The epidemiologic characteristics of 631 infant pertussis cases 〈 12 months, which accounted for 57.42% of the total cases, were analyzed by descriptive epidemiology in Tianjin, between 2010 and 2015. The incidence o...The epidemiologic characteristics of 631 infant pertussis cases 〈 12 months, which accounted for 57.42% of the total cases, were analyzed by descriptive epidemiology in Tianjin, between 2010 and 2015. The incidence of infants was 104.66/100,000, which was 118 times higher than in other age groups (P 〈 0.001). The primary type of pertussis simultaneously presented in households was adult-to-infant (70.51%). The parents were identified as the source of infection in 80.18% of cases for infants. The positive rate of placental antibody transfer was 31.06% and 3.13% for 3-month-old infants. Infants presented the highest age-specific pertussis incidence. The most important reason was parents were the important sources of infection, and secondly the lower level of antibodies in neonates and the rapid waning of maternal antibody titer.展开更多
Objectives To evaluate the distribution by age and sex of serum high-sensitivity C-reactive protein(hsCRP)in an urban Chinese population and to provide a profile prediction for the risk of bacterial infection,inflamma...Objectives To evaluate the distribution by age and sex of serum high-sensitivity C-reactive protein(hsCRP)in an urban Chinese population and to provide a profile prediction for the risk of bacterial infection,inflammatory diseases,or tissue damages in the body.Methods Serum hsCRP was determined using the Roche Tina-quant immuno-turbidimetric assay on a Hitachi 7600–010 automatic biochemical analyzer(Roche Diagnostics)in 1,572 males and 1,800 females,including 78 pregnant women,who were derived from the National Health and Nutrition Survey in2010–2012.Results The average hsCRP concentration in urban China was 0.68 mg/L for males and 0.65 mg/L for females.Significant differences in hsCRP were found among different age groups(P<0.05).Monitoring results showed no significant differences among the 6–11,45–59,and≥60-year-old groups in the comparison of hsCRP between males and females in large cities.However,hsCRP concentration was significantly higher in men aged 12–17 and 18–44 years than in women.Conclusion The distribution of the hsCRP status of residents in large cities in China was influenced by age and gender,and the hsCRP levels of both sexes increased gradually with age.In addition,hsCRP concentration was higher in healthy pregnant women than in non-pregnant women.Basing on our results,we recommend that this parameter be included in future national and international screening for early detection of various illnesses.展开更多
目的针对高龄妊娠期糖尿病患者采取微信平台健康干预途径,观察其对高龄妊娠期糖尿病患者血糖、焦虑情绪、自我效能及母婴结局等的影响效果。方法随机选取210例妊娠期糖尿病孕妇为研究对象,分为研究组、常规组,分别给予微信平台健康干预...目的针对高龄妊娠期糖尿病患者采取微信平台健康干预途径,观察其对高龄妊娠期糖尿病患者血糖、焦虑情绪、自我效能及母婴结局等的影响效果。方法随机选取210例妊娠期糖尿病孕妇为研究对象,分为研究组、常规组,分别给予微信平台健康干预、常规健康干预途径,对照分析干预前后血糖水平、焦虑情绪、自我效能及母婴结局指标的变化。结果研究组患者干预前空腹血糖(FBG)、餐后2h血糖(2 h PBG)、糖化血红蛋白(Hb A1c)值与常规组比较差异无统计学意义(P>0.05),干预后研究组患者血糖指标明显低于常规组(P<0.05);干预后焦虑情绪评分方面,研究组患者明显低于常规组(P<0.05);干预后研究组患者密西根糖尿病管理评定量表(DCP)指标评估结果均明显高于常规组(P<0.05);妊娠结局指标中分娩孕周、产后血糖达标率、孕期体重超标率方面组间比较差异无统计学意义(P> 0.05),但阴道分娩、产后并发症率分娩组间差异有统计学意义(P<0.05),研究组患者新生儿不良结局指标明显低于常规组(P<0.05)。结论通过对高龄妊娠期糖尿病(GDM)患者实施微信平台健康干预途径,采取图片、视频、音频、文字等方式宣讲GDM健康知识,对控制血糖水平、缓解患者焦虑情绪有明显效果,提升自我效能并改善母婴结局,具有较高的临床推广应用价值。展开更多
基金supported by the Research Fund of Tianjin Health and Family Planning Commission 2015KY18Science and Technology Major Project of Chinese Preventive Medicine Association Q2017A1225
文摘The epidemiologic characteristics of 631 infant pertussis cases 〈 12 months, which accounted for 57.42% of the total cases, were analyzed by descriptive epidemiology in Tianjin, between 2010 and 2015. The incidence of infants was 104.66/100,000, which was 118 times higher than in other age groups (P 〈 0.001). The primary type of pertussis simultaneously presented in households was adult-to-infant (70.51%). The parents were identified as the source of infection in 80.18% of cases for infants. The positive rate of placental antibody transfer was 31.06% and 3.13% for 3-month-old infants. Infants presented the highest age-specific pertussis incidence. The most important reason was parents were the important sources of infection, and secondly the lower level of antibodies in neonates and the rapid waning of maternal antibody titer.
