Research progress of miRNA and chronic nonbacterial prostatitis

Chronic nonbacterial prostatitis(CNP),also the typeⅢprostatitis account for more than 90%of all patients with prostatitis.It has a long course of disease,easy to repeat,unknown pathogenesis and poor clinical efficacy.At present,some scholars at home and abroad have found that there is differential expression of microRNA(miRNA)in prostatic fluid of CNP patients or prostate tissue of CNP rat model.Intervention of miRNA expression can alleviate the symptoms and pharmacodynamics of CNP to a certain extent,which opens up a new way and direction for the pathogenesis and diagnosis and treatment of CNP.Therefore,this paper reviews the research progress of miRNA and CNP in recent years.

X射线小肠钡剂造影与CT小肠造影在克罗恩病临床诊断效果的比较研究

目的:分析X射线小肠钡剂造影与CT小肠造影在克罗恩病(CD)临床诊断中的应用及其对诊断肠壁增厚及肠外并发症的应用价值。方法:回顾性选取医院收治的79例CD患者资料,所有患者分别采用X射线小肠钡剂造影及腹部CT小肠造影两种不同检查方式,对比两种检查方式对患者裂隙状溃疡、卵石征、多节段性病变、肠壁增厚、强化增加、蜂窝织炎、炎性包块、腹腔囊肿等病变征象的差异。结果:X射线钡剂小肠造影的裂隙状溃疡和卵石征诊断检出率分别为51.90%和50.63%;CT小肠造影诊断检出率均为0.00%;其差异有统计学意义(x2=7.417,x2=7.295;P<0.05);两种检查方式对多节段性病变诊断的检出率比较,差异无统计学意义(x2=1.688,P>0.05);CT小肠造影检查对强化增加、蜂窝织炎、炎性包块和腹腔囊肿诊断的检出率高于X射线钡剂小肠造影;其差异均有统计学意义(x2=10.070,x2=7.173,x2=4.770,x2=6.161;P<0.05)。结论:X射线钡剂造影能较好的检出裂隙状溃疡与卵石征,但对肠壁增厚及肠外并发症无诊断能力。X射线钡剂造影与CT造影在CD临床诊断中各具优势,需结合两种检查方式的优势综合判定,最大程度改善患者治疗与预后。