An efficient coronavirus disease 2019(COVID-19)vaccine is urgently required to fight the pandemic due to its high transmission rate and quick dissemination.There have been numerous reports on the side effects of the C...An efficient coronavirus disease 2019(COVID-19)vaccine is urgently required to fight the pandemic due to its high transmission rate and quick dissemination.There have been numerous reports on the side effects of the COVID-19 immunization,with a focus on its negative effects.Clinical endocrinology is extremely interested in the endocrine issue that arises after receiving the COVID-19 vaccine.As was already mentioned,after receiving the COVID-19 vaccine,many clinical problems could occur.Additionally,there are some compelling reports on diabetes.After receiving the COVID-19 vaccine,a patient experienced hyperosmolar hyperglycemia state,a case of newly-onset type 2 diabetes.There has also been information on a potential connection between the COVID-19 vaccine and diabetic ketoacidosis.Common symptoms include thirst,polydipsia,polyuria,palpitations,a lack of appetite,and weariness.In extremely rare clinical circumstances,a COVID-19 vaccine recipient may develop diabetes complications such as hyperglycemia and ketoacidosis.In these circumstances,routine clinical care has a successful track record.It is advised to give vaccine recipients who are vulnerable to problems,such as those with type 1 diabetes as an underlying illness,extra attention.展开更多
In response to the paper on coronavirus disease 2019's effects on trauma throughput,elective care models should be modified.Concerns about the relevant factors and their potential therapeutic applications are brou...In response to the paper on coronavirus disease 2019's effects on trauma throughput,elective care models should be modified.Concerns about the relevant factors and their potential therapeutic applications are brought up and looked into.展开更多
This letter to editor discusses on the publication on adipocytokine profile in children with Kawasaki disease.Concerns on confounding factors are raised and discussed.
Outbreak of a new emerging disease is usually an important consideration in medicine and public health. In December 2019, a new emerging disease started in China and becomes the global concern in early January 2020[1,...Outbreak of a new emerging disease is usually an important consideration in medicine and public health. In December 2019, a new emerging disease started in China and becomes the global concern in early January 2020[1,2]. The disease, 2019-novel coronavirus(2019-nCoV) infection, already existed outside China and the importation of disease is the cause of emerging 2019-nCoV infections in new settings.展开更多
There are several tropical mosquito borne infections.Malaria and dengue are the two common mosquito infections that are very important and cause high morbidity and mortality for many patients around the world.Concurre...There are several tropical mosquito borne infections.Malaria and dengue are the two common mosquito infections that are very important and cause high morbidity and mortality for many patients around the world.Concurrent malaria and dengue infection is an important condition that is seldom reported.In this specific article,the author hereby summarizes on the topic of concurrent malaria and dengue infection.展开更多
Zika virus infection is the present problematic arboviral disease. Classically, this disease cause febrile illness and can result in low platelet count. However, there are some new obervations on atypical clinical pre...Zika virus infection is the present problematic arboviral disease. Classically, this disease cause febrile illness and can result in low platelet count. However, there are some new obervations on atypical clinical presentations of Zika virus infection that can make the diagnosis more difficult. The afebrile, asymptomatic and non-thrombocytopenic Zika virus infection can be seen in clinical practice and can lead to missed or delayed diagnosis.展开更多
The risk of dengue virus transmission via blood transfusion is confirmed.As a similar virus,the risk for the case of Zika virus should be mentioned.Here,the authors calculated for the risk of Zika virus transmission v...The risk of dengue virus transmission via blood transfusion is confirmed.As a similar virus,the risk for the case of Zika virus should be mentioned.Here,the authors calculated for the risk of Zika virus transmission via blood transmission referring to the previous data on the risk in case of dengue virus.展开更多
To the editor,1.Introduction to new H7N9 bird flu Influenza virus infection is an important group of respiratory infectious disease.Several groups of influenza viruses can cause human infections.However,in the recent ...To the editor,1.Introduction to new H7N9 bird flu Influenza virus infection is an important group of respiratory infectious disease.Several groups of influenza viruses can cause human infections.However,in the recent years,there are many newly emerging influenza infections,which have never been previously seen in human.Crossing species from animal to human lead展开更多
Pox is an important infection that can cause the acute illness with dermatological manifestation.Apart from the well-known pox infections,the emerging zoonotic pox infections become interesting new issue in infectious...Pox is an important infection that can cause the acute illness with dermatological manifestation.Apart from the well-known pox infections,the emerging zoonotic pox infections become interesting new issue in infectious medicine.In this short review,the acute illness which results from new important zoonotic pox infections such as monkeypox,cowpox,raccoon pox and buffalopox is discussed and summarized.展开更多
