目的蛛网膜下腔出血(SAH)患者心电图异常频率高,研究确定任何特定的心电图异常是否与住院患者的不良结果相关。方法该研究从270例非创伤性SAH患者中选择145例作为研究对象。对所有SAH发病72h内的患者进行标准的体表心电图检查。根据出...目的蛛网膜下腔出血(SAH)患者心电图异常频率高,研究确定任何特定的心电图异常是否与住院患者的不良结果相关。方法该研究从270例非创伤性SAH患者中选择145例作为研究对象。对所有SAH发病72h内的患者进行标准的体表心电图检查。根据出院时住院死亡率或神经功能恶化程度(世界神经外科医师联合会,WFNS分级),将所有患者分为预后好组和预后不良组。结果不良结果(n=29)患者心率明显升高(93.52±22.23 vs 78.42±18,p<0.01),QTC延长(458.17±44.88 vs 436.89±43.46,p=0.027)。心电图异常的发生率较高,包括ST段(90%对44%,p<0.01)和左室肥大(28%对10%,p<0.03)。多重logistic回归发现ST异常(优势比2.811;95%可信区间1.014-7.789;p<0.05)、心率异常(优势比4.207;95%可信区间1.063-16.651;p<0.05)和WFNS分级(优势比4.741;95%可信区间1.949~11.531;p=0.001)是与住院不良预后相关的显著独立变量。结论ST段压低或抬高以及入院时心率异常,与住院SAH患者临床预后不良的风险增加密切相关。展开更多
An overview of the advances in studies on tribology of molecular deposition (MD) films is presented here to summarize the studies of nanofrictional properties, adhesion, wear and mechanical behavior, as well as the ...An overview of the advances in studies on tribology of molecular deposition (MD) films is presented here to summarize the studies of nanofrictional properties, adhesion, wear and mechanical behavior, as well as the molecular dynamics simulation of nanotribological properties of the film in the last decade. Some key research topics which need to be investigate further are addressed.展开更多
文摘目的蛛网膜下腔出血(SAH)患者心电图异常频率高,研究确定任何特定的心电图异常是否与住院患者的不良结果相关。方法该研究从270例非创伤性SAH患者中选择145例作为研究对象。对所有SAH发病72h内的患者进行标准的体表心电图检查。根据出院时住院死亡率或神经功能恶化程度(世界神经外科医师联合会,WFNS分级),将所有患者分为预后好组和预后不良组。结果不良结果(n=29)患者心率明显升高(93.52±22.23 vs 78.42±18,p<0.01),QTC延长(458.17±44.88 vs 436.89±43.46,p=0.027)。心电图异常的发生率较高,包括ST段(90%对44%,p<0.01)和左室肥大(28%对10%,p<0.03)。多重logistic回归发现ST异常(优势比2.811;95%可信区间1.014-7.789;p<0.05)、心率异常(优势比4.207;95%可信区间1.063-16.651;p<0.05)和WFNS分级(优势比4.741;95%可信区间1.949~11.531;p=0.001)是与住院不良预后相关的显著独立变量。结论ST段压低或抬高以及入院时心率异常,与住院SAH患者临床预后不良的风险增加密切相关。
基金the National Natural Science Foundation of China(Grant No.50575171)the National Basic Research Program of China(Grant No.2007CB607604)the Open Financial Fund of the State Key Laboratory of Tribology of Tsinghua University(Grant No.SKLT05-02).
文摘An overview of the advances in studies on tribology of molecular deposition (MD) films is presented here to summarize the studies of nanofrictional properties, adhesion, wear and mechanical behavior, as well as the molecular dynamics simulation of nanotribological properties of the film in the last decade. Some key research topics which need to be investigate further are addressed.