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副流感病毒对不同宿主致病性研究进展 被引量:1
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作者 何民辉 李真光 +6 位作者 王凤雪 朱洪伟 张淑琴 孙娜 汪孟航 温永俊 武华 《动物医学进展》 北大核心 2017年第5期81-85,共5页
副流感病毒(PIV)广泛地存在于自然界,其基因型较多,宿主范围广泛,不仅引起人的呼吸道疾病,而且使牛,羊,犬等动物感染发病,给畜牧业生产造成较大的经济损失。论文就副流感病毒的病毒学基础、致病机制、引起不同宿主动物特别是牛、羊、犬... 副流感病毒(PIV)广泛地存在于自然界,其基因型较多,宿主范围广泛,不仅引起人的呼吸道疾病,而且使牛,羊,犬等动物感染发病,给畜牧业生产造成较大的经济损失。论文就副流感病毒的病毒学基础、致病机制、引起不同宿主动物特别是牛、羊、犬等的广泛感染流行情况进行综述,为副流感病毒致病机制的研究以及诊断和预防策略的提出提供理论依据。 展开更多
关键词 副流感病毒 宿主动物 致病机制
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The Strong Convergence Properties for Partial Sums of m-NA Random Variables 被引量:2
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作者 wang meng-hang PEI Wen-chen +2 位作者 ZHANG Yu-heng YING Han-lu wang Xue-jun 《Chinese Quarterly Journal of Mathematics》 2018年第2期172-180,共9页
In this paper, by the three series theorem of m-negatively associated(m-NA,in short) random variables and the truncation method of random variables, we mainly investigated the strong convergence properties for partial... In this paper, by the three series theorem of m-negatively associated(m-NA,in short) random variables and the truncation method of random variables, we mainly investigated the strong convergence properties for partial sums of m-NA random variables.In addition, the Khintchine-Kolmogorov convergence theorem and Kolmogorov-type strong law of large numbers for m-NA random variables are also obtained. The results obtained in the paper generalize some corresponding ones for independent random variables and some dependent random variables. 展开更多
关键词 m-NA random variables Three series theorem Strong convergence Kolmogorov-type strong law of large numbers
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Neuropilin-1与Furin:决定伪狂犬病毒毒力的关键宿主基因
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作者 CHEN MENG wang meng-hang SHEN XUE-GANG 《中国预防兽医学报》 CAS CSCD 北大核心 2022年第10期1132-1132,共1页
猪伪狂犬病病毒(Pseudorabies virus,PRV)是危害养猪业的重要动物传染病之一。猪是伪狂犬病毒的天然宿主。近年来,越来越多的证据表明PRV可实现跨种间传播感染人,对人类健康构成潜在的威胁,尤其是在2011年以后猪伪狂犬病毒变异毒株的爆... 猪伪狂犬病病毒(Pseudorabies virus,PRV)是危害养猪业的重要动物传染病之一。猪是伪狂犬病毒的天然宿主。近年来,越来越多的证据表明PRV可实现跨种间传播感染人,对人类健康构成潜在的威胁,尤其是在2011年以后猪伪狂犬病毒变异毒株的爆发。PRV完成生命周期的复制不仅依赖于病毒自身编码的关键蛋白,也依赖于重要的宿主蛋白来完成。因此,寻找与PRV编码蛋白相互作用的重要宿主蛋白对阐明PRV的发病机制以及抗病毒治疗至关重要。PRV gB是最保守的囊膜糖蛋白,与人单纯疱疹病毒1(HSV-1)的gB蛋白有50%的氨基酸序列同源性。 展开更多
关键词 伪狂犬病毒 动物传染病 囊膜糖蛋白 猪伪狂犬病病毒 变异毒株 养猪业 PRV 种间传播
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Effect of Exposing Low-Frequency Electric Fields on the Proliferative Capacity and Morphological Features of Olfactory Ensheathing Cells in vitro
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作者 wang meng-hang LI Ping FAN Yu-bo 《Chinese Journal of Biomedical Engineering(English Edition)》 2014年第1期7-11,共5页
Olfactory ensheathing cells(OECs) transplanted into the damaged spinal cord may be considered as a valuable remedy explorations for spinal cord repair. The proliferation of transplanted olfactory ensheathing cells dep... Olfactory ensheathing cells(OECs) transplanted into the damaged spinal cord may be considered as a valuable remedy explorations for spinal cord repair. The proliferation of transplanted olfactory ensheathing cells depends on various environmental factors and effective cues, which may include electrical fields(EFs). In this study, we investigated the proliferative capacity, morphologic alterations of olfactory ensheathing cells derived from neonate rat that occurd when exposed to two EFs of 20 Hz, 50 mV and20 Hz, 100 mV for 6 h. For both EF treatments, the MTT results revealed that the cellular proliferation of exposed group during the last 6 h of the experiment was statistically higher than that of control group. Then, we investigated morphological structure changes in the cells stained by Coomassie brilliant blue. Compared with control group, most of cells were present at intensively proliferating appearance including the microfilaments were long and thick and the accumulated appearance of cells. It is conceivable that electrical fields as a new approach may promote the growth and proliferation of OECs and may be engineered to control the survival of transplanted OECs in injured spinal cord.Although our results have been suggesting that EFs may be non-chemical strategies for cell proliferation, the fundamental mechanisms remain to be elucidated. 展开更多
关键词 嗅鞘细胞 增殖能力 低频电场 形态特征 考马斯亮蓝染色 体外 细胞形态结构 脊髓损伤
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