Background:Coronavirus disease 2019 is still spreading all over the world and without any specific medicine.Traditional Chinese medicine has played an important role in the control of epidemics in China and accumulate...Background:Coronavirus disease 2019 is still spreading all over the world and without any specific medicine.Traditional Chinese medicine has played an important role in the control of epidemics in China and accumulated many experiences.The aim of this study is to summarize the law of traditional Chinese medicine and provide reference for coronavirus disease 2019 traditional Chinese medicine treatment.Methods:We collected the treatment plans of traditional Chinese medicine for coronavirus disease 2019 in 24 provinces of China to evaluate the basic Chinese medicine formulas,and the efficacy types,frequency,“Four Characters”,“Five Tastes”,“Channel Tropism”of herbal medicines.Combination rules between medicines were calculated by Apriori algorithm and Clementine12.0.Results:The formulas for“Relieving Exterior Syndrome”,“Expelling Dampness”,“Clearing Heat”and“Supplementing”have highest proportion.In prevention period and medical observation period,the medicines mainly have effect for“Clearing Heat”,“Relieving Exterior Syndrome”and“Supplementing”.In treatment period,medicines for“Clearing Heat”,“Relieving Superficies”and“Relieving Dampness”had higher frequency.The“Four Characters”of Chinese medicines in all treatment plans were mainly“Cold”and“Warm”.Medicines in the treatment plans always belong to“Pungent Taste”,“Bitter Taste”and“Sweet Taste”.For“Channel Tropism”,most medicines turned over to the“Lung”,“Stoma”and“Spleen”.The common medicine combinations in the recommended formulas during the prevention period and medical observation period were medicines for“Qi-Supplementing”and“Relieving Superficies”.In treatment period(mild,moderate,severe/critical),medicines for“Dampness Expelling”,“Relieving Superficies”and“Qi-Supplementing”were combined in a high frequency.In recovery period,the medicines for“Dispelling Dampness”combined the medicines for“Promoting Blood Circulation”with highest frequency.Conclusions:We found the characteristics of medicine and prescription rules of traditional Chinese medicine for the treatment of coronavirus disease 2019 and provided scientificity and effectiveness of it.More importantly,it provides reference for the development of new clinical prescriptions for coronavirus disease 2019.展开更多
Clustering is an unsupervised learning technology,and it groups information(observations or datasets)according to similarity measures.Developing clustering algorithms is a hot topic in recent years,and this area devel...Clustering is an unsupervised learning technology,and it groups information(observations or datasets)according to similarity measures.Developing clustering algorithms is a hot topic in recent years,and this area develops rapidly with the increasing complexity of data and the volume of datasets.In this paper,the concept of clustering is introduced,and the clustering technologies are analyzed from traditional and modern perspectives.First,this paper summarizes the principles,advantages,and disadvantages of 20 traditional clustering algorithms and 4 modern algorithms.Then,the core elements of clustering are presented,such as similarity measures and evaluation index.Considering that data processing is often applied in vehicle engineering,finally,some specific applications of clustering algorithms in vehicles are listed and the future development of clustering in the era of big data is highlighted.The purpose of this review is to make a comprehensive survey that helps readers learn various clustering algorithms and choose the appropriate methods to use,especially in vehicles.展开更多
The surface properties of biomaterials are the key factors for the success of artificial implants in the body.The creation of patterns on titanium alloys by laser surface texturing techniques can modify the surface to...The surface properties of biomaterials are the key factors for the success of artificial implants in the body.The creation of patterns on titanium alloys by laser surface texturing techniques can modify the surface to make it multifunctional.The evolution of the surface morphology of Ti6Al4V alloy textured by a nanosecond laser with 1064 nm wavelength in the air is studied.Laser surface texturing treatment is performed on the titanium alloy through different pulse numbers,power,pulse width and scan times to obtain different morphologies.The 2D cross-section profile shows that the morphology can be divided into three types in the evolution process of various pulse numbers,powers and pulse widths:bump-shaped,hump-shaped and crater-shaped.It is found that the effect of pulse width on morphology mainly depends on power.The effects of laser parameters on the height of bumps and the evolution of morphology are the main research points to analyse the topography evolution.The causes of bumps are also analysed.Energy dispersive spectrometer measures the area irradiated by the laser,and it is found that the oxygen content of the bump is up to 43.1%,which can speculate that the bump is the result of the oxidation reaction.展开更多