An important problem in management of the case with myasthenia gravis (MG) is the control of exacerbation. There are several possible causes of exacerbation of MG including the use of drug. Here, the authors report a ...An important problem in management of the case with myasthenia gravis (MG) is the control of exacerbation. There are several possible causes of exacerbation of MG including the use of drug. Here, the authors report a case of MG exacerbation and diarrhea associated with erythromycin treatment.展开更多
Hyperglycemia is an important finding in the diabetic patient with poor glycemic control.There are several possible causes of hyperglycemic.Here,the author presents an interesting case study on a female diabetic patie...Hyperglycemia is an important finding in the diabetic patient with poor glycemic control.There are several possible causes of hyperglycemic.Here,the author presents an interesting case study on a female diabetic patient presenting with hyperglycemic due to intake of crude tamarind herbal pill.General practitioner should realize that the use of alternative medicine can be a cause of unexplained hyperglycemic episode in diabetic patient.展开更多
Wuhan coronavirus infection is a new emerging disease that started in China and presently spread into many countries[1,2]. The disease is an acute illness with respiratory manifestation caused by 2019 novel coronaviru...Wuhan coronavirus infection is a new emerging disease that started in China and presently spread into many countries[1,2]. The disease is an acute illness with respiratory manifestation caused by 2019 novel coronavirus (2019-nCoV) as designated by the World Health Organization (WHO). Until the present, there is no specific antiviral treatment. For prevention, standard infection control is necessary. Similar to any new emerging infectious diseases, finding new vaccine against the virus is the hope. In vaccinology, the first step for finding new vaccine is identifying the epitope of the pathogen. Based on the new bioinformatics technology, the bioinformatics approach is useful for epitope finding. The good example is the previous epitope finding within emerging Zika virus molecule[3]. Based on the same technique as used in the previous study on Zika virus[3], the authors hereby report the primary data on epitope finding in Wuhan novel coronavirus.展开更多
In the present day,bioinfomiatics becomes the modern science with several advantages.Several new"omics"sciences have been introduced for a few years and those sciences can he applied in biomedical work.Here,...In the present day,bioinfomiatics becomes the modern science with several advantages.Several new"omics"sciences have been introduced for a few years and those sciences can he applied in biomedical work.Here,the author will summarize and discuss on important applications of omics studies in microbiology focusing on microbial pathogeny.It can be seen that genomics and proteinomics can be well used in this area of biomedical studies.展开更多
To the editor The present problematic outbreak in Africa is the Ebola virus infection among local population in the capital of Guinea.It becomes a great concern since the present outbreak(March to April 2014)is consid...To the editor The present problematic outbreak in Africa is the Ebola virus infection among local population in the capital of Guinea.It becomes a great concern since the present outbreak(March to April 2014)is considered to be the biggest outbreak,the first discovery of this viral infection[1].A high death rate can be seen.Severe diarrhea and bleeding can be seen in almost all cases and death rate is very high(about 75%).Focusing on the present outbreak,there are many considerations on this situation.First,this outbreak occurs in urban area insead of a remote rural area。展开更多
Zika virus infection is a new problematic virus infection that becomes the present public health problem. Now this mosquito borne infectious disease can be seen worldwide and can cause dengue-like infection. In additi...Zika virus infection is a new problematic virus infection that becomes the present public health problem. Now this mosquito borne infectious disease can be seen worldwide and can cause dengue-like infection. In addition, it can also induce transplacental infection and result in congenital neurological defect. To prevent this infection, there is still no specific vaccine. To find a new vaccine, finding epitope is the first step. Here, the authors report the study to find epitope within Zika virus molecule.According to this study, the appropriate epitopes can be seen. This is the fi rst world report on epitope finding for Zika virus. The data can be useful for further vaccine development.展开更多
This letter to editor discusses and describes Zika virus IgG seropositivity rate in canine sera from endemic area.This is the first world report and it raises an urgent concern on pet,zoonosis and reservoir host regar...This letter to editor discusses and describes Zika virus IgG seropositivity rate in canine sera from endemic area.This is the first world report and it raises an urgent concern on pet,zoonosis and reservoir host regarding Zika virus.展开更多
