Objective The relationship between outdoor temperature and blood pressure(BP) has been inconclusive. We analyzed data from a prospective cohort study in northwestern China to investigate the effect of outdoor temperat...Objective The relationship between outdoor temperature and blood pressure(BP) has been inconclusive. We analyzed data from a prospective cohort study in northwestern China to investigate the effect of outdoor temperature on BP and effect modification by season.Methods A total of 32,710 individuals who participated in both the baseline survey and the first follow-up in 2011–2015 were included in the study. A linear mixed-effect model and generalized additive mixed model(GAMM) were applied to estimate the association between outdoor temperature and BP after adjusting for confounding variables.Results The mean differences in systolic blood pressure(SBP) and diastolic blood pressure(DBP)between summer and winter were 3.5 mm Hg and 2.75 mm Hg, respectively. After adjusting for individual characteristics, meteorological factors and air pollutants, a significant increase in SBP and DBP was observed for lag 06 day and lag 04 day, a 0.28 mm Hg(95% CI: 0.27–0.30) per 1 °C decrease in average temperature for SBP and a 0.16 mm Hg(95% CI: 0.15–0.17) per 1 °C decrease in average temperature for DBP, respectively. The effects of the average temperature on both SBP and DBP were stronger in summer than in other seasons. The effects of the average temperature on BP were also greater if individuals were older, male, overweight or obese, a smoker or drinker, or had cardiovascular diseases(CVDs), hypertension, and diabetes.Conclusions This study demonstrated a significant negative association between outdoor temperature and BP in a high-altitude environment of northwest China. Moreover, BP showed a significant seasonal variation. The association between BP and temperature differed by season and individuals' demographic characteristics(age, gender, BMI), unhealthy behaviors(smoking and alcohol consumption), and chronic disease status(CVDs, hypertension, and diabetes).展开更多
Air pollution has ever become a global major public health problem.Previous studies showed that air pollution is associated with excessive mortality and morbidity of respiratory disease[1-2].The extreme weather temper...Air pollution has ever become a global major public health problem.Previous studies showed that air pollution is associated with excessive mortality and morbidity of respiratory disease[1-2].The extreme weather temperature can impact human health and the thermal stresses can lead not only to direct deaths and illnesses,but also to aggravation of respiratory disease[3-4].Though the independent展开更多
In recent years, more attentions have been paid to the association between climate change and human health. Increasing and more variable global surface temperature is one of the key climatic change factors which have ...In recent years, more attentions have been paid to the association between climate change and human health. Increasing and more variable global surface temperature is one of the key climatic change factors which have been consistently reported about the effect on human health. So far, more researches have revealed that temperature lead not only to direct deaths and illnesses but also to aggravation of cardiovascular and respiratory diseases. Typically, the relationship between temperature and mortality or morbidity is V-, U-, or J- shaped, with optimum temperature corresponding to the lowest point in the temperature mortality curve.展开更多
Type 2 diabetes mellitus(T2DM)is a major noncommunicable chronic disease in the population and is a major threat to global public health.According to the International Diabetes Federation[1],there were at least 463 mi...Type 2 diabetes mellitus(T2DM)is a major noncommunicable chronic disease in the population and is a major threat to global public health.According to the International Diabetes Federation[1],there were at least 463 million patients with diabetes between the ages of 20 and 79 in 2019,and this number will rise to 700 million by 2045.Dyslipidemia is the most important factor that influences T2DM.At present,cross-sectional studies are mainly used to determine the correlation between single lipid index,lipid ratio,and T2DM and its complications[2].Few studies have focused on dyslipidemia and its aggregation patterns in relation to T2DM.展开更多
基金supported by the National Science Foundation of China Grant Number 41505095, 41705122,81673248the Fundamental Research Funds for the Central Universities in China Grant Number lzujbky-2018-69,lzujbky-2018-66。
文摘Objective The relationship between outdoor temperature and blood pressure(BP) has been inconclusive. We analyzed data from a prospective cohort study in northwestern China to investigate the effect of outdoor temperature on BP and effect modification by season.Methods A total of 32,710 individuals who participated in both the baseline survey and the first follow-up in 2011–2015 were included in the study. A linear mixed-effect model and generalized additive mixed model(GAMM) were applied to estimate the association between outdoor temperature and BP after adjusting for confounding variables.Results The mean differences in systolic blood pressure(SBP) and diastolic blood pressure(DBP)between summer and winter were 3.5 mm Hg and 2.75 mm Hg, respectively. After adjusting for individual characteristics, meteorological factors and air pollutants, a significant increase in SBP and DBP was observed for lag 06 day and lag 04 day, a 0.28 mm Hg(95% CI: 0.27–0.30) per 1 °C decrease in average temperature for SBP and a 0.16 mm Hg(95% CI: 0.15–0.17) per 1 °C decrease in average temperature for DBP, respectively. The effects of the average temperature on both SBP and DBP were stronger in summer than in other seasons. The effects of the average temperature on BP were also greater if individuals were older, male, overweight or obese, a smoker or drinker, or had cardiovascular diseases(CVDs), hypertension, and diabetes.Conclusions This study demonstrated a significant negative association between outdoor temperature and BP in a high-altitude environment of northwest China. Moreover, BP showed a significant seasonal variation. The association between BP and temperature differed by season and individuals' demographic characteristics(age, gender, BMI), unhealthy behaviors(smoking and alcohol consumption), and chronic disease status(CVDs, hypertension, and diabetes).
基金supported by the Gong-Yi Program of China Meteorological Administration(GYHY201106034)National Natural Science Foundation of China(41075103)
文摘Air pollution has ever become a global major public health problem.Previous studies showed that air pollution is associated with excessive mortality and morbidity of respiratory disease[1-2].The extreme weather temperature can impact human health and the thermal stresses can lead not only to direct deaths and illnesses,but also to aggravation of respiratory disease[3-4].Though the independent
基金supported by the Gong-Yi Program of China Meteorological Administration (GYHY201106034)the National Science & Technology Infrastructure Foundation of China (2005DKA32403)the National Key Project of the Scientific and Technical Supporting Programs (2012BAJ18B08)
文摘In recent years, more attentions have been paid to the association between climate change and human health. Increasing and more variable global surface temperature is one of the key climatic change factors which have been consistently reported about the effect on human health. So far, more researches have revealed that temperature lead not only to direct deaths and illnesses but also to aggravation of cardiovascular and respiratory diseases. Typically, the relationship between temperature and mortality or morbidity is V-, U-, or J- shaped, with optimum temperature corresponding to the lowest point in the temperature mortality curve.
基金the National Natural Science Foundation of China[Grant Number:41705122,41505095]。
文摘Type 2 diabetes mellitus(T2DM)is a major noncommunicable chronic disease in the population and is a major threat to global public health.According to the International Diabetes Federation[1],there were at least 463 million patients with diabetes between the ages of 20 and 79 in 2019,and this number will rise to 700 million by 2045.Dyslipidemia is the most important factor that influences T2DM.At present,cross-sectional studies are mainly used to determine the correlation between single lipid index,lipid ratio,and T2DM and its complications[2].Few studies have focused on dyslipidemia and its aggregation patterns in relation to T2DM.