Laser surface texturing(LST)is a non-contact manufacturing process for fabricating functional surfaces in a manner that improves the corresponding wettability,and is widely used in biomedicine and industry.Laser surfa...Laser surface texturing(LST)is a non-contact manufacturing process for fabricating functional surfaces in a manner that improves the corresponding wettability,and is widely used in biomedicine and industry.Laser surface texturing is a facile approach that is compatible with various materials,can result in a hierarchical texture,and enables a high degree of surface wetting(i.e.,extreme wetting).In addition to surface structures,surface chemical modification is a primary factor in producing extreme wetting surfaces.This review discusses the effects of various surface textures and surface chemistries on wettability.Optimal laser parameters for the desired surface texture are based on the fundamental wettability and laser mechanism.In particular,bumps in the morphology are conducive to obtaining extreme wetting.Diverse surface chemical strategies result in extreme wetting by different mechanisms.This paper makes a rigorous evaluation of the laser parameters and optimal surface chemical modifications by elucidating the relationships between the surface structure,surface chemical modification,and wettability,and in so doing,determines the final wettability.The unresolved problems of LST are presented in the conclusion.This review provides guidance,development directions,and an integrated framework for LST,which will be useful for fabricating extreme wetting surfaces on various metals.展开更多
The diagenetic evolution of the moldic-pore-containing gypsum dolomites of the Middle Ordovician Majiagou Formation in the eastern Ordos Basin,central China,was studied by means of petrological,mineralogical,and geoch...The diagenetic evolution of the moldic-pore-containing gypsum dolomites of the Middle Ordovician Majiagou Formation in the eastern Ordos Basin,central China,was studied by means of petrological,mineralogical,and geochemical analyses,to improve our understanding of heterogeneity in high-quality reservoirs.The aim of the study was to elucidate the processes that resulted in reservoir tightness and the formation of sweet spots,to guide future exploration.Results show that the moldic-pore-containing gypsum dolomites are the most favorable reservoir in the study area,with a mean porosity of 4.96%and a mean permeability of 0.748 mD.The development and preservation of gypsum moldic pores were the main factors causing reservoir heterogeneity.Specifically,moldic pore development was controlled by the sedimentary microfacies,whereas pore preservation was related to dissolution and filling during telogenetic diagenesis.There were three main dissolution-filling stages that took place in three settings:penecontemporaneous,epigenetic,and burial.These processes controlled the formation of reservoir sweet spots.Early-consolidated dolomite deposits were frequently exposed to the atmosphere in the penecontemporaneous environment under the influence of high-frequency sedimentary cycles,which led to the dissolution of evaporite minerals and consequent formation of gypsum moldic pores,accompanied by infilling by freshwater calcite.During epigenesis,the porosity initially increased due to karstification,then significantly decreased because of calcite infilling resulting from long subaerial exposure(120 Myr),which contributed to reservoir heterogeneity.Finally,during burial the high-temperature and high-pressure conditions led to chemical compaction and continuous tightening of the reservoir,although some burial dissolution also took place.In conclusion,the variable paleo-topography resulted in differences in the intensity of pore filling among the blocks in the study area,resulting in reservoir heterogeneity.展开更多
Accurate perception of the performance degradation of fuel cell is very important to detect its health state.However,inconsistent operating conditions of fuel cell vehicles in the test result in errors in the data.In ...Accurate perception of the performance degradation of fuel cell is very important to detect its health state.However,inconsistent operating conditions of fuel cell vehicles in the test result in errors in the data.In order to obtain a more credible degradation rate,this study proposes a novel method to classify the experimental data collected under different working conditions into similar operating conditions by using dimensionality reduction and clustering algorithms.Firstly,the experimental data collected from fuel cell vehicles belong to high-dimensional data.Then projecting high-dimensional data into three-dimensional feature vector space via principal component analysis(PCA).The dimension-reduced three-dimensional feature vectors are input into the clustering algorithm,such as K-means and density-based noise application spatial clustering(DBSCAN).According to the clustering results,the fuel cell voltage data with similar operating conditions can be classified.Finally,the selected voltage data can be used to precisely represent the true performance degradation of an on-board fuel cell stack.The results show that the voltage using the K-means algorithm declines the fastest,followed by the DBSCAN algorithm, finally the original data, which indicates that the performance of the fuel cell actually declines faste. Early intervention can prolong its life to the greatest extent.展开更多
基金This study was funded by the National Natural Science Foundation of China(No.81403040)Key Programs in Sichuan Department of Science and Technology(20ZDYF2376)Achievement Transformation Project of Chengdu Medical College(CYCG18-06).
