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因阵发性发作事件而入住三级癫痫治疗中心的儿童中癫痫的误诊率
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作者 uldall p. Alving J. +1 位作者 Hansen L. K. 李开(译) 《世界核心医学期刊文摘(儿科学分册)》 2006年第8期20-21,共2页
Aims:To determine the proportion of children admitted with difficult to treat paroxysmal events to a tertiary epilepsy centre who did not have epilepsy.Methods:In an observational retrospective study,all case notes of... Aims:To determine the proportion of children admitted with difficult to treat paroxysmal events to a tertiary epilepsy centre who did not have epilepsy.Methods:In an observational retrospective study,all case notes of 223 children admitted in 1997 were examined.The referral was made from the local paediatric department in 51%of cases,other departments in 27%,and from general or specialist practitioners in 22%.Doubt regarding the diagnosis of epilepsy was expressed in the referral note in 17%.On admission,86%were on antiepileptic drug treatment.During admission all children were subjected to a comprehensive intensive observation and 62%had EEG monitoring.Results:In total,39%(87/223)were found not to have epilepsy.In 30%of children(55/184)referred without any doubts about the epilepsy diagnosis,the diagnosis was disproved.Of the 159 children admitted for the first time,75(47%)were discharged with a diagnosis of non-epileptic seizures.Of 125 children admitted for the first time with no doubts about the diagnosis of epilepsy,44(35%)did not have epilepsy.Staring episodes were the most frequently encountered non-epileptic paroxysmal event.Psychogenic non-epileptic seizures were found in 12 children.A total of 34(15%)had their medication tapered off;a further 22(10%)had tapered off medication before admission.Conclusion:The present study supports the view that misdiagnosis of epilepsy is common.The treating physician should be cautious in diagnosis,especially of staring episodes.A diagnostic re-evaluation should be undertaken in difficult cases with continuing paroxysmal events in order to avoid unnecessary drug treatment and restrictions on the child’s lifestyle. 展开更多
关键词 癫痫儿童 发作事件 治疗中心 误诊率 阵发性 抗癫痫药物治疗 三级 非癫痫性发作 疑难病例 癫痫诊断
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