A novel 5-fluorouracil salt of 12-silicatungstic acid was synthesized and characterized by means of elemental analysis, IR, 1H NMR and 183W NMR spectra. The antitumor activity and toxicity of the complex have been eva...A novel 5-fluorouracil salt of 12-silicatungstic acid was synthesized and characterized by means of elemental analysis, IR, 1H NMR and 183W NMR spectra. The antitumor activity and toxicity of the complex have been evaluated both in vitro and in vivo.展开更多
A novel adenine(Ade) salt of 12-phosphotungstic acid was synthesized and characterized by elemental analyses,IR, 1H NMR,CV and single crystal X-ray diffraction. The compound crystallized in a triclinic system with...A novel adenine(Ade) salt of 12-phosphotungstic acid was synthesized and characterized by elemental analyses,IR, 1H NMR,CV and single crystal X-ray diffraction. The compound crystallized in a triclinic system with a space group P 1 and a =1.3108(3) nm, b =1.3515(3) nm,c =1.3870(3) nm, V =2.0217(7) nm 3,Z =1,R _1=0.0391,wR _2=0.0959. The structure unit of the complex was constructed from [HPW_ 12 ·O_ 40 ] -,(C_5H_6N_5) + and C_3H_7NO,which further extends to form a novel three-dimensional host-guest network via hydrogen-bonding interactions. The anti-tumor activity of the compound was examined in two human tumor cell lines in vitro .展开更多
文摘A novel 5-fluorouracil salt of 12-silicatungstic acid was synthesized and characterized by means of elemental analysis, IR, 1H NMR and 183W NMR spectra. The antitumor activity and toxicity of the complex have been evaluated both in vitro and in vivo.
文摘A novel adenine(Ade) salt of 12-phosphotungstic acid was synthesized and characterized by elemental analyses,IR, 1H NMR,CV and single crystal X-ray diffraction. The compound crystallized in a triclinic system with a space group P 1 and a =1.3108(3) nm, b =1.3515(3) nm,c =1.3870(3) nm, V =2.0217(7) nm 3,Z =1,R _1=0.0391,wR _2=0.0959. The structure unit of the complex was constructed from [HPW_ 12 ·O_ 40 ] -,(C_5H_6N_5) + and C_3H_7NO,which further extends to form a novel three-dimensional host-guest network via hydrogen-bonding interactions. The anti-tumor activity of the compound was examined in two human tumor cell lines in vitro .
