Controlling fluid flow in capillaric circuits is a key requirement to increase their uptake for assay applications.Capillary action off-valves provide such functionality by pushing an occluding bubble into the channel...Controlling fluid flow in capillaric circuits is a key requirement to increase their uptake for assay applications.Capillary action off-valves provide such functionality by pushing an occluding bubble into the channel using a difference in capillary pressure.Previously,we utilized the binary switching mode of this structure to develop a powerful set of fundamental fluidic valving operations.In this work,we study the transistor-like qualities of the off-valve and provide evidence that these structures are in fact functionally complementary to electronic junction field effect transistors.In view of this,we propose the new term capillaric field effect transistor to describe these types of valves.To support this conclusion,we present a theoretical description,experimental characterization,and practical application of analog flow resistance control.In addition,we demonstrate that the valves can also be reopened.We show modulation of the flow resistance from fully open to pinch-off,determine the flow rate-trigger channel volume relationship and demonstrate that the latter can be modeled using Shockley's equation for electronic transistors.Finally,we provide a first example of how the valves can be opened and closed repeatedly.展开更多
基金The authors would like to thank Helen Devereux and Gary Turner of the Nanofabrication Laboratory at the University of Canterbury for technical support.Funding was provided by MBIE Grant UOCX1706.CM.acknowledges support in form of a JSPS Postdoctoral Fellowship for Research in Japan.V.N.acknowledges Rutherford Discovery Fellowship RDF-19-UOC-019for additional funding.
文摘Controlling fluid flow in capillaric circuits is a key requirement to increase their uptake for assay applications.Capillary action off-valves provide such functionality by pushing an occluding bubble into the channel using a difference in capillary pressure.Previously,we utilized the binary switching mode of this structure to develop a powerful set of fundamental fluidic valving operations.In this work,we study the transistor-like qualities of the off-valve and provide evidence that these structures are in fact functionally complementary to electronic junction field effect transistors.In view of this,we propose the new term capillaric field effect transistor to describe these types of valves.To support this conclusion,we present a theoretical description,experimental characterization,and practical application of analog flow resistance control.In addition,we demonstrate that the valves can also be reopened.We show modulation of the flow resistance from fully open to pinch-off,determine the flow rate-trigger channel volume relationship and demonstrate that the latter can be modeled using Shockley's equation for electronic transistors.Finally,we provide a first example of how the valves can be opened and closed repeatedly.
