Reticular erythematous mucinosis(REM)is a rare,primary cutaneous mucinosis clinically characterized by a persistent reticular erythema on the mid chest and mid-upper back,and histologically by a mononuclear cell infil...Reticular erythematous mucinosis(REM)is a rare,primary cutaneous mucinosis clinically characterized by a persistent reticular erythema on the mid chest and mid-upper back,and histologically by a mononuclear cell infiltrate and deposits of mucin in the dermis.To our knowledge,the present report of REM occurring in a Caucasian man and his sister is the first reported case of familial REM.Since a host-specific immune response to unknown antigens may be involved in the pathogenesis of this entity,human leukocyte antigen typing was determined and compared to those reported in autoimmune diseases.展开更多
文摘Reticular erythematous mucinosis(REM)is a rare,primary cutaneous mucinosis clinically characterized by a persistent reticular erythema on the mid chest and mid-upper back,and histologically by a mononuclear cell infiltrate and deposits of mucin in the dermis.To our knowledge,the present report of REM occurring in a Caucasian man and his sister is the first reported case of familial REM.Since a host-specific immune response to unknown antigens may be involved in the pathogenesis of this entity,human leukocyte antigen typing was determined and compared to those reported in autoimmune diseases.
