Background.Mature cystic teratoma of the ovary(MCTO)is the most common ovarian germ cell n eoplasm and is usually diagnosed in early adulthood.Malignant transfor-mation is rare,occurring in approximately 2%of all case...Background.Mature cystic teratoma of the ovary(MCTO)is the most common ovarian germ cell n eoplasm and is usually diagnosed in early adulthood.Malignant transfor-mation is rare,occurring in approximately 2%of all cases.Though malignant transformation ca n occur from any of the embryonic germ layers,the most comm on malignancy arising in these otherwise benign tu mors is squamous cell carcinoma.Case.We present a patien t with aMCTO where malignant transformation of gastro intestinal epithelium re-sulted in moderately differentiate d adenocarcinoma.After 3years of follow-up,she remains free of disease.Conclu-sion.Although gastrointestinal ep ithelium is often found in MCTOs,adenocarcinoma arising from this cell type is un-common.This is the third reported ca se of adenocarcinoma arising in gastrointestinal epithelium of a MCTO.展开更多
Objectives. Pediatric embryonal heterologous rhabdomyosarcoma of the cervix is a rare tumor. Methods. We present an interesting clinico-pathologic situation of two sisters presenting with pediatric embryonal heterolog...Objectives. Pediatric embryonal heterologous rhabdomyosarcoma of the cervix is a rare tumor. Methods. We present an interesting clinico-pathologic situation of two sisters presenting with pediatric embryonal heterologous rhabdomyosarcoma of the cervix. Results. Pediatric embryonal heterologous rhabdomyosarcomas of the cervix are relatively uncommon. After a Pubmed search from 1952 to present, to our knowledge, this is the only report involving sisters presenting with this disease. Treatment has been extrapolated from collaborative groups such as Intergroup Rhabdomyosarcoma Study (IRS) Group so that optimal management may be achieved. Conclusions. We urge continued reporting of these rare tumors to enhance understanding if there may be a genetic component associated with them.展开更多
文摘Background.Mature cystic teratoma of the ovary(MCTO)is the most common ovarian germ cell n eoplasm and is usually diagnosed in early adulthood.Malignant transfor-mation is rare,occurring in approximately 2%of all cases.Though malignant transformation ca n occur from any of the embryonic germ layers,the most comm on malignancy arising in these otherwise benign tu mors is squamous cell carcinoma.Case.We present a patien t with aMCTO where malignant transformation of gastro intestinal epithelium re-sulted in moderately differentiate d adenocarcinoma.After 3years of follow-up,she remains free of disease.Conclu-sion.Although gastrointestinal ep ithelium is often found in MCTOs,adenocarcinoma arising from this cell type is un-common.This is the third reported ca se of adenocarcinoma arising in gastrointestinal epithelium of a MCTO.
文摘Objectives. Pediatric embryonal heterologous rhabdomyosarcoma of the cervix is a rare tumor. Methods. We present an interesting clinico-pathologic situation of two sisters presenting with pediatric embryonal heterologous rhabdomyosarcoma of the cervix. Results. Pediatric embryonal heterologous rhabdomyosarcomas of the cervix are relatively uncommon. After a Pubmed search from 1952 to present, to our knowledge, this is the only report involving sisters presenting with this disease. Treatment has been extrapolated from collaborative groups such as Intergroup Rhabdomyosarcoma Study (IRS) Group so that optimal management may be achieved. Conclusions. We urge continued reporting of these rare tumors to enhance understanding if there may be a genetic component associated with them.
