OPTICAL MEA SUREMENTS OF RAT MUSCLE SAMPLES UND ER TREATMENT WITH ETHYLENE GLYCOL AND GLUCOSE

With the objective to study the variation of optical properties of rat muscle during optical clearing,we have performed a set of optical measurements from that kind of tissue.The.measurements performed were total tr ansmittance,ollimated transmit tance,specular reflec-tance and total reflectance.This set of measurements is suficient to determine diffuse reflectance and absorbance of the sample,also necessary to est imate the optical properties.All the per formed measurements and calculated quantities will be used later in inverse Monte Carlo(IMC)simu-lations to determine the evolution of the optical properties of muscle during treatments with ethylene glycol and glucose.The results obt ained with the measurements already provide some information about the optical c learing treatments applied to the muscle and translate the mechanisms of turning the tissue more transparent and sequence of regimes of optical clearing.

用激光散斑技术监测药物作用下淋巴流的变化

本文采用激光散斑零点法 (ZCL S)监测了在不同剂量的盐酸异丙肾上腺素作用下大鼠肠系膜上淋巴流的流速变化 ,并与传统的单帧分析方法获得的结果进行比较。两种方法获得的平均流速变化一致 :开始时随着盐酸异丙肾上腺素浓度的增加 (10 - 7mol/ L～ 10 - 5mol/ L) ,淋巴流平均流速减小 ;在浓度为10 - 5mol/ L 时 ,淋巴流平均流速减小达到显著性水平 ;当浓度继续增加至 10 - 4m ol/ L,平均流速开始增加 ,但未达到显著性水平。不同的是 ,采用本文方法同时获得了淋巴流流速的实时动态特征 ,在药物作用下 ,其动态特征也发生了改变。