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原发性生殖器疱疹中单纯疱疹病毒1型的重要意义
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作者 Nieuwenhuis R.F. van doornum g.j.j. +1 位作者 Mulder P.G.H. 冯义国 《世界核心医学期刊文摘(皮肤病学分册)》 2006年第10期20-21,共2页
Herpes simplex virus type 1(HSV-1)is increasingly reported in primary genital herpes.Its incidence was assessed among Rotterdam sexually transmitted diseases clinic attendees between 1996 and 2001,and demographic and ... Herpes simplex virus type 1(HSV-1)is increasingly reported in primary genital herpes.Its incidence was assessed among Rotterdam sexually transmitted diseases clinic attendees between 1996 and 2001,and demographic and sexual behaviour factors were evaluated.A retrospective record analysiswas performed.All herpes diagnoses were based on cell culture techniques.A clinical scoring system was used to select “primary”cases.Demographic and sexual behaviour characteristics were analysed using logistic regression.The clinical scoring system showed 115 cases of primary genital herpes.HSV-1(n=60)was found in 52%and HSV-2(n=55)in 48%of cases.The multiple logistic regression model showed that HSV-1 was associated with “oro-genital contact”(p < 0.001)and “having a single partner in the last 2 months”(p=0.054)and that HSV-2 was associated with “a higher number of sexual partners in the last 6 months”(p=0.085).Our data confirm the growing importance of HSV-1 in primary genital herpes;oro-genital sex is the main risk factor. 展开更多
关键词 单纯疱疹病毒 性传播疾病 临床评分 细胞培养技术 性伴侣 人口统计 回归模型 记录分析
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新西兰有同性性行为HIV阳性男性肛周人乳头瘤病毒感染的患病率和清除率
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作者 van Der Snoek E.M. Niesters H.G.M. +1 位作者 van doornum g.j.j. 李政霄 《世界核心医学期刊文摘(皮肤病学分册)》 2005年第12期22-23,共2页
This study was performed to establish the prevalence of perianal human papillomavirus (HPV) infection in relation to HIV- positivity in a group of men who have sex with men (MSM), and to correlate follow- up data with... This study was performed to establish the prevalence of perianal human papillomavirus (HPV) infection in relation to HIV- positivity in a group of men who have sex with men (MSM), and to correlate follow- up data with regard to acquisition and clearance of HPV infection. Data with regard to HPV prevalence and HIV serostatus during two visits were compared. At both visits participants underwent a routine venereological examination and swabs were taken from the perianal region for HPV DNA testing. During both visits HPV types 16, 18, 31, 33 and 52 were, significantly more often detected in HIV positive individuals. Persistence of HPV type 31 at the perianal region was significantly more often seen in HIV- positive MSM, (p=0.036)while the incidence of type 16 may be associatedwith HIV positivity (p=0.059). In HIV- positive MSM significantly more high- risk HPV types were detected at the perianal region. 展开更多
关键词 HIV阳性 同性性行为 肛周 清除率 人乳头瘤病毒 检查和 拭子
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