The title compounds(5 a and 5 b) were synthesized from dehydroabietic acid and characterized by MS, IR, NMR and elemental analysis. The crystal structure of compound 5 a was determined by single-crystal X-ray diffract...The title compounds(5 a and 5 b) were synthesized from dehydroabietic acid and characterized by MS, IR, NMR and elemental analysis. The crystal structure of compound 5 a was determined by single-crystal X-ray diffraction. The compound is of monoclinic system, space group P21 with a = 8.0860(16), b = 14.011(3), c = 9.799(2) ?, β = 106.31(3)?, Z = 2, V = 1065.5(4) ?3, Mr = 431.48, Dc = 1.345 Mg/m3, S = 1.002, μ = 0.099 mm-1, F(000) = 460, the final R = 0.0617 and wR = 0.1532 for 1397 observed reflections(I > 2σ(I)). The preliminary antibacterial assay showed that compound 5 a exhibited considerable inhibitory activity against Bacillus subtilis, Staphylococcus aureus and Methicillin-resistant S. aureus(MRSA) with MIC values of 2～8 μg/mL.展开更多
The title compound （C29H33NO2, 3） was synthesized and structurally characterized by elemental analysis, IR, MS, 1H- and 13C-NMR and single-crystal X-ray diffraction. The crystal is of monoclinic system, space group ...The title compound （C29H33NO2, 3） was synthesized and structurally characterized by elemental analysis, IR, MS, 1H- and 13C-NMR and single-crystal X-ray diffraction. The crystal is of monoclinic system, space group P21 with a = 14.428（3）, b = 7.3440（15）, c = 22.768（5） A, β = 95.17（3）°, V = 2402.7（8） A3, Z = 4, Mr = 427.56, Dc = 1.182 g/cm3, F （000） = 920, 2（MoKa） = 0.71073 A,μ = 0.073 mm-1, the final R= 0.0670 and wR= 0.1002 for 2437 reflections with I〉 2σ（I） Two crystallographically independent molecules with different conformations co-exist in the structure. The crystal structure is stabilized by intermolecular C-H…π interactions which make the molecules stack along the b axis. In addition, the preliminary cytotoxic assay showed that the title compound exhibited moderate inhibitory activity against KB and SW1116 cells.展开更多
The chemical composition of unpleasant smell, emitted from the production process of wood-plastic composites using Manchurian ash sawdust （Fraxinus mandschurica Rupr.） and polypropylene powder as the raw material, w...The chemical composition of unpleasant smell, emitted from the production process of wood-plastic composites using Manchurian ash sawdust （Fraxinus mandschurica Rupr.） and polypropylene powder as the raw material, was investigated. Wood sawdust and polypropylene powder were subjected to heat treatment to 290℃ during 8 min （the conditions were similar to those employed on an industrial scale）. The emitted compounds were collected and analyzed by gas chromatography-mass spectrometry （GC-MS）. The analytical results showed that the unpleasant smell was emitted from the pyrogenation of wood sawdust rather than from the polypropylene powder. Nine types of compounds （hydrocarbons, ethers, phenols, aldehydes, ketones, alcohols, acids and their derivatives, furan and its derivatives, and nitrogen-containing compounds） were collected in the gas phase during heating. Among those 126 components detected by GC-MS, 112 compounds were identified.展开更多
The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray dif...The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray diffractio is of monoclinic system,space group P21 with a=12.282(3),b=9.940(2),c=22.656(5)A,β=103.06(3)°,Z=2,V=2694.4(10)A^3,Mr=1182.95,Dc=1.458 Mg/m^3,S=1.000,μ=1.649 mm^-1,F(000)=1216,the final R=0.0791 and wR=0.1853 for 4098 observed reflections(Ⅰ>2σ(Ⅰ)).The preliminary antibacterial assay showed that compound 7g exhibits significant inhibitory against Bacillus subtilis,Staphylococcus aureus and Methicillin-resistant S.aureus(MRSA)with MIC values of 1.9~7.8μg/mL.展开更多
