Parkinson’sdisease-mildcognitiveimpairment(PD-MCI)currently represents a valid diagnostic clinical entity with potential interest for therapeutic purpose.MCI is present in approximately 25–30%of non-demented patient...Parkinson’sdisease-mildcognitiveimpairment(PD-MCI)currently represents a valid diagnostic clinical entity with potential interest for therapeutic purpose.MCI is present in approximately 25–30%of non-demented patients with PD(Weintraub et al.,2018).Several risk factors are associated with Parkinson’s disease dementia(PDD)occurrence,such asoldageatonset,longdiseaseduration,motorimpairment and MCI(Nicoletti et al.,2019).展开更多
1.The complex spectrum of neurodegenerative diseases Epidemiologic data indicate that neurodegenerative diseases(NDDs)show high prevalence with a trend of a progressively growing incidence,especially in aging societ...1.The complex spectrum of neurodegenerative diseases Epidemiologic data indicate that neurodegenerative diseases(NDDs)show high prevalence with a trend of a progressively growing incidence,especially in aging societies.This presents an increasing social and economic burden.展开更多
文摘Parkinson’sdisease-mildcognitiveimpairment(PD-MCI)currently represents a valid diagnostic clinical entity with potential interest for therapeutic purpose.MCI is present in approximately 25–30%of non-demented patients with PD(Weintraub et al.,2018).Several risk factors are associated with Parkinson’s disease dementia(PDD)occurrence,such asoldageatonset,longdiseaseduration,motorimpairment and MCI(Nicoletti et al.,2019).
文摘1.The complex spectrum of neurodegenerative diseases Epidemiologic data indicate that neurodegenerative diseases(NDDs)show high prevalence with a trend of a progressively growing incidence,especially in aging societies.This presents an increasing social and economic burden.