目的探讨经房间隔(AS)穿刺途径行介入封堵术治疗卵圆孔未闭(PFO)患者的安全性、有效性及预后。方法选取2016年8月-2017年12月衡水市人民医院心外科和武汉大学人民医院心内科经卵圆孔途径行介入封堵失败后改经AS穿刺途径完成PFO封堵的21...目的探讨经房间隔(AS)穿刺途径行介入封堵术治疗卵圆孔未闭(PFO)患者的安全性、有效性及预后。方法选取2016年8月-2017年12月衡水市人民医院心外科和武汉大学人民医院心内科经卵圆孔途径行介入封堵失败后改经AS穿刺途径完成PFO封堵的21例患者为AS穿刺组,取同期经卵圆孔途径行介入封堵术的30例PFO患者为对照组。观察PFO封堵术的有效封堵率、并发症、心脑血管事件的发生及预后情况。结果经导管PFO封堵术的成功率为100%。AS穿刺组的平均手术时间较对照组延长(78.0 min±13.4 min vs. 49.2 min±11.9 min)。2组患者术中及术后3 d的手术并发症发生率差异无统计学意义。术后随访1~18个月,AS穿刺组存在1例严重残余分流,有效封堵率为95.2%,与对照组间比较差异无统计学意义;2组间主要研究终点事件(卒中、周围血栓栓塞、死亡)和次要研究终点事件(新发房颤、心肌梗死、PFO相关的再次住院、出血)比较差异无统计学意义;Kaplan-Meier分析结果显示随访期间内2组间无缺血事件生存率差异无统计学意义。结论经房间隔穿刺和卵圆孔常规途径行PFO封堵术的临床疗效、并发症和无缺血事件的生存率比较无明显差异,可作为常规途径失败后较为安全的一种技术补充。展开更多
The study investigated the trend of extreme flood events in the Pearl River basin during 1951-2010. Stream flow data at 23 gauging stations were used for the study. The Pearson type III distribution was selected for t...The study investigated the trend of extreme flood events in the Pearl River basin during 1951-2010. Stream flow data at 23 gauging stations were used for the study. The Pearson type III distribution was selected for the flood frequency analysis. Results indicate that extreme flood events increase significantly in the Pearl River Basin since 1980. At the 23 gauging stations, there are 16 (70%) stations show positive (increasing) trends in 1981-2010. Most of the 16 stations are located along the West River and North River. While 7 (30%) stations show negative (decreasing) trends, and are found in the East River and the southeast region of the West River Basin.展开更多
文摘目的探讨经房间隔(AS)穿刺途径行介入封堵术治疗卵圆孔未闭(PFO)患者的安全性、有效性及预后。方法选取2016年8月-2017年12月衡水市人民医院心外科和武汉大学人民医院心内科经卵圆孔途径行介入封堵失败后改经AS穿刺途径完成PFO封堵的21例患者为AS穿刺组,取同期经卵圆孔途径行介入封堵术的30例PFO患者为对照组。观察PFO封堵术的有效封堵率、并发症、心脑血管事件的发生及预后情况。结果经导管PFO封堵术的成功率为100%。AS穿刺组的平均手术时间较对照组延长(78.0 min±13.4 min vs. 49.2 min±11.9 min)。2组患者术中及术后3 d的手术并发症发生率差异无统计学意义。术后随访1~18个月,AS穿刺组存在1例严重残余分流,有效封堵率为95.2%,与对照组间比较差异无统计学意义;2组间主要研究终点事件(卒中、周围血栓栓塞、死亡)和次要研究终点事件(新发房颤、心肌梗死、PFO相关的再次住院、出血)比较差异无统计学意义;Kaplan-Meier分析结果显示随访期间内2组间无缺血事件生存率差异无统计学意义。结论经房间隔穿刺和卵圆孔常规途径行PFO封堵术的临床疗效、并发症和无缺血事件的生存率比较无明显差异,可作为常规途径失败后较为安全的一种技术补充。
基金supported by National Basic Research Program of China (No. 2010CB428405)Special Public Sector Research Program of Ministry of Water Resources(No.201301040 and 201301070)+2 种基金National Natural Science Foundation of China (No. 41001012)Foundation forthe Author of National Excellent Doctoral Dissertation of China (No. 201161)Qing Lan Project and Program for New Century Excellent Talents in University
文摘The study investigated the trend of extreme flood events in the Pearl River basin during 1951-2010. Stream flow data at 23 gauging stations were used for the study. The Pearson type III distribution was selected for the flood frequency analysis. Results indicate that extreme flood events increase significantly in the Pearl River Basin since 1980. At the 23 gauging stations, there are 16 (70%) stations show positive (increasing) trends in 1981-2010. Most of the 16 stations are located along the West River and North River. While 7 (30%) stations show negative (decreasing) trends, and are found in the East River and the southeast region of the West River Basin.