Sofosbuvir is a new antiviral drug that has been recommended for management of hepatitis C virus (HCV) for a few years. New researches support that sofosbuvir might he useful for the management of Zika virus infection...Sofosbuvir is a new antiviral drug that has been recommended for management of hepatitis C virus (HCV) for a few years. New researches support that sofosbuvir might he useful for the management of Zika virus infection. Based on the pharmacological activity, inhibiting the HCV RNA-dependent RNA polymerase (RdRp or NS5 protein). sofosbuvir is proposed for its effectiveness against Zika virus infection. Here, the authors used a mathematical modelling theoretical approach to predict the expected dosage of sofosbuvir for inhibiting Zika virus infection. Based on the modeling study, if sofosbuvir is assigned for management of Zika virus. infection, doubled dosage of the present dosage for hepatitis C management is recommended.展开更多
Zika virus infection is the present global medical problem.The disease appears in several countries around the world.The relationship between rainfall and occurrence of Zika virus infection was previously mentioned.He...Zika virus infection is the present global medical problem.The disease appears in several countries around the world.The relationship between rainfall and occurrence of Zika virus infection was previously mentioned.Here,the authors use the mathematical modeling technique to reappraise on the previous data on immunoreactivity rate of Zika virus,dengue virus and Ckikungunya virus in Thailand and the reported interrelationship between arboviral infections and rainfall in Thailand for constructing of the predicted pattern of Zika virus distribution in Thailand.This data can be a useful tool for further disease surveillance in this area.展开更多
Leishmaniasis is an important tropical vector-borne disease.This infection can be seen in tropical area and it is considered to be one of the most important vector-borne infections at present.The general situation of ...Leishmaniasis is an important tropical vector-borne disease.This infection can be seen in tropical area and it is considered to be one of the most important vector-borne infections at present.The general situation of the leishmaniasis in Thailand is hereby reviewed.Although Thailand is a tropical country,the leishmaniasis is not endemic but sporadic.The imported cases are documented in some literatures.The serious form of leishmaniasis,the visceral leishmaniasis is also detectable in Thailand.Also,the author performed an in depth literature review of the reports of bone marrow leishmaniasis,a specific kind of visceral leishmaniasis, in Thailand in order to summarize the characteristics of this infection among Thai patients. According to this review,there have been at least S reports in the literature of 6 cases of bone marrow leishmaniasis in the Thai population,of which no case was lethaL Concerning the clinical manifestations,all except had prolonged fever with unknown origin.From physical examination, all had hepatospienomegaly.The striking findings were active hemophagocytosis with increased proliferation of lymphoidplasma cell line in the bone marrow and amastigotes of Leishmania donovani was demonstrated.Considering the treatment,pantavalent antimony compound was used and the excellent improvement and complete recovery.Finally,the author also discussed on the importance of leishmaniasis in Thailand relating to the present globalization and good traveling system.展开更多
To the editor, I read with interest the recent report on ＂filiform needle acupuncture for poststroke depression＂ （Zhang et al., 2014）. Zhang et al. （2014） performed a meta-analysis and conclud- ed that ＂early ...To the editor, I read with interest the recent report on ＂filiform needle acupuncture for poststroke depression＂ （Zhang et al., 2014）. Zhang et al. （2014） performed a meta-analysis and conclud- ed that ＂early filiform needle acupuncture for poststroke depression can perfectly control depression：＇ In fact, the in- cluded meta-analysis might support the clinical effectiveness of filariform needle acupuncture for poststroke depression. However, there are several concerns. First, the hospital infection due to acupuncture manipulation with filiform is a big topic to be addressed. As Gang et al. （2012） noted, ＂aseptic technic principles aren＇t strictly followed; disinfection and isolation systems are unsound;展开更多
文摘An efficient coronavirus disease 2019(COVID-19)vaccine is urgently required to fight the pandemic due to its high transmission rate and quick dissemination.There have been numerous reports on the side effects of the COVID-19 immunization,with a focus on its negative effects.Clinical endocrinology is extremely interested in the endocrine issue that arises after receiving the COVID-19 vaccine.As was already mentioned,after receiving the COVID-19 vaccine,many clinical problems could occur.Additionally,there are some compelling reports on diabetes.After receiving the COVID-19 vaccine,a patient experienced hyperosmolar hyperglycemia state,a case of newly-onset type 2 diabetes.There has also been information on a potential connection between the COVID-19 vaccine and diabetic ketoacidosis.Common symptoms include thirst,polydipsia,polyuria,palpitations,a lack of appetite,and weariness.In extremely rare clinical circumstances,a COVID-19 vaccine recipient may develop diabetes complications such as hyperglycemia and ketoacidosis.In these circumstances,routine clinical care has a successful track record.It is advised to give vaccine recipients who are vulnerable to problems,such as those with type 1 diabetes as an underlying illness,extra attention.
