Ebola virus disease reemerged in Western Africa in 2014.Chinese Center for Disease Control and Prevention dispatched the first Ebola virus(EBOV)detection team to run newly established Sierra Leone-China Friendship B...Ebola virus disease reemerged in Western Africa in 2014.Chinese Center for Disease Control and Prevention dispatched the first Ebola virus(EBOV)detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory.The aims of study were to understand epidemiology,clinical manifestations and survival time of EBOV in patient's blood.A total of 913specimens were tested between March 11 and April20, 2015. EBOV positivity occurred in 7.37% of the blood and 0.53% in throat swabs.展开更多
In the present study we investigated the changes in miRNA levels inhuman rhinovirus 16(HRV16)-infected cells.A small RNA deep sequencing experiment was performed through next-generation sequencing.In total,53 differen...In the present study we investigated the changes in miRNA levels inhuman rhinovirus 16(HRV16)-infected cells.A small RNA deep sequencing experiment was performed through next-generation sequencing.In total,53 differentially expressed miRNAs were confirmed by RT-q PCR,including 37 known mi RNAs and 16 novel miRNAs.Interaction networks between differentially expressed miRNAs and their targets were established by mir DIP and Navigator.The prediction results showed that QKI.展开更多
基金supported by a China Mega-Project for Infectious Disease(2011ZX10004-101,2012ZX10004215)Major Program of the National Natural Science Foundation of China(81590763)a SKLID Development Grant(2012SKLID102)
文摘Ebola virus disease reemerged in Western Africa in 2014.Chinese Center for Disease Control and Prevention dispatched the first Ebola virus(EBOV)detection team to run newly established Sierra Leone-China Friendship Biological Safety Laboratory.The aims of study were to understand epidemiology,clinical manifestations and survival time of EBOV in patient's blood.A total of 913specimens were tested between March 11 and April20, 2015. EBOV positivity occurred in 7.37% of the blood and 0.53% in throat swabs.
文摘In the present study we investigated the changes in miRNA levels inhuman rhinovirus 16(HRV16)-infected cells.A small RNA deep sequencing experiment was performed through next-generation sequencing.In total,53 differentially expressed miRNAs were confirmed by RT-q PCR,including 37 known mi RNAs and 16 novel miRNAs.Interaction networks between differentially expressed miRNAs and their targets were established by mir DIP and Navigator.The prediction results showed that QKI.