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Lecithin organogel: A unique micellar system for the delivery of bioactive agents in the treatment of skin aging 被引量:1
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作者 Sushil Raut Santosh Singh Bhadoriya +3 位作者 Vaibhav Uplanchiwar vijay mishra Avinash Gahane Sunil Kumar Jain 《Acta Pharmaceutica Sinica B》 SCIE CAS 2012年第1期8-15,共8页
Skin aging is an unavoidable aspect of human life.Premature skin aging can result from poor care,environmental pollutants,and ultraviolet radiation exposure.Wrinkles,lines,spots,uneven skin tone,and pigmentation are o... Skin aging is an unavoidable aspect of human life.Premature skin aging can result from poor care,environmental pollutants,and ultraviolet radiation exposure.Wrinkles,lines,spots,uneven skin tone,and pigmentation are often indicators of skin aging.One cannot avoid aging but cosmetics and pharmaceutical approaches can minimize and delay the damage.Topical applications of biocompatible and biodegradable vehicles have been explored for delivering anti-aging compounds.Lecithin organogel(LO)is an effective vehicle for topical delivery of many bioactive agents used in aging treatment.Lecithin is cell component isolated from soya beans or eggs and purified to show excellent gelation in non-polar solvents when combined with water.LO can form a heat-stable,resistant to microbial growth,visco-elastic,optically transparent,and non-birefringent micellar system.It serves as an organic medium to enhance dermal permeation of poorly permeable drugs by effectively partitioning into the skin.Its ability to dissolve in hydrophilic as well as in lipophilic drugs makes it a dynamic vehicle,which can be explored as a carrier for anti-aging agents. 展开更多
关键词 Skin aging TOPICAL LECITHIN BIOCOMPATIBLE ORGANOGEL
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Delonix regia: historic perspectives and modern phytochemical and pharmacological researches
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作者 Anuj Modi vijay mishra +4 位作者 Ajita Bhatt Aviral Jain Mohd. Hashim Mansoori Ekta Gurnany Vimal Kumar 《Chinese Journal of Natural Medicines》 SCIE CAS CSCD 2016年第1期31-39,共9页
Delonix regia(Bojer ex Hook)Raffin(Fabaceae),also known as flame of forest,is a semi-deciduous tree,distributed throughout Madagascar,India,Africa,and Northern Australia.Various parts of the plant are traditionally us... Delonix regia(Bojer ex Hook)Raffin(Fabaceae),also known as flame of forest,is a semi-deciduous tree,distributed throughout Madagascar,India,Africa,and Northern Australia.Various parts of the plant are traditionally used for the treatment of different ailments such as inflammation,rheumatism,bronchitis,diabetes,anemia,fever,gynecological disorders,and pneumonia.The plant possess antioxidant,hepatoprotective,gastroprotective,wound healing,antiarthritic,larvicidal,antimalarial,antiemetic,antibacterial,antifungal,antiinflammatory,analgesic,antidiarrhoeal,antiheamolytic,diuretic,and anthelmintic activities.This review is an up-to-date compilation on its traditional uses in context to phytochemical and pharmacological perspectives. 展开更多
关键词 Detonix regia FABACEAE PHYTOCHEMISTRY PHARMACOLOGY
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