Obesity is a CVD risk factor that can be modulated for massive reduction in morbi-mortality. Traditional indices measuring it have been inconsistent and the most commonly used;BMI has proved inappropriate for Africans...Obesity is a CVD risk factor that can be modulated for massive reduction in morbi-mortality. Traditional indices measuring it have been inconsistent and the most commonly used;BMI has proved inappropriate for Africans, not attending specifically to body fat and its distribution. With the consensus that intra-abdominal fat is the most critical for cardio-metabolic diseases, various attempts were made to measure it for risk estimation. These however require costly equipments not easily amenable for population studies. The abdominometer conceptualized by BNO has shown promise in isolated cases. This pilot study was undertaken in this restricted population to compare its utility with existing anthropometric measures of cardiovascular disease.展开更多
Malaria was thought to be rare in neonates. However, recent studies report increasing prevalence in neonates. Clinical features of neonatal malaria have also not been adequately reported. This study was undertaken to ...Malaria was thought to be rare in neonates. However, recent studies report increasing prevalence in neonates. Clinical features of neonatal malaria have also not been adequately reported. This study was undertaken to assess the prevalence, clinical features and outcome of malaria in neonates admitted into two tertiary hospitals in Jos, Plateau State. All consecutive neonates aged 0 - 28 days admitted into the neonatal units of Jos University Teaching Hospital and Bingham University Teaching Hospital, Jos were recruited into the study. Giemsa stained blood films of the neonates were examined by trained microscopists. Neonates with malaria had presenting clinical features recorded and treated with amodiaquine (1st line) and quinine (2nd line). Clinical features and parasitaemia were monitored for 14 days for outcome. Of the 301 neonates enrolled, 16 had malaria parasitaemia giving a prevalence of 5.3%. Congenital malaria accounted for 87.5% of cases of neonatal malaria. Plasmodium falciparum mono-infection was responsible for all the cases of malaria. ITN use in pregnancy offered some protection against neonatal malaria (CI=0.2 - 0.7). The median parasite density was 255 (72, 385) parasites/μl. Fever was significantly present in 10 (66.7%) of the cases (p=0.03). Fifteen of the 16 neonates had clinical and parasitological cure on treatment with amodiaquine. One treatment failure had cure after retreatment with quinine. There was no mortality in all 16 neonates treated for malaria. Malaria is not rare in neonates on admission in Jos. Fever is the commonest clinical feature of neonatal malaria. Amodiaquine provided effective treatment of malaria in neonates in Jos.展开更多
文摘Obesity is a CVD risk factor that can be modulated for massive reduction in morbi-mortality. Traditional indices measuring it have been inconsistent and the most commonly used;BMI has proved inappropriate for Africans, not attending specifically to body fat and its distribution. With the consensus that intra-abdominal fat is the most critical for cardio-metabolic diseases, various attempts were made to measure it for risk estimation. These however require costly equipments not easily amenable for population studies. The abdominometer conceptualized by BNO has shown promise in isolated cases. This pilot study was undertaken in this restricted population to compare its utility with existing anthropometric measures of cardiovascular disease.
文摘Malaria was thought to be rare in neonates. However, recent studies report increasing prevalence in neonates. Clinical features of neonatal malaria have also not been adequately reported. This study was undertaken to assess the prevalence, clinical features and outcome of malaria in neonates admitted into two tertiary hospitals in Jos, Plateau State. All consecutive neonates aged 0 - 28 days admitted into the neonatal units of Jos University Teaching Hospital and Bingham University Teaching Hospital, Jos were recruited into the study. Giemsa stained blood films of the neonates were examined by trained microscopists. Neonates with malaria had presenting clinical features recorded and treated with amodiaquine (1st line) and quinine (2nd line). Clinical features and parasitaemia were monitored for 14 days for outcome. Of the 301 neonates enrolled, 16 had malaria parasitaemia giving a prevalence of 5.3%. Congenital malaria accounted for 87.5% of cases of neonatal malaria. Plasmodium falciparum mono-infection was responsible for all the cases of malaria. ITN use in pregnancy offered some protection against neonatal malaria (CI=0.2 - 0.7). The median parasite density was 255 (72, 385) parasites/μl. Fever was significantly present in 10 (66.7%) of the cases (p=0.03). Fifteen of the 16 neonates had clinical and parasitological cure on treatment with amodiaquine. One treatment failure had cure after retreatment with quinine. There was no mortality in all 16 neonates treated for malaria. Malaria is not rare in neonates on admission in Jos. Fever is the commonest clinical feature of neonatal malaria. Amodiaquine provided effective treatment of malaria in neonates in Jos.
