AIM:The study was initiated to evaluate the reactogenicity and immunogenicity of a recombinant hepatitis B vaccine in age group >40 years and to study the response of a single booster dose in primary non-responders...AIM:The study was initiated to evaluate the reactogenicity and immunogenicity of a recombinant hepatitis B vaccine in age group >40 years and to study the response of a single booster dose in primary non-responders to the hepatitis B vaccination. METHODS:A total of 102 volunteers without markers of hepatitis B infection (negative for HBsAg,anti-HBc antibody, HBeAg and anti-HBs antibody) received 20μg of recombinant HB vaccine intramuscularly at 0,1,and 6 months.Anti HBs titers were evaluated by a quantitative Elisa kit at 90 and 210 days.A booster dose of 20μg HB vaccine was given after 6 months of the 3^(rd) vaccine dose to the 15 non- responders and anti-HBs titers were measured after i month. RESULTS:Seroprotection (anti-HBs GMT^3 10 IU/L) was achieved in 85.3 % (87/102) volunteers.The mean GMT titers of the vaccine responders was 136.1 IU/L.Of the seroprotected individuals,there were 32.4% (33/102) hyporesponders (anti- HBs titers <10-99 mIU/ml) and 52.9% (54/102) were responders (anti-HBs titers >100 IU/L).All the non-responders (15/15) responded to a single dose of the booster dose of recombinant HB vaccine and their mean anti-HBs antibody titers were more than 100.5 mIU/ml after the booster dose. CONCLUSION:Recombinant hepatitis B vaccine offers good seroprotection in the age group >40 years and has a good safety profile.A single booster dose after 6 months in primary non-responders leads to good seroprotective anti-HBs antibody titers.However,larger population based studies are needed to evaluate the role of a booster dose in selected group of non-responders and whether such an approach will be cost effective.展开更多
The effect of hydrogen plasma treatment of iron oxide films on the growth and microstructure of carbon nanotubes(CNTs)by microwave plasma enhanced chemical vapor deposition process has been investigated.Microwave plas...The effect of hydrogen plasma treatment of iron oxide films on the growth and microstructure of carbon nanotubes(CNTs)by microwave plasma enhanced chemical vapor deposition process has been investigated.Microwave plasma was characterized in-situ using optical emission spectrometer.Morphology of the films was examined by scanning electron microscopy.Structural analysis was carried out by high resolution transmission electron microscopy(HRTEM)equipped with energy dispersive X-ray spectroscopy(EDS)and micro-diffraction attachments.It is found that oxide films without H_2 plasma pretreatment or treated for lesser time resulted in CNT films with high percentage of carbonaceous particles and with embedded particles/nanorods distributed discontinuously in the cavity of the nanotubes.The embedded particles were found to be of iron carbide(Fe-C)as confirmed by HRTEM,EDS and micro-diffraction analysis.Experimental observations suggested that the iron oxide particles had poor catalytic action for CNT growth and in-situ reduction of oxide clusters to Fe by hydrogen plasma plays a key role in discontinuous filling of the nanotubes by the catalytic particles.展开更多
In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate ...In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate genotypexenvironmental interactions for adaptability and stability at the age of 30 months in three geographical locations in the state of Punjab, India. Clone 124 had maximum adaptability and stability （bi = 1.04） to perform exceedingly well over the locations. Clones 36 and 1 were stable with mean regression coefficient of 0.84 and 1.22, respectively. Nonetheless, clone 4 1 performed exceedingly well for all the characters to attain maximum population mean, and the perform- ance varied substantially across the locations. Therefore, clone 41 was considered as productive but non-adaptive clone. Though some of the clones were sensitive to sites, 14 clones for height, 16 for collar diameter, 12 for DBH and 7 for volume were relatively un-sensitive with higher regression coefficient. Nonetheless, clone 124 was the most Stable with average bi value of 1.04 and productive, which could play an important role in future breeding and commercial deployment of stable and produc- tive planting stock of Dalbergia sissoo.展开更多