文摘In response to the paper on coronavirus disease 2019's effects on trauma throughput,elective care models should be modified.Concerns about the relevant factors and their potential therapeutic applications are brought up and looked into.
文摘This letter to editor discusses on the publication on adipocytokine profile in children with Kawasaki disease.Concerns on confounding factors are raised and discussed.
文摘Outbreak of a new emerging disease is usually an important consideration in medicine and public health. In December 2019, a new emerging disease started in China and becomes the global concern in early January 2020[1,2]. The disease, 2019-novel coronavirus(2019-nCoV) infection, already existed outside China and the importation of disease is the cause of emerging 2019-nCoV infections in new settings.
文摘There are several tropical mosquito borne infections.Malaria and dengue are the two common mosquito infections that are very important and cause high morbidity and mortality for many patients around the world.Concurrent malaria and dengue infection is an important condition that is seldom reported.In this specific article,the author hereby summarizes on the topic of concurrent malaria and dengue infection.
文摘Zika virus infection is the present problematic arboviral disease. Classically, this disease cause febrile illness and can result in low platelet count. However, there are some new obervations on atypical clinical presentations of Zika virus infection that can make the diagnosis more difficult. The afebrile, asymptomatic and non-thrombocytopenic Zika virus infection can be seen in clinical practice and can lead to missed or delayed diagnosis.
文摘The risk of dengue virus transmission via blood transfusion is confirmed.As a similar virus,the risk for the case of Zika virus should be mentioned.Here,the authors calculated for the risk of Zika virus transmission via blood transmission referring to the previous data on the risk in case of dengue virus.
文摘To the editor,1.Introduction to new H7N9 bird flu Influenza virus infection is an important group of respiratory infectious disease.Several groups of influenza viruses can cause human infections.However,in the recent years,there are many newly emerging influenza infections,which have never been previously seen in human.Crossing species from animal to human lead
文摘Pox is an important infection that can cause the acute illness with dermatological manifestation.Apart from the well-known pox infections,the emerging zoonotic pox infections become interesting new issue in infectious medicine.In this short review,the acute illness which results from new important zoonotic pox infections such as monkeypox,cowpox,raccoon pox and buffalopox is discussed and summarized.
文摘An important problem in management of the case with myasthenia gravis (MG) is the control of exacerbation. There are several possible causes of exacerbation of MG including the use of drug. Here, the authors report a case of MG exacerbation and diarrhea associated with erythromycin treatment.
文摘Hyperglycemia is an important finding in the diabetic patient with poor glycemic control.There are several possible causes of hyperglycemic.Here,the author presents an interesting case study on a female diabetic patient presenting with hyperglycemic due to intake of crude tamarind herbal pill.General practitioner should realize that the use of alternative medicine can be a cause of unexplained hyperglycemic episode in diabetic patient.
文摘Wuhan coronavirus infection is a new emerging disease that started in China and presently spread into many countries[1,2]. The disease is an acute illness with respiratory manifestation caused by 2019 novel coronavirus (2019-nCoV) as designated by the World Health Organization (WHO). Until the present, there is no specific antiviral treatment. For prevention, standard infection control is necessary. Similar to any new emerging infectious diseases, finding new vaccine against the virus is the hope. In vaccinology, the first step for finding new vaccine is identifying the epitope of the pathogen. Based on the new bioinformatics technology, the bioinformatics approach is useful for epitope finding. The good example is the previous epitope finding within emerging Zika virus molecule[3]. Based on the same technique as used in the previous study on Zika virus[3], the authors hereby report the primary data on epitope finding in Wuhan novel coronavirus.
文摘In the present day,bioinfomiatics becomes the modern science with several advantages.Several new"omics"sciences have been introduced for a few years and those sciences can he applied in biomedical work.Here,the author will summarize and discuss on important applications of omics studies in microbiology focusing on microbial pathogeny.It can be seen that genomics and proteinomics can be well used in this area of biomedical studies.
