"It is truth universally acknowledged that a single man in possession of a good fortune,must be in want of a wife." Almost two centuries later,the deep impression on readers left by the opening sentence of P..."It is truth universally acknowledged that a single man in possession of a good fortune,must be in want of a wife." Almost two centuries later,the deep impression on readers left by the opening sentence of Pride and Prejudice has not decreased because of their changing literary taste.Jane Austin,the author of Pride and Prejudice,was one of the famous realistic writers in English literature in the nineteenth century.Pride and Prejudice is Austin's representative work.There were no earthshaking events,no dreadful disasters,no sharp contradictions and no romantic legends in Authin's novels.Time and space were small in her novels.She wrote how a marriageable woman could find a satisfactory husband.She described many kinds of love and marriage of different women.She expressed her own original views of marriage in her works.In Pride and Prejudice Austin wrote four marriage types: ideal Elizabeth and Darcy,realistic Charlotte and Collins,felicitous Jane and Bingley,unhappy Lydiard Wickham.She pointed out emphatically economic consideration is the bonds of wedlock and love.She said marriage is not determined by property and family status.It is unwise to marry without money,but it is wrong to marry for money;the marriage settled by love is happy and ideal.The thesis explicates that Austin's view of marriage was progressive,advocated by her focus on the equality between men and women.She emphasized marriage should be of equal importance both by love and by economic consideration,but love plays the guiding role.She revealed the connotation of marriage.She also analyses the marriage value in the 18th-19th century.Her exposure is of great realistic significance to the society today.展开更多
Background Patients with decreased cardiac and renal function,as well as old age suffer from poor outcomes when undergoing cardiac surgery.The aim of this study was to evaluate the association of age,creatinine and ej...Background Patients with decreased cardiac and renal function,as well as old age suffer from poor outcomes when undergoing cardiac surgery.The aim of this study was to evaluate the association of age,creatinine and ejection fraction(ACEF)score with in-hospital prognosis of patients with the acute type A aortic dissection(ATAAD).Methods From September 2017 to June 2021,a total of 435 ATAAD patients undergoing open surgery repair were enrolled,and classified into low ACEF(ACEF score<0.91,n=286)and high ACEF group(ACEF score≥0.91,n=149)according to the optimal cutoff value of 0.91.Logistic regression analysis was performed to investigate the association between ACEF score with adverse events.Results Thirty-five(8.0%)patients were excluded and 94(21.6%)developed in-hospital major adverse clinical events(MACEs)during hospitalization.The in-hospital mortality in high ACEF group was significantly higher than in low ACEF group(13.4%vs.5.2%,P=0.003).The in-hospital MACE rate was also significantly higher in patients with high ACEF score(high ACEF group:27.5%vs.low ACEF group:18.5%,P=0.031).Multivariable logistic analysis revealed that ACEF score was an independent indicator for in-hospital mortality[odds ratio(OR):5.66,95%confidence interval(CI):1.43-22.48,P=0.014]and in-hospital MACEs(OR:3.44,95%CI:1.30-9.15,P=0.013).Conclusions Elevated ACEF score was an independent predictor for in-hospital mortality and MACEs in patients with ATAAD undergoing open surgery repair,which might provide additional risk stratification.展开更多
文摘"It is truth universally acknowledged that a single man in possession of a good fortune,must be in want of a wife." Almost two centuries later,the deep impression on readers left by the opening sentence of Pride and Prejudice has not decreased because of their changing literary taste.Jane Austin,the author of Pride and Prejudice,was one of the famous realistic writers in English literature in the nineteenth century.Pride and Prejudice is Austin's representative work.There were no earthshaking events,no dreadful disasters,no sharp contradictions and no romantic legends in Authin's novels.Time and space were small in her novels.She wrote how a marriageable woman could find a satisfactory husband.She described many kinds of love and marriage of different women.She expressed her own original views of marriage in her works.In Pride and Prejudice Austin wrote four marriage types: ideal Elizabeth and Darcy,realistic Charlotte and Collins,felicitous Jane and Bingley,unhappy Lydiard Wickham.She pointed out emphatically economic consideration is the bonds of wedlock and love.She said marriage is not determined by property and family status.It is unwise to marry without money,but it is wrong to marry for money;the marriage settled by love is happy and ideal.The thesis explicates that Austin's view of marriage was progressive,advocated by her focus on the equality between men and women.She emphasized marriage should be of equal importance both by love and by economic consideration,but love plays the guiding role.She revealed the connotation of marriage.She also analyses the marriage value in the 18th-19th century.Her exposure is of great realistic significance to the society today.
基金supported by the Science and Technology Planning Project of Guangzhou(No.2014y2-00052)。
文摘Background Patients with decreased cardiac and renal function,as well as old age suffer from poor outcomes when undergoing cardiac surgery.The aim of this study was to evaluate the association of age,creatinine and ejection fraction(ACEF)score with in-hospital prognosis of patients with the acute type A aortic dissection(ATAAD).Methods From September 2017 to June 2021,a total of 435 ATAAD patients undergoing open surgery repair were enrolled,and classified into low ACEF(ACEF score<0.91,n=286)and high ACEF group(ACEF score≥0.91,n=149)according to the optimal cutoff value of 0.91.Logistic regression analysis was performed to investigate the association between ACEF score with adverse events.Results Thirty-five(8.0%)patients were excluded and 94(21.6%)developed in-hospital major adverse clinical events(MACEs)during hospitalization.The in-hospital mortality in high ACEF group was significantly higher than in low ACEF group(13.4%vs.5.2%,P=0.003).The in-hospital MACE rate was also significantly higher in patients with high ACEF score(high ACEF group:27.5%vs.low ACEF group:18.5%,P=0.031).Multivariable logistic analysis revealed that ACEF score was an independent indicator for in-hospital mortality[odds ratio(OR):5.66,95%confidence interval(CI):1.43-22.48,P=0.014]and in-hospital MACEs(OR:3.44,95%CI:1.30-9.15,P=0.013).Conclusions Elevated ACEF score was an independent predictor for in-hospital mortality and MACEs in patients with ATAAD undergoing open surgery repair,which might provide additional risk stratification.