基金supported by the National Key Research and Develepment Program of China 2016YFD0400602。
文摘Objectives To evaluate the distribution by age and sex of serum high-sensitivity C-reactive protein(hsCRP)in an urban Chinese population and to provide a profile prediction for the risk of bacterial infection,inflammatory diseases,or tissue damages in the body.Methods Serum hsCRP was determined using the Roche Tina-quant immuno-turbidimetric assay on a Hitachi 7600–010 automatic biochemical analyzer(Roche Diagnostics)in 1,572 males and 1,800 females,including 78 pregnant women,who were derived from the National Health and Nutrition Survey in2010–2012.Results The average hsCRP concentration in urban China was 0.68 mg/L for males and 0.65 mg/L for females.Significant differences in hsCRP were found among different age groups(P<0.05).Monitoring results showed no significant differences among the 6–11,45–59,and≥60-year-old groups in the comparison of hsCRP between males and females in large cities.However,hsCRP concentration was significantly higher in men aged 12–17 and 18–44 years than in women.Conclusion The distribution of the hsCRP status of residents in large cities in China was influenced by age and gender,and the hsCRP levels of both sexes increased gradually with age.In addition,hsCRP concentration was higher in healthy pregnant women than in non-pregnant women.Basing on our results,we recommend that this parameter be included in future national and international screening for early detection of various illnesses.
文摘目的针对高龄妊娠期糖尿病患者采取微信平台健康干预途径,观察其对高龄妊娠期糖尿病患者血糖、焦虑情绪、自我效能及母婴结局等的影响效果。方法随机选取210例妊娠期糖尿病孕妇为研究对象,分为研究组、常规组,分别给予微信平台健康干预、常规健康干预途径,对照分析干预前后血糖水平、焦虑情绪、自我效能及母婴结局指标的变化。结果研究组患者干预前空腹血糖(FBG)、餐后2h血糖(2 h PBG)、糖化血红蛋白(Hb A1c)值与常规组比较差异无统计学意义(P>0.05),干预后研究组患者血糖指标明显低于常规组(P<0.05);干预后焦虑情绪评分方面,研究组患者明显低于常规组(P<0.05);干预后研究组患者密西根糖尿病管理评定量表(DCP)指标评估结果均明显高于常规组(P<0.05);妊娠结局指标中分娩孕周、产后血糖达标率、孕期体重超标率方面组间比较差异无统计学意义(P> 0.05),但阴道分娩、产后并发症率分娩组间差异有统计学意义(P<0.05),研究组患者新生儿不良结局指标明显低于常规组(P<0.05)。结论通过对高龄妊娠期糖尿病(GDM)患者实施微信平台健康干预途径,采取图片、视频、音频、文字等方式宣讲GDM健康知识,对控制血糖水平、缓解患者焦虑情绪有明显效果,提升自我效能并改善母婴结局,具有较高的临床推广应用价值。