Tuberculosis (TB) differs from many other infectious maladies in having particular social and geographic distributions. The disease was under control in developed nations and being brought under control in developin...Tuberculosis (TB) differs from many other infectious maladies in having particular social and geographic distributions. The disease was under control in developed nations and being brought under control in developing countries, as in China. TB has now been recognized as a public health threat and the incidence of TB is steadily rising. Though a lot of various hematological disorders have been described in TB, like anemia, leukocytosis and, the most frequently cited, pancytopenia, immune thrombocytopenic purpura (ITP) is extremely rare. When thrombocytopenia occurs in TB, it happens most commonly via non-immune pathways, as typically described in the context of pancytopenia that develops secondary to tuberculous granulomatous infiltration of the bone marrow, but a causal relationship between TB and immune thrombocvtonenia is extraordinarilv rare.展开更多
文摘Tuberculosis (TB) differs from many other infectious maladies in having particular social and geographic distributions. The disease was under control in developed nations and being brought under control in developing countries, as in China. TB has now been recognized as a public health threat and the incidence of TB is steadily rising. Though a lot of various hematological disorders have been described in TB, like anemia, leukocytosis and, the most frequently cited, pancytopenia, immune thrombocytopenic purpura (ITP) is extremely rare. When thrombocytopenia occurs in TB, it happens most commonly via non-immune pathways, as typically described in the context of pancytopenia that develops secondary to tuberculous granulomatous infiltration of the bone marrow, but a causal relationship between TB and immune thrombocvtonenia is extraordinarilv rare.