetic recovery was indicated.展开更多
Recently, the interest in oral malodor has been grown and the number of people having trouble with oral malodor is increasing year by year. Generally, as the branch of medicine which deals with patients complaining ab...Recently, the interest in oral malodor has been grown and the number of people having trouble with oral malodor is increasing year by year. Generally, as the branch of medicine which deals with patients complaining about oral malodor, dentistry is mostly chosen. On the current situation, however, the dental office side typically finds it difficult to deal with several kinds of oral malodor which show no improvement even though cavities or periodontal disease is completely cured. Main components to cause oral malodor are volatile sulfur compounds (methyl mercaptan, dimethyl sulfide, hydrogen sulfide);in the present study, therefore, the effect of mouthwash solution containing chlorine dioxide to relieve oral malodor and increase saliva production was tested. The subjects were 92 patients (Control group: 2 males, 3 females, age;30.8 ± 4 years old, Mouthwash group: 28 males, 59 females, age: 36.9 ± 1.3 years old) who visited the hospital complaining about oral malodor. Intraoral gas, exhaled gas, the saliva production at rest, the ability for salivation and the buffering ability of saliva were examined twice, before the subjects used the mouthwash solution every day for one month. The simple chromatography oral chroma, which was insulated from the influence of temperature and humidity and also was able to measure with a high degree of accuracy, was used to measure odor as the device analysis method. The control group did not change in VSCs, saliva production and the buffering ability of saliva. After using mouthwash solution, the concentration of the 3 major components gas of intraoral gas and exhaled gas, i.e. methyl mercaptan, dimethyl sulfide, hydrogen sulfide, were all decreased. As for hydrogen sulfide, intraoral gas (from 225.8 ± 28.1 ppb to 41.1 ± 8.8 ppb) and exhaled gas (from 212.0 ± 50.4 ppb to 34.6 ± 16.6 ppb) was significantly decreased. Also, saliva production at rest (from 1.3 ± 0.1 ml to 1.7 ± 0.1 ml) and the ability to salivate (from 4.5 ± 0.3 ml to 5.1 ± 0.3 ml) were both significantly increased. As for the buffering ability of saliva, significant changes were not detected on the change of salivary pH after using mouthwash solution, and it did not have any effects on the buffering ability of saliva. In conclusion, these results suggest that the mouthwash solution containing chlorine dioxide has significant effects on inhibiting malodor.展开更多
It is well-known that odor has a good influence on a human mind and body. In this study, we investigated the effect of the essential oil inhalation of Cyperi rhizoma and Perillae herba which were main aromatic herbs i...It is well-known that odor has a good influence on a human mind and body. In this study, we investigated the effect of the essential oil inhalation of Cyperi rhizoma and Perillae herba which were main aromatic herbs ingredient of the Kososan, to psychological condition, autonomic nerve activity and salivary biomarker. In addition, we examined influence by the favorite difference in odor. 25 healthy female volunteers (control group: 5 people;Cyperi rhizoma group: 10 people;Perillae herba group: 10 people) were examined. POMS was examined at PRE and POST the experiment. Pulse analyser was examined and saliva samples were collected before the inhalation, just after the inhalation, 10 minutes and 20 minutes later, respectively. Saliva samples analyzed for levels of α-amylase and cortisol. At the examination for POMS after the experiment, the preference for the odor was confirmed. About both Cyperi rhizoma and Perillae herba, by the essential oil inhalation, mental stability and relaxation effect were provided in psychological and psysiological evaluation. In the “like” group, relaxation was greater than “unlike” group. However, about Cyperi rhizoma, the stress was relaxed regardless of the favorite difference in odor, and a physical relaxation effect was shown. In addition, about the autonomic nerve activity, the parasympathetic nerve was not activated, and it was suggested that it was made and stabilized the balance of the autonomic nerve.展开更多
文摘Are there any ways to analyze objectively if any good changes happen to the bodies for the patients with acquired edentulous by getting a treatment to recover occlusion? In this study, we focused on interleukin 6 (IL-6) as inflammatory cytokine, cortisol known as a stress related substance and secretory immune globulin A (SIgA) related to immune reaction, and chose 14 patients who had occlusion reconstructed by the immediately loaded dental implants because occlusion contact with maxillary and mandibular dentition was lost caused by edentulous jaws or maxillary and mandibular teeth crossing each other and their jaw position and central occlusion position could not settle, and verified the relationship with changes of patients’ physical and mental states during the 6 months of the treatment and the effect of the immediately loaded implants treatment by using saliva which was non-invasive and easy to sample in biomarkers in saliva. Moreover for female subjects, the changes of facial color tones were measured by using Robo Skin Analyz-er<sup>?</sup>, a digital image analyzer, to measure the condition of their skin. In conclusion, the positive correlation between the amount of IL-6 and cortisol was not admitted. However, it was admitted that IL-6 tended to increase when a systemic change which interrupted curing such as the interruption of fusion of the implant and the bone was observed even though the patient did not notice any particular symptoms and cortisol tended to increase when the patient noticed discomfort and mentioned any events under stress on his or her medical record. Moreover with the skin color analysis by Robo Skin Analyzer?, the possibility that the occlusion treatment by the immediate implant had an effect on physical and psychological health promotion through the acquisition of the masticatory function and the aesthetic recovery was indicated.