Through Wireless Sensor Networks(WSN)formation,industrial and academic communities have seen remarkable development in recent decades.One of the most common techniques to derive the best out of wireless sensor network...Through Wireless Sensor Networks(WSN)formation,industrial and academic communities have seen remarkable development in recent decades.One of the most common techniques to derive the best out of wireless sensor networks is to upgrade the operating group.The most important problem is the arrangement of optimal number of sensor nodes as clusters to discuss clustering method.In this method,new client nodes and dynamic methods are used to determine the optimal number of clusters and cluster heads which are to be better organized and proposed to classify each round.Parameters of effective energy use and the ability to decide the best method of attachments are included.The Problem coverage find change ability network route due to which traffic and delays keep the performance to be very high.A newer version of Gravity Analysis Algorithm(GAA)is used to solve this problem.This proposed new approach GAA is introduced to improve network lifetime,increase system energy efficiency and end delay performance.Simulation results show that modified GAA performance is better than other networks and it has more advanced Life Time Delay Clustering Algorithms-LTDCA protocols.The proposed method provides a set of data collection and increased throughput in wireless sensor networks.展开更多
Background The response of superheated emulsion detector with different halocarbons as active liquid to poly-energetic and mono-energetic neutrons has been carried out by different workers.The C_(2)H_(2)F_(4)detectors...Background The response of superheated emulsion detector with different halocarbons as active liquid to poly-energetic and mono-energetic neutrons has been carried out by different workers.The C_(2)H_(2)F_(4)detectors have not been explored much.This liquid has shown the potentiality of sensitivity to low-mass dark matter.The previous calibration of this liquid was carried out with the poly-energetic neutrons.Purpose In the present work,to better characterize the detector with neutrons,it is irradiated with quasi-mono-energetic neutrons and the results are compared with neutrons from 241Am-Be.To run the detector for the dark matter search,it is required to calibrate it with neutrons,preferably with mono-energetic neutrons.But mono-energetic neutron is not available at all establishments;hence,it was calibrated with quasi-mono-energetic neutrons.Method The response of superheated emulsion consisting of the droplets of C_(2)H_(2)F_(4)has been studied using the quasi-mono-energetic neutrons.The superheated droplets have been fabricated in a visco-elastic gel matrix.The shock waves generated by the passage of the energetic particles are detected by the acoustic sensors coupled to the emulsion.The measurement has also been carried out for the blank target and beam-off conditions.Results and conclusion It is observed that the(Pvar)response of the emulsion in the low-frequency range is sharper for the quasi-mono-energetic neutrons from 7Li(p,n)reaction and wider for the poly-energetic neutrons from 241Am-Be.The fundamental frequency associated with bubble nucleation(FF values)is similar for the neutrons from 7Li-target and 241Am-Be source.The precise characterization of such detector is required for the application in neutron measurement as well as for the dark matter search experiment apart from the basic understanding of the radiation-induced bubble nucleation.展开更多
This study was conducted in the Banni region of the Gujarat State,India,which is located in the western-most end of the country.The main objective was to investigate the local perceptions of grassland change,regenerat...This study was conducted in the Banni region of the Gujarat State,India,which is located in the western-most end of the country.The main objective was to investigate the local perceptions of grassland change,regeneration potentiality,socio-economic status and fac-tors that cause degradation of the vegetation resources in Banni.Participatory Rural Appraisal(PRA)was employed to generate the socio-economic profile of interviewed villages or hamlets.Information on vegetation deteriora-tion and changes in species composition significant for sustainable management of grassland was obtained through interviews with 51 elderly maldharies(pastoral-ists)and local inhabitants living in 31 villages in Banni.Local people had observed a change in the local surrounding habitats from grassland to woodland(domi-nated by Prosopis juliflora,locally called Gando Bavar)during their lifetime and considered it primarily a result of frequent intensive drought,constructed dams on flooding rivers in Banni,and declining rainfall.The socio-economic survey showed that the Banni communities are highly dependent on the natural grassland for various purposes.In particular,nine woody species were useful for construction of the traditional house called Bhunga,four for medicine and 22 for livestock fodder.Highly preferred and declining species were characteristically large wild thorny trees with edible fruits,viz.Acacia nilotica subsp.indica(Bavar),Prosopis cineraria(Kandho),and Salvadora persica(Kharijar).Some of the locally highly preferred grass species were also considered to be declining in the local environs;they included Dichanthium annulatum(Jinjvo),Cenchrus