Background and purpose: Prestroke dementia is frequent but usually not identified. Non-valvular atrial fibrillation (NVAF)is independently associated with an increased risk for dementia. However, the frequency and det...Background and purpose: Prestroke dementia is frequent but usually not identified. Non-valvular atrial fibrillation (NVAF)is independently associated with an increased risk for dementia. However, the frequency and determinants of prestroke dementia in patients with NVAF have never been evaluated. Objective: The aim of this study was to determine the frequency of prestroke dementia and associated factors in patients with a previously known NVAF. Methods: This is an ancillary study of Stroke in Atrial Fibrillation Ensemble II (SAFE II), an observational study conducted in patients with a previously known NVAF, consecutively admitted for an acute stroke in French and Italian centers. Prestroke dementia was evaluated by the IQCODE in patients with a reliable informant. Patients were considered as demented before stroke when their IQCODE score was ≥ 104. Results: of 204 patients, 39 (19.1 % ; 95 % confidence interval [CI]: 13.7 % - 24.5 % ) patients met criteria for prestroke dementia. The only variable independently associated with prestroke dementia was increasing age (adjusted odds ratio for 1 year increase in age: 1.10; 95 % CI: 1.04- 1.17), and there was a non-significant tendency for previous ischemic stroke or TIA and arterial hypertension. Conclusion: One fifth of stroke patients with a previously known NVAF were already demented before stroke. The main determinant of prestroke dementia is increasing age. A large cohort is necessary to identify other determinants.展开更多
Introduction. The consequences of lightning injuries on the peripheral nervou s system are widely unknown. Case report. We report on a 31 year-old woman who developed a bilateral brachial plexopathy 15 days after a li...Introduction. The consequences of lightning injuries on the peripheral nervou s system are widely unknown. Case report. We report on a 31 year-old woman who developed a bilateral brachial plexopathy 15 days after a lightning strike. The patient recovered progressively. Conclusion. Peripheral neuropathies due to lig htning strikes are probably unrecognized in most of the cases, because occurrenc e may be delayed and only few patients were adequately investigated. Pathophysio logical hypotheses are unclear and lean on experimental studies using electrical current.展开更多
文摘Background and purpose: Prestroke dementia is frequent but usually not identified. Non-valvular atrial fibrillation (NVAF)is independently associated with an increased risk for dementia. However, the frequency and determinants of prestroke dementia in patients with NVAF have never been evaluated. Objective: The aim of this study was to determine the frequency of prestroke dementia and associated factors in patients with a previously known NVAF. Methods: This is an ancillary study of Stroke in Atrial Fibrillation Ensemble II (SAFE II), an observational study conducted in patients with a previously known NVAF, consecutively admitted for an acute stroke in French and Italian centers. Prestroke dementia was evaluated by the IQCODE in patients with a reliable informant. Patients were considered as demented before stroke when their IQCODE score was ≥ 104. Results: of 204 patients, 39 (19.1 % ; 95 % confidence interval [CI]: 13.7 % - 24.5 % ) patients met criteria for prestroke dementia. The only variable independently associated with prestroke dementia was increasing age (adjusted odds ratio for 1 year increase in age: 1.10; 95 % CI: 1.04- 1.17), and there was a non-significant tendency for previous ischemic stroke or TIA and arterial hypertension. Conclusion: One fifth of stroke patients with a previously known NVAF were already demented before stroke. The main determinant of prestroke dementia is increasing age. A large cohort is necessary to identify other determinants.
文摘Introduction. The consequences of lightning injuries on the peripheral nervou s system are widely unknown. Case report. We report on a 31 year-old woman who developed a bilateral brachial plexopathy 15 days after a lightning strike. The patient recovered progressively. Conclusion. Peripheral neuropathies due to lig htning strikes are probably unrecognized in most of the cases, because occurrenc e may be delayed and only few patients were adequately investigated. Pathophysio logical hypotheses are unclear and lean on experimental studies using electrical current.
