Introduction:There is a renewed interest for thiosemicarbazones in terms of antimicrobial,antiviral,and antitumor activity.With notable exceptions(e.g.thiopental)thiocarbonyl-containing chemical entities are commonly ...Introduction:There is a renewed interest for thiosemicarbazones in terms of antimicrobial,antiviral,and antitumor activity.With notable exceptions(e.g.thiopental)thiocarbonyl-containing chemical entities are commonly considered as non-druggable.Screening of a library of thiosemicarbazones showed,however,exceptional potential.The purpose of this work was both to develop展开更多
文摘Introduction:There is a renewed interest for thiosemicarbazones in terms of antimicrobial,antiviral,and antitumor activity.With notable exceptions(e.g.thiopental)thiocarbonyl-containing chemical entities are commonly considered as non-druggable.Screening of a library of thiosemicarbazones showed,however,exceptional potential.The purpose of this work was both to develop