文摘Background:Coronavirus disease 2019 is still spreading all over the world and without any specific medicine.Traditional Chinese medicine has played an important role in the control of epidemics in China and accumulated many experiences.The aim of this study is to summarize the law of traditional Chinese medicine and provide reference for coronavirus disease 2019 traditional Chinese medicine treatment.Methods:We collected the treatment plans of traditional Chinese medicine for coronavirus disease 2019 in 24 provinces of China to evaluate the basic Chinese medicine formulas,and the efficacy types,frequency,“Four Characters”,“Five Tastes”,“Channel Tropism”of herbal medicines.Combination rules between medicines were calculated by Apriori algorithm and Clementine12.0.Results:The formulas for“Relieving Exterior Syndrome”,“Expelling Dampness”,“Clearing Heat”and“Supplementing”have highest proportion.In prevention period and medical observation period,the medicines mainly have effect for“Clearing Heat”,“Relieving Exterior Syndrome”and“Supplementing”.In treatment period,medicines for“Clearing Heat”,“Relieving Superficies”and“Relieving Dampness”had higher frequency.The“Four Characters”of Chinese medicines in all treatment plans were mainly“Cold”and“Warm”.Medicines in the treatment plans always belong to“Pungent Taste”,“Bitter Taste”and“Sweet Taste”.For“Channel Tropism”,most medicines turned over to the“Lung”,“Stoma”and“Spleen”.The common medicine combinations in the recommended formulas during the prevention period and medical observation period were medicines for“Qi-Supplementing”and“Relieving Superficies”.In treatment period(mild,moderate,severe/critical),medicines for“Dampness Expelling”,“Relieving Superficies”and“Qi-Supplementing”were combined in a high frequency.In recovery period,the medicines for“Dispelling Dampness”combined the medicines for“Promoting Blood Circulation”with highest frequency.Conclusions:We found the characteristics of medicine and prescription rules of traditional Chinese medicine for the treatment of coronavirus disease 2019 and provided scientificity and effectiveness of it.More importantly,it provides reference for the development of new clinical prescriptions for coronavirus disease 2019.
基金supported in part by the founding of the State Key Laboratory of Industrial Control Technology,Zhejiang University(ICT2021B19)the Technological Innovation and Application Demonstration in Chongqing(Major Themes of Industry:cstc2019jscx-zdztzxX0033,cstc2019jscx-fxyd0158).
文摘Clustering is an unsupervised learning technology,and it groups information(observations or datasets)according to similarity measures.Developing clustering algorithms is a hot topic in recent years,and this area develops rapidly with the increasing complexity of data and the volume of datasets.In this paper,the concept of clustering is introduced,and the clustering technologies are analyzed from traditional and modern perspectives.First,this paper summarizes the principles,advantages,and disadvantages of 20 traditional clustering algorithms and 4 modern algorithms.Then,the core elements of clustering are presented,such as similarity measures and evaluation index.Considering that data processing is often applied in vehicle engineering,finally,some specific applications of clustering algorithms in vehicles are listed and the future development of clustering in the era of big data is highlighted.The purpose of this review is to make a comprehensive survey that helps readers learn various clustering algorithms and choose the appropriate methods to use,especially in vehicles.
基金Natural Science Foundation of Chongqing,Grant/Award Number:No.cstc2019jcyj-msxmX0114。
文摘The surface properties of biomaterials are the key factors for the success of artificial implants in the body.The creation of patterns on titanium alloys by laser surface texturing techniques can modify the surface to make it multifunctional.The evolution of the surface morphology of Ti6Al4V alloy textured by a nanosecond laser with 1064 nm wavelength in the air is studied.Laser surface texturing treatment is performed on the titanium alloy through different pulse numbers,power,pulse width and scan times to obtain different morphologies.The 2D cross-section profile shows that the morphology can be divided into three types in the evolution process of various pulse numbers,powers and pulse widths:bump-shaped,hump-shaped and crater-shaped.It is found that the effect of pulse width on morphology mainly depends on power.The effects of laser parameters on the height of bumps and the evolution of morphology are the main research points to analyse the topography evolution.The causes of bumps are also analysed.Energy dispersive spectrometer measures the area irradiated by the laser,and it is found that the oxygen content of the bump is up to 43.1%,which can speculate that the bump is the result of the oxidation reaction.