文摘Recently, the interest in oral malodor has been grown and the number of people having trouble with oral malodor is increasing year by year. Generally, as the branch of medicine which deals with patients complaining about oral malodor, dentistry is mostly chosen. On the current situation, however, the dental office side typically finds it difficult to deal with several kinds of oral malodor which show no improvement even though cavities or periodontal disease is completely cured. Main components to cause oral malodor are volatile sulfur compounds (methyl mercaptan, dimethyl sulfide, hydrogen sulfide);in the present study, therefore, the effect of mouthwash solution containing chlorine dioxide to relieve oral malodor and increase saliva production was tested. The subjects were 92 patients (Control group: 2 males, 3 females, age;30.8 ± 4 years old, Mouthwash group: 28 males, 59 females, age: 36.9 ± 1.3 years old) who visited the hospital complaining about oral malodor. Intraoral gas, exhaled gas, the saliva production at rest, the ability for salivation and the buffering ability of saliva were examined twice, before the subjects used the mouthwash solution every day for one month. The simple chromatography oral chroma, which was insulated from the influence of temperature and humidity and also was able to measure with a high degree of accuracy, was used to measure odor as the device analysis method. The control group did not change in VSCs, saliva production and the buffering ability of saliva. After using mouthwash solution, the concentration of the 3 major components gas of intraoral gas and exhaled gas, i.e. methyl mercaptan, dimethyl sulfide, hydrogen sulfide, were all decreased. As for hydrogen sulfide, intraoral gas (from 225.8 ± 28.1 ppb to 41.1 ± 8.8 ppb) and exhaled gas (from 212.0 ± 50.4 ppb to 34.6 ± 16.6 ppb) was significantly decreased. Also, saliva production at rest (from 1.3 ± 0.1 ml to 1.7 ± 0.1 ml) and the ability to salivate (from 4.5 ± 0.3 ml to 5.1 ± 0.3 ml) were both significantly increased. As for the buffering ability of saliva, significant changes were not detected on the change of salivary pH after using mouthwash solution, and it did not have any effects on the buffering ability of saliva. In conclusion, these results suggest that the mouthwash solution containing chlorine dioxide has significant effects on inhibiting malodor.
文摘It is well-known that odor has a good influence on a human mind and body. In this study, we investigated the effect of the essential oil inhalation of Cyperi rhizoma and Perillae herba which were main aromatic herbs ingredient of the Kososan, to psychological condition, autonomic nerve activity and salivary biomarker. In addition, we examined influence by the favorite difference in odor. 25 healthy female volunteers (control group: 5 people;Cyperi rhizoma group: 10 people;Perillae herba group: 10 people) were examined. POMS was examined at PRE and POST the experiment. Pulse analyser was examined and saliva samples were collected before the inhalation, just after the inhalation, 10 minutes and 20 minutes later, respectively. Saliva samples analyzed for levels of α-amylase and cortisol. At the examination for POMS after the experiment, the preference for the odor was confirmed. About both Cyperi rhizoma and Perillae herba, by the essential oil inhalation, mental stability and relaxation effect were provided in psychological and psysiological evaluation. In the “like” group, relaxation was greater than “unlike” group. However, about Cyperi rhizoma, the stress was relaxed regardless of the favorite difference in odor, and a physical relaxation effect was shown. In addition, about the autonomic nerve activity, the parasympathetic nerve was not activated, and it was suggested that it was made and stabilized the balance of the autonomic nerve.
