All‑Covalent Organic Framework Nanofilms Assembled Lithium‑Ion Capacitor to Solve the Imbalanced Charge Storage Kinetics

Free-standing covalent organic framework(COFs)nanofilms exhibit a remarkable ability to rapidly intercalate/de-intercalate Li^(+) in lithium-ion batteries,while simultaneously exposing affluent active sites in supercapacitors.The development of these nanofilms offers a promising solution to address the persistent challenge of imbalanced charge storage kinetics between battery-type anode and capacitor-type cathode in lithium-ion capacitors(LICs).Herein,for the first time,custom-made COFBTMB-TP and COFTAPB-BPY nanofilms are synthesized as the anode and cathode,respectively,for an all-COF nanofilm-structured LIC.The COFBTMB-TP nanofilm with strong electronegative–CF3 groups enables tuning the partial electron cloud density for Li^(+) migration to ensure the rapid anode kinetic process.The thickness-regulated cathodic COFTAPB-BPY nanofilm can fit the anodic COF nanofilm in the capacity.Due to the aligned 1D channel,2D aromatic skeleton and accessible active sites of COF nanofilms,the whole COFTAPB-BPY//COFBTMB-TP LIC demonstrates a high energy density of 318 mWh cm^(−3) at a high-power density of 6 W cm^(−3),excellent rate capability,good cycle stability with the capacity retention rate of 77%after 5000-cycle.The COFTAPB-BPY//COFBTMB-TP LIC represents a new benchmark for currently reported film-type LICs and even film-type supercapacitors.After being comprehensively explored via ex situ XPS,7Li solid-state NMR analyses,and DFT calculation,it is found that the COFBTMB-TP nanofilm facilitates the reversible conversion of semi-ionic to ionic C–F bonds during lithium storage.COFBTMB-TP exhibits a strong interaction with Li^(+) due to the C–F,C=O,and C–N bonds,facilitating Li^(+) desolation and absorption from the electrolyte.This work addresses the challenge of imbalanced charge storage kinetics and capacity between the anode and cathode and also pave the way for future miniaturized and wearable LIC devices.

Environmental characteristics of trace metals in seawater from the Ninety East Ridge in the Indian Ocean

The Ninety East Ridge in the Indian Ocean has complex and unique characteristics.The concentrations and distribution characteristics of 10 trace metals(V,Cr,Mn,Fe,Co,Ni,Cu,Cd,Pb,and U)in seawater from the Ninety East Ridge in the Indian Ocean were investigated.Results show that the average concentrations of different trace metals in all the collected seawater samples were 1.134μg/L for V,0.158μg/L for Cr,0.489μg/L for Mn,0.427μg/L for Fe,0.011μg/L for Co,0.395μg/L for Ni,0.403μg/L for Cu,0.097μg/L for Cd,0.139μg/L for Pb,and 3.470μg/L for U.Differences in the horizontal and vertical distributions of all measured trace metals were revealed,and the occurrence of high concentrations was nonuniform.In addition,the significant differences in the concentration distribution of different trace metals in seawater on both sides of the Ninety East Ridge present regional segmentation in the area for various trace metals in deep sea water.This study provided basic data for future investigations on the environmental and ecological impact of trace metals in the Indian Ocean and the potential water mass transport mechanism.

Microfluidic preparation of surfactant-free ultrafine DAAF with tunable particle size for insensitive initiator explosives

High purity and ultrafine DAAF(u-DAAF)is an emerging insensitive charge in initiators.Although there are many ways to obtain u-DAAF,developing a preparation method with stable operation,accurate control,good quality consistency,equipment miniaturization,and minimum manpower is an inevitable requirement to adapt to the current social technology development trend.Here reported is the microfluidic preparation of u-DAAF with tunable particle size by a passive swirling microreactor.Under the guidance of recrystallization growth kinetics and mixing behavior of fluids in the swirling microreactor,the key parameters(liquid flow rate,explosive concentration and crystallization temperature)were screened and optimized through screening experiments.Under the condition that no surfactant is added and only experimental parameters are controlled,the particle size of recrystallized DAAF can be adjusted from 98 nm to 785 nm,and the corresponding specific surface area is 8.45 m^(2)·g^(-1)to 1.33 m^(2)·g^(-1).In addition,the preparation method has good batch stability,high yield(90.8%-92.6%)and high purity(99.0%-99.4%),indicating a high practical application potential.Electric explosion derived flyer initiation tests demonstrate that the u-DAAF shows an initiation sensitivity much lower than that of the raw DAAF,and comparable to that of the refined DAAF by conventional spraying crystallization method.This study provides an efficient method to fabricate u-DAAF with narrow particle size distribution and high reproducibility as well as a theoretical reference for fabrication of other ultrafine explosives.

