Background: To compare two methods of measuring intraocular pressure (IOP) and to evaluate whether repeated measurements taken with the Ocuton S applanation s elf-tonometer can improve reliability. Methods: Ocuton S a...Background: To compare two methods of measuring intraocular pressure (IOP) and to evaluate whether repeated measurements taken with the Ocuton S applanation s elf-tonometer can improve reliability. Methods: Ocuton S and Goldmann applanati on tonometry (GAT), and corneal thickness measurements taken with the Orbscan to pography system, were successfully performed in 64 of 68 glaucoma patients. Resu lts: The median IOPs were 15.5mmHg using GAT, and 16 mmHg using the first self- taken Ocuton S measurement (n=64). The differences between the median of the GAT measurements and the first Ocuton S measurement, and the medians of the three a nd six separate Ocuton S measurements were within 3 mmHg in 52%, 59%and 67%of cases, respectively. The mean corneal thickness of all evaluated eyes was 545.3 μm. There was no effect of corneal thickness on the accuracy of either of the two devices (P > 0.05). Conclusion: Repeated measurements can improve the reliab ility of the Ocuton S. However, ever with repeated measurements only every secon d patient succeeds in obtaining reliable measurements.展开更多
Background/aim: Current evidence suggests that vascular insufficiencies in the optic nerve head play an important part in the pathogenesis of glaucomatous optic neuropathy. Trabeculectomy is the most common operative ...Background/aim: Current evidence suggests that vascular insufficiencies in the optic nerve head play an important part in the pathogenesis of glaucomatous optic neuropathy. Trabeculectomy is the most common operative procedure for the treatment of medically uncontrolled glaucoma. This study was conducted to investigate whether trabeculectomy may improve ocular haemodynamics. Methods:30 patients with primary open angle glaucoma about to undergo trabeculectomy were included in the study. Patients were evaluated before surgery and at 2 and 10 weeks after trabeculectomy. Optic nerve head blood flow (OnhBF) was assessed with scanning laser Doppler flowmetry. Fundus pulsation amplitude (FPA) measurements were obtained with laser interferometry. Results: Because of the decrease in intraocular pressure there was a significant increase in ocular perfusion pressure (OPP) following trabeculectomy (18.5% (SD 12.0% ) and 19.0% (17.1% ) at 2 and 10 weeks postoperatively; P < 0.001). A significant increase in OnhBF was observed after trabeculectomy (11.6% (16.4% ) and 16.2% (20.2% ) for each postoperative visit, respectively; P< 0.001)-. FPA was also significantly higher compared with baseline values (17.2% (17.3% ) and 17.4% (16.3% ), respectively; P< 0.001). A significant association between the increase in OPP and the increase in OnhBF and FPA was observed 10 weeks after surgery (r=0.47; P=0.009, and r=0.50; P=0.005, respectively). Conclusion: The results of this study suggest that trabeculectomy improves ocular blood flow in patientswith chronic open angle glaucoma.展开更多
文摘Background: To compare two methods of measuring intraocular pressure (IOP) and to evaluate whether repeated measurements taken with the Ocuton S applanation s elf-tonometer can improve reliability. Methods: Ocuton S and Goldmann applanati on tonometry (GAT), and corneal thickness measurements taken with the Orbscan to pography system, were successfully performed in 64 of 68 glaucoma patients. Resu lts: The median IOPs were 15.5mmHg using GAT, and 16 mmHg using the first self- taken Ocuton S measurement (n=64). The differences between the median of the GAT measurements and the first Ocuton S measurement, and the medians of the three a nd six separate Ocuton S measurements were within 3 mmHg in 52%, 59%and 67%of cases, respectively. The mean corneal thickness of all evaluated eyes was 545.3 μm. There was no effect of corneal thickness on the accuracy of either of the two devices (P > 0.05). Conclusion: Repeated measurements can improve the reliab ility of the Ocuton S. However, ever with repeated measurements only every secon d patient succeeds in obtaining reliable measurements.
文摘Background/aim: Current evidence suggests that vascular insufficiencies in the optic nerve head play an important part in the pathogenesis of glaucomatous optic neuropathy. Trabeculectomy is the most common operative procedure for the treatment of medically uncontrolled glaucoma. This study was conducted to investigate whether trabeculectomy may improve ocular haemodynamics. Methods:30 patients with primary open angle glaucoma about to undergo trabeculectomy were included in the study. Patients were evaluated before surgery and at 2 and 10 weeks after trabeculectomy. Optic nerve head blood flow (OnhBF) was assessed with scanning laser Doppler flowmetry. Fundus pulsation amplitude (FPA) measurements were obtained with laser interferometry. Results: Because of the decrease in intraocular pressure there was a significant increase in ocular perfusion pressure (OPP) following trabeculectomy (18.5% (SD 12.0% ) and 19.0% (17.1% ) at 2 and 10 weeks postoperatively; P < 0.001). A significant increase in OnhBF was observed after trabeculectomy (11.6% (16.4% ) and 16.2% (20.2% ) for each postoperative visit, respectively; P< 0.001)-. FPA was also significantly higher compared with baseline values (17.2% (17.3% ) and 17.4% (16.3% ), respectively; P< 0.001). A significant association between the increase in OPP and the increase in OnhBF and FPA was observed 10 weeks after surgery (r=0.47; P=0.009, and r=0.50; P=0.005, respectively). Conclusion: The results of this study suggest that trabeculectomy improves ocular blood flow in patientswith chronic open angle glaucoma.
