临泽县地处风力侵蚀类型区的“三北”戈壁沙漠区,具有我国北方水土流失的典型特征,截至2020年底,全县水土流失面积为1193.46 km 2,水土保持率56.51%,远低于全国平均水平,存在严重的水土流失现象。进入高质量发展新时代,临泽县水土保持...临泽县地处风力侵蚀类型区的“三北”戈壁沙漠区,具有我国北方水土流失的典型特征,截至2020年底,全县水土流失面积为1193.46 km 2,水土保持率56.51%,远低于全国平均水平,存在严重的水土流失现象。进入高质量发展新时代,临泽县水土保持面临新的挑战,在梳理水土保持现状的基础上,分析了粮食安全、生态安全、防洪安全、农村饮水安全对水土保持的需求,据此明确了临泽县水土保持高质量发展目标和趋势,即通过采取黑河湿地生态保护与恢复、防风固沙生态林网建设、生态清洁小流域系统化建设和健全完善水土保持基础支撑体系等发展对策,到2035年人为水土流失得到全面防治,全县水土保持率目标值达到57.63%。展开更多
Wnt信号通路通过调节许多组织的发育和体内平衡,控制胚胎发育和成体稳态,其信号异常不仅会造成发育缺陷,而且与多种癌症的发生密切相关。近年来,研究发现Wnt信号通路在骨肉瘤的发生发展及转移中扮演重要角色。分泌型卷曲相关蛋白1(secre...Wnt信号通路通过调节许多组织的发育和体内平衡,控制胚胎发育和成体稳态,其信号异常不仅会造成发育缺陷,而且与多种癌症的发生密切相关。近年来,研究发现Wnt信号通路在骨肉瘤的发生发展及转移中扮演重要角色。分泌型卷曲相关蛋白1(secreted frizzled-related protein 1,SFRP1)因部分结构与Wnt信号通路的卷曲蛋白受体(frizzled,FZD)高度同源而被认为是一类Wnt通路调节剂,调节骨肉瘤中的Wnt信号通路。本文就SFRP1-Wnt信号轴对骨肉瘤的调节作用进行综述。展开更多
The Beishan orogenic zone is a key area to understand evolution of the Central Asian Orogenic Belt that is an accretionary factory well-enough preserved in the Paleozoic. In early Paleozoic, the tectonic mélange ...The Beishan orogenic zone is a key area to understand evolution of the Central Asian Orogenic Belt that is an accretionary factory well-enough preserved in the Paleozoic. In early Paleozoic, the tectonic mélange zone containing the coherent unit and mélange unit is triggered by the complicated accretionary process of the Beishan area. The early Paleozoic tectonic evolution of the Beishan orogenic zone is investigated in this study using sedimentology and stratigraphic correlations of the lowe Paleozoic deposits. From the Cambrian to the middle Ordovician, this region was characterized by geographically extensive, flat-bedded siliceous mudstone, indicating the existence of a large ocean basin. The oceanic plate entered the convergence phase in terms of the Wilson Circle during the Middle Ordovician, when numerous magmatic arcs formed along two opposite sides of the ocean. The magmatic arcs became the widest during the Silurian, suggesting that the Hongliuhe-Niujuanzi-Xichangjing Ocean(HNX;a southern branch of the Paleo Asian Ocean) was reduced to a small residual ocean in the central Beishan region by that time, and probably lasted till the Carboniferous or later by newly published data.展开更多
文摘临泽县地处风力侵蚀类型区的“三北”戈壁沙漠区,具有我国北方水土流失的典型特征,截至2020年底,全县水土流失面积为1193.46 km 2,水土保持率56.51%,远低于全国平均水平,存在严重的水土流失现象。进入高质量发展新时代,临泽县水土保持面临新的挑战,在梳理水土保持现状的基础上,分析了粮食安全、生态安全、防洪安全、农村饮水安全对水土保持的需求,据此明确了临泽县水土保持高质量发展目标和趋势,即通过采取黑河湿地生态保护与恢复、防风固沙生态林网建设、生态清洁小流域系统化建设和健全完善水土保持基础支撑体系等发展对策,到2035年人为水土流失得到全面防治,全县水土保持率目标值达到57.63%。
文摘Wnt信号通路通过调节许多组织的发育和体内平衡,控制胚胎发育和成体稳态,其信号异常不仅会造成发育缺陷,而且与多种癌症的发生密切相关。近年来,研究发现Wnt信号通路在骨肉瘤的发生发展及转移中扮演重要角色。分泌型卷曲相关蛋白1(secreted frizzled-related protein 1,SFRP1)因部分结构与Wnt信号通路的卷曲蛋白受体(frizzled,FZD)高度同源而被认为是一类Wnt通路调节剂,调节骨肉瘤中的Wnt信号通路。本文就SFRP1-Wnt信号轴对骨肉瘤的调节作用进行综述。
基金funded by the National Natural Science Foundation(No.41772107)the Geological Survey Program(No.DD20190370 and No.DD20190812)of the People's Republic of Chinathe National Key Research,Development Program of China(No.2016YFC0601005)。
文摘The Beishan orogenic zone is a key area to understand evolution of the Central Asian Orogenic Belt that is an accretionary factory well-enough preserved in the Paleozoic. In early Paleozoic, the tectonic mélange zone containing the coherent unit and mélange unit is triggered by the complicated accretionary process of the Beishan area. The early Paleozoic tectonic evolution of the Beishan orogenic zone is investigated in this study using sedimentology and stratigraphic correlations of the lowe Paleozoic deposits. From the Cambrian to the middle Ordovician, this region was characterized by geographically extensive, flat-bedded siliceous mudstone, indicating the existence of a large ocean basin. The oceanic plate entered the convergence phase in terms of the Wilson Circle during the Middle Ordovician, when numerous magmatic arcs formed along two opposite sides of the ocean. The magmatic arcs became the widest during the Silurian, suggesting that the Hongliuhe-Niujuanzi-Xichangjing Ocean(HNX;a southern branch of the Paleo Asian Ocean) was reduced to a small residual ocean in the central Beishan region by that time, and probably lasted till the Carboniferous or later by newly published data.