文摘To the editor The present problematic outbreak in Africa is the Ebola virus infection among local population in the capital of Guinea.It becomes a great concern since the present outbreak(March to April 2014)is considered to be the biggest outbreak,the first discovery of this viral infection[1].A high death rate can be seen.Severe diarrhea and bleeding can be seen in almost all cases and death rate is very high(about 75%).Focusing on the present outbreak,there are many considerations on this situation.First,this outbreak occurs in urban area insead of a remote rural area。
文摘Zika virus infection is a new problematic virus infection that becomes the present public health problem. Now this mosquito borne infectious disease can be seen worldwide and can cause dengue-like infection. In addition, it can also induce transplacental infection and result in congenital neurological defect. To prevent this infection, there is still no specific vaccine. To find a new vaccine, finding epitope is the first step. Here, the authors report the study to find epitope within Zika virus molecule.According to this study, the appropriate epitopes can be seen. This is the fi rst world report on epitope finding for Zika virus. The data can be useful for further vaccine development.
文摘This letter to editor discusses and describes Zika virus IgG seropositivity rate in canine sera from endemic area.This is the first world report and it raises an urgent concern on pet,zoonosis and reservoir host regarding Zika virus.
文摘Sofosbuvir is a new antiviral drug that has been recommended for management of hepatitis C virus (HCV) for a few years. New researches support that sofosbuvir might he useful for the management of Zika virus infection. Based on the pharmacological activity, inhibiting the HCV RNA-dependent RNA polymerase (RdRp or NS5 protein). sofosbuvir is proposed for its effectiveness against Zika virus infection. Here, the authors used a mathematical modelling theoretical approach to predict the expected dosage of sofosbuvir for inhibiting Zika virus infection. Based on the modeling study, if sofosbuvir is assigned for management of Zika virus. infection, doubled dosage of the present dosage for hepatitis C management is recommended.
文摘Zika virus infection is the present global medical problem.The disease appears in several countries around the world.The relationship between rainfall and occurrence of Zika virus infection was previously mentioned.Here,the authors use the mathematical modeling technique to reappraise on the previous data on immunoreactivity rate of Zika virus,dengue virus and Ckikungunya virus in Thailand and the reported interrelationship between arboviral infections and rainfall in Thailand for constructing of the predicted pattern of Zika virus distribution in Thailand.This data can be a useful tool for further disease surveillance in this area.
文摘Leishmaniasis is an important tropical vector-borne disease.This infection can be seen in tropical area and it is considered to be one of the most important vector-borne infections at present.The general situation of the leishmaniasis in Thailand is hereby reviewed.Although Thailand is a tropical country,the leishmaniasis is not endemic but sporadic.The imported cases are documented in some literatures.The serious form of leishmaniasis,the visceral leishmaniasis is also detectable in Thailand.Also,the author performed an in depth literature review of the reports of bone marrow leishmaniasis,a specific kind of visceral leishmaniasis, in Thailand in order to summarize the characteristics of this infection among Thai patients. According to this review,there have been at least S reports in the literature of 6 cases of bone marrow leishmaniasis in the Thai population,of which no case was lethaL Concerning the clinical manifestations,all except had prolonged fever with unknown origin.From physical examination, all had hepatospienomegaly.The striking findings were active hemophagocytosis with increased proliferation of lymphoidplasma cell line in the bone marrow and amastigotes of Leishmania donovani was demonstrated.Considering the treatment,pantavalent antimony compound was used and the excellent improvement and complete recovery.Finally,the author also discussed on the importance of leishmaniasis in Thailand relating to the present globalization and good traveling system.
文摘To the editor, I read with interest the recent report on ＂filiform needle acupuncture for poststroke depression＂ （Zhang et al., 2014）. Zhang et al. （2014） performed a meta-analysis and conclud- ed that ＂early filiform needle acupuncture for poststroke depression can perfectly control depression：＇ In fact, the in- cluded meta-analysis might support the clinical effectiveness of filariform needle acupuncture for poststroke depression. However, there are several concerns. First, the hospital infection due to acupuncture manipulation with filiform is a big topic to be addressed. As Gang et al. （2012） noted, ＂aseptic technic principles aren＇t strictly followed; disinfection and isolation systems are unsound;