基金supported by the National Natural Science Foundation of China(31770616)the Natural Science Foundation of Jiangsu Province(BK201516)+2 种基金the Natural Science Foundation for Colleges and Universities in Jiangsu Province(17KJA220002)Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(PPZY2015C221)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘The title compounds(5 a and 5 b) were synthesized from dehydroabietic acid and characterized by MS, IR, NMR and elemental analysis. The crystal structure of compound 5 a was determined by single-crystal X-ray diffraction. The compound is of monoclinic system, space group P21 with a = 8.0860(16), b = 14.011(3), c = 9.799(2) ?, β = 106.31(3)?, Z = 2, V = 1065.5(4) ?3, Mr = 431.48, Dc = 1.345 Mg/m3, S = 1.002, μ = 0.099 mm-1, F(000) = 460, the final R = 0.0617 and wR = 0.1532 for 1397 observed reflections(I > 2σ(I)). The preliminary antibacterial assay showed that compound 5 a exhibited considerable inhibitory activity against Bacillus subtilis, Staphylococcus aureus and Methicillin-resistant S. aureus(MRSA) with MIC values of 2～8 μg/mL.
基金Supported by the National Natural Science Foundation of China(Project:31000273)Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
文摘The title compound （C29H33NO2, 3） was synthesized and structurally characterized by elemental analysis, IR, MS, 1H- and 13C-NMR and single-crystal X-ray diffraction. The crystal is of monoclinic system, space group P21 with a = 14.428（3）, b = 7.3440（15）, c = 22.768（5） A, β = 95.17（3）°, V = 2402.7（8） A3, Z = 4, Mr = 427.56, Dc = 1.182 g/cm3, F （000） = 920, 2（MoKa） = 0.71073 A,μ = 0.073 mm-1, the final R= 0.0670 and wR= 0.1002 for 2437 reflections with I〉 2σ（I） Two crystallographically independent molecules with different conformations co-exist in the structure. The crystal structure is stabilized by intermolecular C-H…π interactions which make the molecules stack along the b axis. In addition, the preliminary cytotoxic assay showed that the title compound exhibited moderate inhibitory activity against KB and SW1116 cells.
文摘The chemical composition of unpleasant smell, emitted from the production process of wood-plastic composites using Manchurian ash sawdust （Fraxinus mandschurica Rupr.） and polypropylene powder as the raw material, was investigated. Wood sawdust and polypropylene powder were subjected to heat treatment to 290℃ during 8 min （the conditions were similar to those employed on an industrial scale）. The emitted compounds were collected and analyzed by gas chromatography-mass spectrometry （GC-MS）. The analytical results showed that the unpleasant smell was emitted from the pyrogenation of wood sawdust rather than from the polypropylene powder. Nine types of compounds （hydrocarbons, ethers, phenols, aldehydes, ketones, alcohols, acids and their derivatives, furan and its derivatives, and nitrogen-containing compounds） were collected in the gas phase during heating. Among those 126 components detected by GC-MS, 112 compounds were identified.
基金supported by the National Natural Science Foundation of China(31770616 and 21601087)the Natural Science Foundation for Colleges and Universities in Jiangsu Province(17KJA220002)Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(PPZY2015C221)。
文摘The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray diffractio is of monoclinic system,space group P21 with a=12.282(3),b=9.940(2),c=22.656(5)A,β=103.06(3)°,Z=2,V=2694.4(10)A^3,Mr=1182.95,Dc=1.458 Mg/m^3,S=1.000,μ=1.649 mm^-1,F(000)=1216,the final R=0.0791 and wR=0.1853 for 4098 observed reflections(Ⅰ>2σ(Ⅰ)).The preliminary antibacterial assay showed that compound 7g exhibits significant inhibitory against Bacillus subtilis,Staphylococcus aureus and Methicillin-resistant S.aureus(MRSA)with MIC values of 1.9~7.8μg/mL.
