AIMTo determine the risk factors for acute endophthalmitis after cataract extraction in a tertiary care centre in India.METHODSWe performed a nested case control study within a retrospective cohort. The surgical recor...AIMTo determine the risk factors for acute endophthalmitis after cataract extraction in a tertiary care centre in India.METHODSWe performed a nested case control study within a retrospective cohort. The surgical records of all patients with clinically diagnosed endophthalmitis within one month after cataract surgery, performed between January 2006 and December 2009, were reviewed. These were compared with randomly selected age and gender-matched controls, from patients having routine cataract surgery within ±1wk of the endophthalmitis case. Univariable and multivariable analysis were performed to identify risk factors for endophthalmitis.RESULTSOf the total 33 856 cataract surgeries performed during this period, there were 57 cases of postoperative acute endophthalmitis that met our study criteria. Thus, the overall incidence of endophthalmitis in our cohort was 1.6 per 1000 cataract extractions performed. Mean age of cases was 55.9y (SD: 10.9y) and for controls was 55.6y (SD: 9.8y). Thirty-five cases (61.4%) and 133 controls (59.6%) were males. Median time of onset of endophthalmitis was 4d (IQR 2-9d; range: 1-30d). Thirty-nine cases (68.4%) presented within 7d and 27 cases (47.4%) were culture positive. Two hundred and twenty-three age and gender matched controls were selected. In multivariate analysis, endophthalmitis was associated with posterior capsular rupture (PCR) during surgery (OR 6.98, 95%CI: 2.22-21.98), phacoemulsification via scleral incision with a foldable intraocular lens (IOL) implantation (OR 3.02, 95%CI: 1.13-8.04) and ocular co-morbidity (OR 2.32, 95%CI: 1.11-4.87).CONCLUSIONPCR, presence of ocular co-morbidity, and phacoemulsification via scleral incision with foldable-IOL were found to be independent risk factors for acute endophthalmitis.展开更多
Dear Editor,I ridocorneal endothelial syndrome(ICE)is a rare,usually unilateral,acquired condition,hypothesized to be secondary to a viral etiology[1].It affects females more often than males and comprises of three di...Dear Editor,I ridocorneal endothelial syndrome(ICE)is a rare,usually unilateral,acquired condition,hypothesized to be secondary to a viral etiology[1].It affects females more often than males and comprises of three distinct clinical types related to endothelial proliferation and its structural abnormalities.Proliferation of endothelium over the iridocorneal angle leads to progressive secondary angle closure and that over the iris leads to typical changes of polycoria and atrophy.Three clinical entities included in the syndrome are Chandlers(predominant corneal involvement),progressive iris atrophy(predominant iris involvement with polycoria and‘holes’)and Cogan Reese(iris nodules with loss of stromal features).No matter what the clinical type,it is a progressive condition and controlling intraocular pressure(IOP)and maintaining corneal clarity in the long term is usually a challenge.展开更多
文摘AIMTo determine the risk factors for acute endophthalmitis after cataract extraction in a tertiary care centre in India.METHODSWe performed a nested case control study within a retrospective cohort. The surgical records of all patients with clinically diagnosed endophthalmitis within one month after cataract surgery, performed between January 2006 and December 2009, were reviewed. These were compared with randomly selected age and gender-matched controls, from patients having routine cataract surgery within ±1wk of the endophthalmitis case. Univariable and multivariable analysis were performed to identify risk factors for endophthalmitis.RESULTSOf the total 33 856 cataract surgeries performed during this period, there were 57 cases of postoperative acute endophthalmitis that met our study criteria. Thus, the overall incidence of endophthalmitis in our cohort was 1.6 per 1000 cataract extractions performed. Mean age of cases was 55.9y (SD: 10.9y) and for controls was 55.6y (SD: 9.8y). Thirty-five cases (61.4%) and 133 controls (59.6%) were males. Median time of onset of endophthalmitis was 4d (IQR 2-9d; range: 1-30d). Thirty-nine cases (68.4%) presented within 7d and 27 cases (47.4%) were culture positive. Two hundred and twenty-three age and gender matched controls were selected. In multivariate analysis, endophthalmitis was associated with posterior capsular rupture (PCR) during surgery (OR 6.98, 95%CI: 2.22-21.98), phacoemulsification via scleral incision with a foldable intraocular lens (IOL) implantation (OR 3.02, 95%CI: 1.13-8.04) and ocular co-morbidity (OR 2.32, 95%CI: 1.11-4.87).CONCLUSIONPCR, presence of ocular co-morbidity, and phacoemulsification via scleral incision with foldable-IOL were found to be independent risk factors for acute endophthalmitis.
文摘Dear Editor,I ridocorneal endothelial syndrome(ICE)is a rare,usually unilateral,acquired condition,hypothesized to be secondary to a viral etiology[1].It affects females more often than males and comprises of three distinct clinical types related to endothelial proliferation and its structural abnormalities.Proliferation of endothelium over the iridocorneal angle leads to progressive secondary angle closure and that over the iris leads to typical changes of polycoria and atrophy.Three clinical entities included in the syndrome are Chandlers(predominant corneal involvement),progressive iris atrophy(predominant iris involvement with polycoria and‘holes’)and Cogan Reese(iris nodules with loss of stromal features).No matter what the clinical type,it is a progressive condition and controlling intraocular pressure(IOP)and maintaining corneal clarity in the long term is usually a challenge.
