AIM:To investigate the role of growth hormone(GH),hyperbaric oxygen therapy(HBOT) and combined therapy on the intestinal neomucosa formation of the gastric serosa.METHODS:Forty-eight male Wistar-albino rats,weighing 2...AIM:To investigate the role of growth hormone(GH),hyperbaric oxygen therapy(HBOT) and combined therapy on the intestinal neomucosa formation of the gastric serosa.METHODS:Forty-eight male Wistar-albino rats,weighing 250-280 g,were used in this study.The rats were divided into four groups(n = 12):Group 1,control,gastric serosal patch;Group 2,gastric serosal patch + GH;Group 3,gastric serosal patch + HBOT;and Group 4,gastric serosal patch + GH + HBOT.Abdominal access was achieved through a midline incision,and after the 1-cm-long defect was created in the jejunum,a 1 cm × 1 cm patch of the gastric corpus was anastomosed to the jejunal defect.Venous blood samples were taken to determine the insulin-like growth factor 1(IGF-1) and insulin-like growth factor binding protein 3(IGFBP-3) basal levels.HBOT was performed in Groups 3 and 4.In Groups 2 and 4,human GH was given subcutaneously at a dose of 2 mg per kg/d for 28 d,beginning on the operation day.All animals were sacrificed 60 d after surgery.The jejunal segment and the gastric anastomotic area were excised for histological examination.The inflammatory process,granulation,collagen deposition and fibroblast activity at the neomucosa formation were studied and scored.Additionally,the villus density,villus height,and crypt depth were counted and recorded.The measurements of villus height and crypt depth were calculated with an ocular micrometer.New vessel growth was determined by calculatingeach new vessel in a 1 mm 2 area.RESULTS:In the histological comparison of groups,no significant differences were observed between the control group and Groups 2 and 3 with respect to epithelialization,granulation,fibroblastic activity and the inflammatory process,but significant differences were present between the control group and all others groups(Groups 2-4) with respect to angiogenesis(P < 0.01) and collagen deposition(P < 0.05,P < 0.01).Significant differences between the control group and Group 4 were also observed with respect to epithelialization and fibroblastic activity(P < 0.01 and P < 0.05,respectively).There were significant differences in villus density in all of groups compared with the control group(P < 0.05).Crypt depth was significantly greater in Group 4 than in the control group(P < 0.05),but no other groups had deeper crypts.However,villus height was significantly longer in Groups 2 and 4 than in the control group(P < 0.05).The comparison of groups revealed,significant difference between control group and Groups 2 and 4) with respect to the levels of IGF-1 and IGFBP-3(P < 0.01) 3 wk after the operation.CONCLUSION:HBOT or GH and combined therapy augmented on neomucosal formation.The use of combined therapy produced a synergistic effect on the histological,morphological and functional parameters.展开更多
Celiac disease can be triggered by upper abdominal surgery, such as vagotomy, oesophagectomy, pancreatico-duodenectomy, and gastrojejunal anastomosis. Here we report a case of a 24 year-old woman who developed celiac ...Celiac disease can be triggered by upper abdominal surgery, such as vagotomy, oesophagectomy, pancreatico-duodenectomy, and gastrojejunal anastomosis. Here we report a case of a 24 year-old woman who developed celiac disease after an ileal resection for perforated Meckel's diverticula. This is the first reported celiac case that has been triggered, not by upper abdominal surgery, but after ileal resection for Meckel's diverticula.展开更多
We thank the authors for their commentary on our paper[1]and providing the high quality clinical image.The authors described a classic case of a cirrhotic patient with fully developed Terry's nails.[2]They mention...We thank the authors for their commentary on our paper[1]and providing the high quality clinical image.The authors described a classic case of a cirrhotic patient with fully developed Terry's nails.[2]They mentioned that fully developed Terry's nails exhibit a ground-glasslike opacity of the nail bed with a distal thin brown展开更多
Home mortgage loan lending firms are exposed to many business risks.This paper focuses on the mortgage loan borrower risks and proposes a prospective loss analysis approach in regard to loan repayment defaults of borr...Home mortgage loan lending firms are exposed to many business risks.This paper focuses on the mortgage loan borrower risks and proposes a prospective loss analysis approach in regard to loan repayment defaults of borrowers.For this purpose,a predictive modeling is presented in three stages.In the first stage,occurrence of borrower defaults in a mortgage loans portfolio is modeled through the generalized linear models(GLMs)type regressions for which we specify a logistic distribution for default events.The second stage of modeling develops a survival analysis in order to estimate survival probability and hazard rate functions for individual loans.Ultimately,an expectable loss amount model is presented in the third stage as a function of conditional survival probabilities and corresponding hazard rates at loan levels.Throughout all modeling stages,a large and real data set is used as an empirical analysis case by which detailed interpretations and practical implications of the obtained results are stated.展开更多
In this paper, we give a new characterization of Mobius transformations. To do this, we extend the notion of Apollonius points of a triangle and of a pentagon, to the notion of Apollonius points of an arbitrary （2n-1...In this paper, we give a new characterization of Mobius transformations. To do this, we extend the notion of Apollonius points of a triangle and of a pentagon, to the notion of Apollonius points of an arbitrary （2n-1）-gon.展开更多
