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Novel approaches for posterior segment ocular drug delivery with folate-modified liposomal formulation 被引量:1
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作者 toshiki hayashi Risako Onodera +1 位作者 Kohei Tahara Hirofumi Takeuchi 《Asian Journal of Pharmaceutical Sciences》 SCIE CAS 2016年第1期201-202,共2页
The leading causes of vision impairment and blindness are posterior segment-related diseases including age-related macular degeneration,diabetic macular edema and endophthalmitis.Recently,pharmaceutical approaches to ... The leading causes of vision impairment and blindness are posterior segment-related diseases including age-related macular degeneration,diabetic macular edema and endophthalmitis.Recently,pharmaceutical approaches to these diseases have used steroids and oligonucleotides.These drugs are usually administered via invasive injection because noninvasive delivery method such as eye drop administration of drugs is not available.However,repeated injections are associated with potential risks of complications.Moreover,patients may not comply with such regimens. 展开更多
关键词 LIPOSOME RETINA Eyedrop Active TARGETING
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