In this paper,we point out some practical obstacles arising in realization of compressional optical coherence elastography(OCE)that have not attracted sufficient attention previously.Specif-cally,we discuss(i)complica...In this paper,we point out some practical obstacles arising in realization of compressional optical coherence elastography(OCE)that have not attracted sufficient attention previously.Specif-cally,we discuss(i)complications in quantification of the Young modulus of tissues related to partial adhesion between the OCE probe and soft intervening reference layer sensor,(i)distorting influence of tisue suface curvature/corrugation on the subsurface strain distri-bution mapping,(ii)ways of signal-to-noise mtio(SNR)enhancement in OCE strain mapping when periodic averaging is not realized,and(iv)potentially significant infuence of tissue elastic nonlinearity on quantification of its stifness.Potential pnactical approaches to mitigate the effects of these complications are also described.展开更多
基金supported by the Russian Federation Government contract No.14.B25.31.0015supported by the Russian Foundation for Basic Research Grant No.16-02-00642Russian President grant for young scientists No.MK-6504.2016.2.
文摘In this paper,we point out some practical obstacles arising in realization of compressional optical coherence elastography(OCE)that have not attracted sufficient attention previously.Specif-cally,we discuss(i)complications in quantification of the Young modulus of tissues related to partial adhesion between the OCE probe and soft intervening reference layer sensor,(i)distorting influence of tisue suface curvature/corrugation on the subsurface strain distri-bution mapping,(ii)ways of signal-to-noise mtio(SNR)enhancement in OCE strain mapping when periodic averaging is not realized,and(iv)potentially significant infuence of tissue elastic nonlinearity on quantification of its stifness.Potential pnactical approaches to mitigate the effects of these complications are also described.