We consider the Bonnet ruled surfaces which admit only one non-trivial isometry that preserves the principal curvatures. We determine the Bonnet ruled surfaces whose generators and orthogonal trajectories form a speci...We consider the Bonnet ruled surfaces which admit only one non-trivial isometry that preserves the principal curvatures. We determine the Bonnet ruled surfaces whose generators and orthogonal trajectories form a special net called an A-net.展开更多
文摘AIM:To investigate the role of growth hormone(GH),hyperbaric oxygen therapy(HBOT) and combined therapy on the intestinal neomucosa formation of the gastric serosa.METHODS:Forty-eight male Wistar-albino rats,weighing 250-280 g,were used in this study.The rats were divided into four groups(n = 12):Group 1,control,gastric serosal patch;Group 2,gastric serosal patch + GH;Group 3,gastric serosal patch + HBOT;and Group 4,gastric serosal patch + GH + HBOT.Abdominal access was achieved through a midline incision,and after the 1-cm-long defect was created in the jejunum,a 1 cm × 1 cm patch of the gastric corpus was anastomosed to the jejunal defect.Venous blood samples were taken to determine the insulin-like growth factor 1(IGF-1) and insulin-like growth factor binding protein 3(IGFBP-3) basal levels.HBOT was performed in Groups 3 and 4.In Groups 2 and 4,human GH was given subcutaneously at a dose of 2 mg per kg/d for 28 d,beginning on the operation day.All animals were sacrificed 60 d after surgery.The jejunal segment and the gastric anastomotic area were excised for histological examination.The inflammatory process,granulation,collagen deposition and fibroblast activity at the neomucosa formation were studied and scored.Additionally,the villus density,villus height,and crypt depth were counted and recorded.The measurements of villus height and crypt depth were calculated with an ocular micrometer.New vessel growth was determined by calculatingeach new vessel in a 1 mm 2 area.RESULTS:In the histological comparison of groups,no significant differences were observed between the control group and Groups 2 and 3 with respect to epithelialization,granulation,fibroblastic activity and the inflammatory process,but significant differences were present between the control group and all others groups(Groups 2-4) with respect to angiogenesis(P < 0.01) and collagen deposition(P < 0.05,P < 0.01).Significant differences between the control group and Group 4 were also observed with respect to epithelialization and fibroblastic activity(P < 0.01 and P < 0.05,respectively).There were significant differences in villus density in all of groups compared with the control group(P < 0.05).Crypt depth was significantly greater in Group 4 than in the control group(P < 0.05),but no other groups had deeper crypts.However,villus height was significantly longer in Groups 2 and 4 than in the control group(P < 0.05).The comparison of groups revealed,significant difference between control group and Groups 2 and 4) with respect to the levels of IGF-1 and IGFBP-3(P < 0.01) 3 wk after the operation.CONCLUSION:HBOT or GH and combined therapy augmented on neomucosal formation.The use of combined therapy produced a synergistic effect on the histological,morphological and functional parameters.
文摘Celiac disease can be triggered by upper abdominal surgery, such as vagotomy, oesophagectomy, pancreatico-duodenectomy, and gastrojejunal anastomosis. Here we report a case of a 24 year-old woman who developed celiac disease after an ileal resection for perforated Meckel's diverticula. This is the first reported celiac case that has been triggered, not by upper abdominal surgery, but after ileal resection for Meckel's diverticula.
文摘We thank the authors for their commentary on our paper[1]and providing the high quality clinical image.The authors described a classic case of a cirrhotic patient with fully developed Terry's nails.[2]They mentioned that fully developed Terry's nails exhibit a ground-glasslike opacity of the nail bed with a distal thin brown
文摘Home mortgage loan lending firms are exposed to many business risks.This paper focuses on the mortgage loan borrower risks and proposes a prospective loss analysis approach in regard to loan repayment defaults of borrowers.For this purpose,a predictive modeling is presented in three stages.In the first stage,occurrence of borrower defaults in a mortgage loans portfolio is modeled through the generalized linear models(GLMs)type regressions for which we specify a logistic distribution for default events.The second stage of modeling develops a survival analysis in order to estimate survival probability and hazard rate functions for individual loans.Ultimately,an expectable loss amount model is presented in the third stage as a function of conditional survival probabilities and corresponding hazard rates at loan levels.Throughout all modeling stages,a large and real data set is used as an empirical analysis case by which detailed interpretations and practical implications of the obtained results are stated.
文摘In this paper, we give a new characterization of Mobius transformations. To do this, we extend the notion of Apollonius points of a triangle and of a pentagon, to the notion of Apollonius points of an arbitrary （2n-1）-gon.
文摘We consider the Bonnet ruled surfaces which admit only one non-trivial isometry that preserves the principal curvatures. We determine the Bonnet ruled surfaces whose generators and orthogonal trajectories form a special net called an A-net.
