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雷贝拉唑联合莫沙必利治疗胃食管反流所致慢性喉炎临床疗效及对血清IL-2、IL-4水平影响 被引量:1
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作者 孙哲 邓敏 +2 位作者 徐伟 方良春 秦燕子 《齐齐哈尔医学院学报》 2022年第11期1021-1024,共4页
目的探讨雷贝拉唑联合莫沙必利治疗胃食管反流所致慢性喉炎临床疗效及对血清白细胞介素-2(IL-2)、白细胞介素-4(IL-4)水平影响。方法选择2021年1—12月本院收治的86例胃食管反流所致慢性喉炎患者作为研究对象,按随机数表法分为对照组和... 目的探讨雷贝拉唑联合莫沙必利治疗胃食管反流所致慢性喉炎临床疗效及对血清白细胞介素-2(IL-2)、白细胞介素-4(IL-4)水平影响。方法选择2021年1—12月本院收治的86例胃食管反流所致慢性喉炎患者作为研究对象,按随机数表法分为对照组和观察组两组,每组各43例。对照组采用雷贝拉唑治疗,观察组在对照组基础上采用莫沙必利治疗,两组治疗时间均为2个月。评估两组患者的临床疗效、反流症状指数量表评分与反流体征量表评分,并且分析比较两组患者的炎症因子IL-2及IL-4水平、食管下括约肌压力及血清胃泌素水平。结果观察组总有效率为90.70%,高于对照组的72.09%(P<0.05);与治疗前相比,治疗后两组IL-2水平升高,且观察组高于对照组(P<0.05);治疗后两组IL-4水平降低,且观察组低于对照组(P<0.05);与治疗前相比,治疗后两组反流症状指数量表评分与反流体征量表评分均降低,且观察组低于对照组(P<0.05);与治疗前比较,两组食管下括约肌压力及血清胃泌素水平增加,且观察组优于对照组(P<0.05)。结论雷贝拉唑联合莫沙必利治疗胃食管反流所致慢性喉炎患者具有明显的临床疗效,可提高炎症因子IL-2水平和血清胃泌素水平,降低炎症因子IL-4水平,改善患者的食管下括约肌压力、反流和慢性喉炎的症状及体征,在临床研究中具有较高的实用价值。 展开更多
关键词 雷贝拉唑 莫沙必利 胃食管反流 慢性喉炎 反流症状指数量表评分 反流体征量表评分
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Eocene Basins on the SE Tibetan Plateau: Markers of Minor Offset along the Xuelongshan–Diancangshan–Ailaoshan Structural System 被引量:6
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作者 LIAO Cheng YANG Tiannan +10 位作者 XUE Chuandong LIANG Mingjuan XIN Di XIANG Kun JIANG Lili SHI Pengliang ZHU Wenbin wan liangchun TANG Jing YU Jing WU Pinglei 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2020年第4期1020-1041,共22页
The offset of geological bodies provides robust evidence of displacement along a fault or ductile shear zone. The amount of displacement along the Xuelongshan–Diancangshan–Ailaoshan structural system, southeastern T... The offset of geological bodies provides robust evidence of displacement along a fault or ductile shear zone. The amount of displacement along the Xuelongshan–Diancangshan–Ailaoshan structural system, southeastern Tibetan Plateau, is uncertain because of the lack of offset geological markers. This NNW–SSE-trending system is developed in three isolated metamorphic complexes and interjacent nonmetamorphosed rocks. They are expected to record similar post-Eocene strain, although their structural patterns should be distinct. Geological mapping in the area between the Xuelongshan and Diancangshan metamorphic complexes has revealed a small Eocene basin, the Madeng Basin, located to the west of the structural system. The sedimentary and volcanic successions of the Madeng Basin are comparable to those of the Jianchuan Basin, which is located to the east of the structural system. Zircon U–Pb geochronological and bulk geochemical data demonstrate that the volcanic rocks of both basins formed during 37–34 Ma and share the same geochemical features. These data suggest that the Madeng and Jianchuan basins previously constituted a single basin, with the distribution of high-K volcanic rocks in the basins defining an ENE–WSW-trending volcanic belt that shows a limited dextral offset of ≤20 km across the Xuelongshan–Diancangshan–Ailaoshan structural system. Therefore, the northern segment of the structural system records no evidence of large-scale lateral movement/displacement. The results suggest that the Indochina block, which is bounded by the Xuelongshan–Diancangshan–Ailaoshan structural system to the east and the Sagaing Fault to the west, has not extruded southward as a whole but rather has been deformed by pervasive crustal shortening. 展开更多
关键词 offset marker Eocene basin Xuelongshan–Diancangshan–Ailaoshan structural system southeastern Tibetan Plateau India–Eurasia collision
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