Aim:To study the effect of androgen and antiandrogen on the level of androgen receptor(AR)mRNA.Methods:The totalRNA was extracted from the prostate and analyzed by slot blot analysis,The blots were hybrid-ized with AR...Aim:To study the effect of androgen and antiandrogen on the level of androgen receptor(AR)mRNA.Methods:The totalRNA was extracted from the prostate and analyzed by slot blot analysis,The blots were hybrid-ized with ARcDNA probe and 1Aprobe(internal control)and autoradionraphy was performed.The intensity of signal was measured with a densitometer and the ratio of AR RNAand1ARNAwas calculated.Results:Androgenic deprivation produced by castration decreased the weight of the prostate and increased the levels of ARmRNA.Treatment of the castrated rats with testostrone increased the weight of prostate and decreased the levels of ARmRNA.Treatment of normal rats with flutamide decreased the weight of the gland and increased the levels of AR mRNA.Conclusion:Androgens produce proliferative effect on the prostate and negatively regulate the AR transcription.展开更多
The prime objective of the present study is to examine the effect of temperature dependent viscosity μ(T ) on the revolving axi-symmetric laminar boundary layer flow of an incompressible, electrically non-conducting ...The prime objective of the present study is to examine the effect of temperature dependent viscosity μ(T ) on the revolving axi-symmetric laminar boundary layer flow of an incompressible, electrically non-conducting ferrofluid in the presence of a stationary plate subjected to a magnetic field and maintained at a uniform temperature. To serve this purpose, the non-linear coupled partial differential equations are firstly converted into the ordinary differential equations using well-known similarity transformations. The popular finite difference method is employed to discretize the non-linear coupled differential equations. These discretized equations are then solved using the Newton method in MATLAB, for which an initial guess is made with the help of the Flex PDE Solver. Along with the velocity profiles, the effects of temperature dependent viscosity are also examined on the skin friction, the heat transfer, and the boundary layer displacement thickness. The obtained results are presented numerically as well as graphically.展开更多
Tendon autografts play an important role in upper limb reconstruction and a working knowledge of tendon autograft options is essential for the surgeon. Although palmaris longus is often the first choice, other options...Tendon autografts play an important role in upper limb reconstruction and a working knowledge of tendon autograft options is essential for the surgeon. Although palmaris longus is often the first choice, other options like plantaris, extensor Hallucis longus, flexor carpi radialis are readily available. Advantages of autografts include easy availability, satisfactory biomechanical properties and the human body tends to accept its own tendons than from a donor. This review highlights the various options available and their anatomical and surgical considerations in procuring grafts for upper limb reconstructive work.展开更多
We have measured trace elements in epileptic patients. Levels of trace elements are very fluctuating in comparison to the healthy controls. The levels of Zn, Fe and Cu are higher in comparison to healthy normal childr...We have measured trace elements in epileptic patients. Levels of trace elements are very fluctuating in comparison to the healthy controls. The levels of Zn, Fe and Cu are higher in comparison to healthy normal children about 64%, 55% and 33% respectively. The levels of Cu are just fifty percent to levels of Zn. The levels of Ca, K and Mg are higher about 10%, 9.027% and 4.2% in comparison to normal children. Sodium levels were very low in comparison to all the trace elements and are higher about 3.2% than controls. The multiple correlation coefficients between Na, K and Ca, i.e. (RNa.KCa) has a value 0.4993 in comparison to healthy children. Multiple correlation coefficients between Fe, Cu and Zn, i.e. (RFe.CuZn) has a value 0.4366. The multiple correlation coefficients RNa.Kca and?RFe.CuZn are found lower. These elements were strongly correlated with other. The multiple correlation coefficients such as RK.NaCa, RCa.K.Na, RMg.NaK, RNa.MgK, RK.MgNa, RCu.FeZn and RZn.FeCu were also evaluated and found on higher side from normal range. Trace elements may act as a catalytic agent for enzyme system of the cells. The minimum requirements of living objects for essential trace elements may be expressed in proportions or concentrations of the total dry food taken everyday. A tolerance of the human system may be fluctuated according to intake of these elements.展开更多
文摘Aim:To study the effect of androgen and antiandrogen on the level of androgen receptor(AR)mRNA.Methods:The totalRNA was extracted from the prostate and analyzed by slot blot analysis,The blots were hybrid-ized with ARcDNA probe and 1Aprobe(internal control)and autoradionraphy was performed.The intensity of signal was measured with a densitometer and the ratio of AR RNAand1ARNAwas calculated.Results:Androgenic deprivation produced by castration decreased the weight of the prostate and increased the levels of ARmRNA.Treatment of the castrated rats with testostrone increased the weight of prostate and decreased the levels of ARmRNA.Treatment of normal rats with flutamide decreased the weight of the gland and increased the levels of AR mRNA.Conclusion:Androgens produce proliferative effect on the prostate and negatively regulate the AR transcription.
文摘The prime objective of the present study is to examine the effect of temperature dependent viscosity μ(T ) on the revolving axi-symmetric laminar boundary layer flow of an incompressible, electrically non-conducting ferrofluid in the presence of a stationary plate subjected to a magnetic field and maintained at a uniform temperature. To serve this purpose, the non-linear coupled partial differential equations are firstly converted into the ordinary differential equations using well-known similarity transformations. The popular finite difference method is employed to discretize the non-linear coupled differential equations. These discretized equations are then solved using the Newton method in MATLAB, for which an initial guess is made with the help of the Flex PDE Solver. Along with the velocity profiles, the effects of temperature dependent viscosity are also examined on the skin friction, the heat transfer, and the boundary layer displacement thickness. The obtained results are presented numerically as well as graphically.
文摘Tendon autografts play an important role in upper limb reconstruction and a working knowledge of tendon autograft options is essential for the surgeon. Although palmaris longus is often the first choice, other options like plantaris, extensor Hallucis longus, flexor carpi radialis are readily available. Advantages of autografts include easy availability, satisfactory biomechanical properties and the human body tends to accept its own tendons than from a donor. This review highlights the various options available and their anatomical and surgical considerations in procuring grafts for upper limb reconstructive work.
文摘We have measured trace elements in epileptic patients. Levels of trace elements are very fluctuating in comparison to the healthy controls. The levels of Zn, Fe and Cu are higher in comparison to healthy normal children about 64%, 55% and 33% respectively. The levels of Cu are just fifty percent to levels of Zn. The levels of Ca, K and Mg are higher about 10%, 9.027% and 4.2% in comparison to normal children. Sodium levels were very low in comparison to all the trace elements and are higher about 3.2% than controls. The multiple correlation coefficients between Na, K and Ca, i.e. (RNa.KCa) has a value 0.4993 in comparison to healthy children. Multiple correlation coefficients between Fe, Cu and Zn, i.e. (RFe.CuZn) has a value 0.4366. The multiple correlation coefficients RNa.Kca and?RFe.CuZn are found lower. These elements were strongly correlated with other. The multiple correlation coefficients such as RK.NaCa, RCa.K.Na, RMg.NaK, RNa.MgK, RK.MgNa, RCu.FeZn and RZn.FeCu were also evaluated and found on higher side from normal range. Trace elements may act as a catalytic agent for enzyme system of the cells. The minimum requirements of living objects for essential trace elements may be expressed in proportions or concentrations of the total dry food taken everyday. A tolerance of the human system may be fluctuated according to intake of these elements.
