In this study cortisol and cyclophosphamide were injected into abdominal cavities of mice to keep them in an immunosuppressive state. Then the pathogen Klebsiella pneumoniae was given to infect the lungs and the exper...In this study cortisol and cyclophosphamide were injected into abdominal cavities of mice to keep them in an immunosuppressive state. Then the pathogen Klebsiella pneumoniae was given to infect the lungs and the experimental modcl of lobular pneumonia in the mice was thus established successfully.The experimental animal model has typical pathologic manifestation and good replication and can be used to to study the effect of drugs.展开更多
文摘In this study cortisol and cyclophosphamide were injected into abdominal cavities of mice to keep them in an immunosuppressive state. Then the pathogen Klebsiella pneumoniae was given to infect the lungs and the experimental modcl of lobular pneumonia in the mice was thus established successfully.The experimental animal model has typical pathologic manifestation and good replication and can be used to to study the effect of drugs.