ciliaris(Dhaman),Sporobolus fertilis(Khevai)and Chloris barbata(Siyarpuchha).The study furthermore identified a close coincidence between the interest in conserving tree species diversity nearby the natural water resources and priorities of local inhabitants,which included protection of plenty of large trees(including many fruit tress,viz.Mangifera indicia(Ambo),Cordia dichotoma(Gunda)and Pithecellobium dulce(Gora-samli)),improvement of woody fodder tree and grass species regeneration,and reduction of overgrazing pres-sure on grasslands.Focusing management strategies on increasing the populations of such declining and highly preferred tree and grass species,by active restoration and grazing policies,would enhance the natural resource value and biodiversity wealth considerably and thereby the quality of life for the local inhabitants.The implications of the results are discussed and recommendations are suggested for conservation,management,and sustainable utilization of the fragile grassland ecosystem of the Banni region.展开更多
文摘AIM:The study was initiated to evaluate the reactogenicity and immunogenicity of a recombinant hepatitis B vaccine in age group >40 years and to study the response of a single booster dose in primary non-responders to the hepatitis B vaccination. METHODS:A total of 102 volunteers without markers of hepatitis B infection (negative for HBsAg,anti-HBc antibody, HBeAg and anti-HBs antibody) received 20μg of recombinant HB vaccine intramuscularly at 0,1,and 6 months.Anti HBs titers were evaluated by a quantitative Elisa kit at 90 and 210 days.A booster dose of 20μg HB vaccine was given after 6 months of the 3^(rd) vaccine dose to the 15 non- responders and anti-HBs titers were measured after i month. RESULTS:Seroprotection (anti-HBs GMT^3 10 IU/L) was achieved in 85.3 % (87/102) volunteers.The mean GMT titers of the vaccine responders was 136.1 IU/L.Of the seroprotected individuals,there were 32.4% (33/102) hyporesponders (anti- HBs titers <10-99 mIU/ml) and 52.9% (54/102) were responders (anti-HBs titers >100 IU/L).All the non-responders (15/15) responded to a single dose of the booster dose of recombinant HB vaccine and their mean anti-HBs antibody titers were more than 100.5 mIU/ml after the booster dose. CONCLUSION:Recombinant hepatitis B vaccine offers good seroprotection in the age group >40 years and has a good safety profile.A single booster dose after 6 months in primary non-responders leads to good seroprotective anti-HBs antibody titers.However,larger population based studies are needed to evaluate the role of a booster dose in selected group of non-responders and whether such an approach will be cost effective.
文摘The effect of hydrogen plasma treatment of iron oxide films on the growth and microstructure of carbon nanotubes(CNTs)by microwave plasma enhanced chemical vapor deposition process has been investigated.Microwave plasma was characterized in-situ using optical emission spectrometer.Morphology of the films was examined by scanning electron microscopy.Structural analysis was carried out by high resolution transmission electron microscopy(HRTEM)equipped with energy dispersive X-ray spectroscopy(EDS)and micro-diffraction attachments.It is found that oxide films without H_2 plasma pretreatment or treated for lesser time resulted in CNT films with high percentage of carbonaceous particles and with embedded particles/nanorods distributed discontinuously in the cavity of the nanotubes.The embedded particles were found to be of iron carbide(Fe-C)as confirmed by HRTEM,EDS and micro-diffraction analysis.Experimental observations suggested that the iron oxide particles had poor catalytic action for CNT growth and in-situ reduction of oxide clusters to Fe by hydrogen plasma plays a key role in discontinuous filling of the nanotubes by the catalytic particles.
文摘In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate genotypexenvironmental interactions for adaptability and stability at the age of 30 months in three geographical locations in the state of Punjab, India. Clone 124 had maximum adaptability and stability （bi = 1.04） to perform exceedingly well over the locations. Clones 36 and 1 were stable with mean regression coefficient of 0.84 and 1.22, respectively. Nonetheless, clone 4 1 performed exceedingly well for all the characters to attain maximum population mean, and the perform- ance varied substantially across the locations. Therefore, clone 41 was considered as productive but non-adaptive clone. Though some of the clones were sensitive to sites, 14 clones for height, 16 for collar diameter, 12 for DBH and 7 for volume were relatively un-sensitive with higher regression coefficient. Nonetheless, clone 124 was the most Stable with average bi value of 1.04 and productive, which could play an important role in future breeding and commercial deployment of stable and produc- tive planting stock of Dalbergia sissoo.