基金supported by Natural Science Foundation of Chongqing,China(Grant No.cstc2019jcyj-msxmX0114).
文摘Laser surface texturing(LST)is a non-contact manufacturing process for fabricating functional surfaces in a manner that improves the corresponding wettability,and is widely used in biomedicine and industry.Laser surface texturing is a facile approach that is compatible with various materials,can result in a hierarchical texture,and enables a high degree of surface wetting(i.e.,extreme wetting).In addition to surface structures,surface chemical modification is a primary factor in producing extreme wetting surfaces.This review discusses the effects of various surface textures and surface chemistries on wettability.Optimal laser parameters for the desired surface texture are based on the fundamental wettability and laser mechanism.In particular,bumps in the morphology are conducive to obtaining extreme wetting.Diverse surface chemical strategies result in extreme wetting by different mechanisms.This paper makes a rigorous evaluation of the laser parameters and optimal surface chemical modifications by elucidating the relationships between the surface structure,surface chemical modification,and wettability,and in so doing,determines the final wettability.The unresolved problems of LST are presented in the conclusion.This review provides guidance,development directions,and an integrated framework for LST,which will be useful for fabricating extreme wetting surfaces on various metals.
基金This study was supported by China's National Science&Technology Major Project(Grant No.2016ZX05004006-001-001)CNPC Major Research Project(Research and Application on Key Technologies for Sustainable and High-efficiency Production of 50 Millions tons of Oil&Gas in the Changqing Oilfield,Grant No.2016E-0502).
文摘The diagenetic evolution of the moldic-pore-containing gypsum dolomites of the Middle Ordovician Majiagou Formation in the eastern Ordos Basin,central China,was studied by means of petrological,mineralogical,and geochemical analyses,to improve our understanding of heterogeneity in high-quality reservoirs.The aim of the study was to elucidate the processes that resulted in reservoir tightness and the formation of sweet spots,to guide future exploration.Results show that the moldic-pore-containing gypsum dolomites are the most favorable reservoir in the study area,with a mean porosity of 4.96%and a mean permeability of 0.748 mD.The development and preservation of gypsum moldic pores were the main factors causing reservoir heterogeneity.Specifically,moldic pore development was controlled by the sedimentary microfacies,whereas pore preservation was related to dissolution and filling during telogenetic diagenesis.There were three main dissolution-filling stages that took place in three settings:penecontemporaneous,epigenetic,and burial.These processes controlled the formation of reservoir sweet spots.Early-consolidated dolomite deposits were frequently exposed to the atmosphere in the penecontemporaneous environment under the influence of high-frequency sedimentary cycles,which led to the dissolution of evaporite minerals and consequent formation of gypsum moldic pores,accompanied by infilling by freshwater calcite.During epigenesis,the porosity initially increased due to karstification,then significantly decreased because of calcite infilling resulting from long subaerial exposure(120 Myr),which contributed to reservoir heterogeneity.Finally,during burial the high-temperature and high-pressure conditions led to chemical compaction and continuous tightening of the reservoir,although some burial dissolution also took place.In conclusion,the variable paleo-topography resulted in differences in the intensity of pore filling among the blocks in the study area,resulting in reservoir heterogeneity.
基金supported by the special key project of Chongqing technological innovation and application development(cstc2019jscx-zdztzxX0033)the national key R&D plan of the Ministry of science and Technology(sub project)(2018YFB0105400)the National Natural Science Foundation of China(21908142).
文摘Accurate perception of the performance degradation of fuel cell is very important to detect its health state.However,inconsistent operating conditions of fuel cell vehicles in the test result in errors in the data.In order to obtain a more credible degradation rate,this study proposes a novel method to classify the experimental data collected under different working conditions into similar operating conditions by using dimensionality reduction and clustering algorithms.Firstly,the experimental data collected from fuel cell vehicles belong to high-dimensional data.Then projecting high-dimensional data into three-dimensional feature vector space via principal component analysis(PCA).The dimension-reduced three-dimensional feature vectors are input into the clustering algorithm,such as K-means and density-based noise application spatial clustering(DBSCAN).According to the clustering results,the fuel cell voltage data with similar operating conditions can be classified.Finally,the selected voltage data can be used to precisely represent the true performance degradation of an on-board fuel cell stack.The results show that the voltage using the K-means algorithm declines the fastest,followed by the DBSCAN algorithm, finally the original data, which indicates that the performance of the fuel cell actually declines faste. Early intervention can prolong its life to the greatest extent.