文摘Through Wireless Sensor Networks(WSN)formation,industrial and academic communities have seen remarkable development in recent decades.One of the most common techniques to derive the best out of wireless sensor networks is to upgrade the operating group.The most important problem is the arrangement of optimal number of sensor nodes as clusters to discuss clustering method.In this method,new client nodes and dynamic methods are used to determine the optimal number of clusters and cluster heads which are to be better organized and proposed to classify each round.Parameters of effective energy use and the ability to decide the best method of attachments are included.The Problem coverage find change ability network route due to which traffic and delays keep the performance to be very high.A newer version of Gravity Analysis Algorithm(GAA)is used to solve this problem.This proposed new approach GAA is introduced to improve network lifetime,increase system energy efficiency and end delay performance.Simulation results show that modified GAA performance is better than other networks and it has more advanced Life Time Delay Clustering Algorithms-LTDCA protocols.The proposed method provides a set of data collection and increased throughput in wireless sensor networks.
文摘Background The response of superheated emulsion detector with different halocarbons as active liquid to poly-energetic and mono-energetic neutrons has been carried out by different workers.The C_(2)H_(2)F_(4)detectors have not been explored much.This liquid has shown the potentiality of sensitivity to low-mass dark matter.The previous calibration of this liquid was carried out with the poly-energetic neutrons.Purpose In the present work,to better characterize the detector with neutrons,it is irradiated with quasi-mono-energetic neutrons and the results are compared with neutrons from 241Am-Be.To run the detector for the dark matter search,it is required to calibrate it with neutrons,preferably with mono-energetic neutrons.But mono-energetic neutron is not available at all establishments;hence,it was calibrated with quasi-mono-energetic neutrons.Method The response of superheated emulsion consisting of the droplets of C_(2)H_(2)F_(4)has been studied using the quasi-mono-energetic neutrons.The superheated droplets have been fabricated in a visco-elastic gel matrix.The shock waves generated by the passage of the energetic particles are detected by the acoustic sensors coupled to the emulsion.The measurement has also been carried out for the blank target and beam-off conditions.Results and conclusion It is observed that the(Pvar)response of the emulsion in the low-frequency range is sharper for the quasi-mono-energetic neutrons from 7Li(p,n)reaction and wider for the poly-energetic neutrons from 241Am-Be.The fundamental frequency associated with bubble nucleation(FF values)is similar for the neutrons from 7Li-target and 241Am-Be source.The precise characterization of such detector is required for the application in neutron measurement as well as for the dark matter search experiment apart from the basic understanding of the radiation-induced bubble nucleation.
文摘This study was conducted in the Banni region of the Gujarat State,India,which is located in the western-most end of the country.The main objective was to investigate the local perceptions of grassland change,regeneration potentiality,socio-economic status and fac-tors that cause degradation of the vegetation resources in Banni.Participatory Rural Appraisal(PRA)was employed to generate the socio-economic profile of interviewed villages or hamlets.Information on vegetation deteriora-tion and changes in species composition significant for sustainable management of grassland was obtained through interviews with 51 elderly maldharies(pastoral-ists)and local inhabitants living in 31 villages in Banni.Local people had observed a change in the local surrounding habitats from grassland to woodland(domi-nated by Prosopis juliflora,locally called Gando Bavar)during their lifetime and considered it primarily a result of frequent intensive drought,constructed dams on flooding rivers in Banni,and declining rainfall.The socio-economic survey showed that the Banni communities are highly dependent on the natural grassland for various purposes.In particular,nine woody species were useful for construction of the traditional house called Bhunga,four for medicine and 22 for livestock fodder.Highly preferred and declining species were characteristically large wild thorny trees with edible fruits,viz.Acacia nilotica subsp.indica(Bavar),Prosopis cineraria(Kandho),and Salvadora persica(Kharijar).Some of the locally highly preferred grass species were also considered to be declining in the local environs;they included Dichanthium annulatum(Jinjvo),Cenchrus ciliaris(Dhaman),Sporobolus fertilis(Khevai)and Chloris barbata(Siyarpuchha).The study furthermore identified a close coincidence between the interest in conserving tree species diversity nearby the natural water resources and priorities of local inhabitants,which included protection of plenty of large trees(including many fruit tress,viz.Mangifera indicia(Ambo),Cordia dichotoma(Gunda)and Pithecellobium dulce(Gora-samli)),improvement of woody fodder tree and grass species regeneration,and reduction of overgrazing pres-sure on grasslands.Focusing management strategies on increasing the populations of such declining and highly preferred tree and grass species,by active restoration and grazing policies,would enhance the natural resource value and biodiversity wealth considerably and thereby the quality of life for the local inhabitants.The implications of the results are discussed and recommendations are suggested for conservation,management,and sustainable utilization of the fragile grassland ecosystem of the Banni region.