Construct a 3D microsphere of HMX/B/Al/PTFE to obtain the high energy and combustion reactivity

Metal(aluminum and boron)based energetic materials have been wildly applied in various fields including aerospace,explosives and micro-devices due to their high energy density.Unfortunately,the low combustion efficiency and reactivity of metal fuels,especially boron(B),severely limit their practical applications.Herein,multi-component 3D microspheres of HMX/B/Al/PTFE(HBA)have been designed and successfully prepared by emulsion and solvent evaporation method to achieve superior energy and combustion reactivity.The reactivity and energy output of HBA are systematically measured by ignitionburning test,constant-volume explosion vessel system and bomb calorimetry.Due to the increased interfacial contact and reaction area,HBA shows higher flame propagation rate,faster pressurization rate and larger combustion heat of 29.95 cm/s,1077 kPa/s,and 6164.43 J/g,which is 1.5 times,3.5 times,and 1.03 times of the physical mixed counterpart(HBA-P).Meanwhile,HBA also shows enhanced energy output and reactivity than 3D microspheres of HMX/B/PTFE(HB)resulting from the high reactivity of Al.The reaction mechanism of 3D microspheres is comprehensively investigated through combustion emission spectral and thermal analysis(TG-DSC-MS).The superior reactivity and energy of HBA originate from the surface etching of fluorine to the inert shell(Al_(2)O_(3) and B_(2)O_(3))and the initiation effect of Al to B.This work offers a promising approach to design and prepare high-performance energetic materials for the practical applications.

Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastoma

Ameloblastoma is a benign tumor characterized by locally invasive phenotypes,leading to facial bone destruction and a high recurrence rate.However,the mechanisms governing tumor initiation and recurrence are poorly understood.Here,we uncovered cellular landscapes and mechanisms that underlie tumor recurrence in ameloblastoma at single-cell resolution.Our results revealed that ameloblastoma exhibits five tumor subpopulations varying with respect to immune response(IR),bone remodeling(BR),tooth development(TD),epithelial development(ED),and cell cycle(CC)signatures.Of note,we found that CC ameloblastoma cells were endowed with stemness and contributed to tumor recurrence,which was dominated by the EZH2-mediated program.Targeting EZH2 effectively eliminated CC ameloblastoma cells and inhibited tumor growth in ameloblastoma patient-derived organoids.These data described the tumor subpopulation and clarified the identity,function,and regulatory mechanism of CC ameloblastoma cells,providing a potential therapeutic target for ameloblastoma.

Comparative study of cancer profiles between 2020 and 2022 using global cancer statistics(GLOBOCAN)

Background:The International Agency for Research on Cancer(IARC)released the latest estimates of the global burden of cancer.We present a comparison of cancer profiles between 2020 and 2022,leveraging data from the Global Cancer Statistics(GLOBOCAN).Methods:Cancer incidence and mortality data were sourced from two different years,2020 and 2022,in the GLOBOCAN database.We tracked changes in age-standardized incidence and mortality rates,as well as estimated numbers of new cancer cases and deaths of the 15 most common cancer types globally and in China between 2020 and 2022.Additionally,we conducted comparisons to assess alterations in the cancer burden and variations in mortality-to-incidence ratio(MIR)across different regions and countries for both 2020 and 2022.Results:Lung cancer remained the most common cancer and the leading cause of cancer death worldwide.The new cases of thyroid cancer witnessed a sharp increase in 2022.Conversely,the numbers of new cancer cases and deaths from stomach and esophageal cancer decreased significantly in 2022.The geographic distribution of cancer incidence and mortality across six continents in 2022 largely mirrored that of 2020.Higher Human Development Index(HDI)levels in countries corresponded with elevated rates of cancer incidence and mortality,consistent with the previous year.Among 185 countries or territories,China’s age-standardized incidence rate(ASIR)ranked 64th and its age-standardized mortality rate(ASMR)ranked 68th,aligning with global averages.Lung cancer continued to impose the greatest burden of incidence and mortality.Stomach,breast,and esophageal cancers showed declines in both case counts and ASIR.Noteworthy reductions in both ASMR and absolute mortality numbers were observed in liver,stomach,and esophageal cancers.The global MIR decreased from 0.516 in 2020 to 0.488 in 2022.MIR trends indicated an upward trajectory with decreasing HDI levels in both 2022 and 2020.While Canada,Germany,India,Italy,Japan,and the United Kingdom demonstrated increasing MIRs,China exhibited the most significant decrease,followed by Russia and the United States.Conclusions:The global landscape of cancer incidence and mortality in 2022 reflects ongoing trends observed in 2020.Cancer burdens vary notably across countries with differing socioeconomic statuses.Decreases in stomach,liver,and esophageal cancer cases and deaths signify progress in cancer control efforts.The decrease in the global MIRs highlights potential improvements in cancer management.

Metal-organic frameworks with mixed-ligands strategy as heterogeneous nucleation center to assist crystallization for efficient and stable perovskite solar cells

Deep-level defects and random oriented configuration in perovskite crystallization process would cause the nonradiative recombination and further affect the performance of perovskite solar cells(PSCs).Herein,two metal-organic frameworks(MOFs)with tunable Lewis-base passivation sites have been constructed(Cd-Httb and Cd-Httb-BDC,Httb=5-(4-(1H-1,2,4-triazole-1-yl)benzyl)-1h-tetrazole,BDC=1,4-dicarboxybenzene)to eliminate deep-level defects and simultaneously as nanostructured heterogeneous nucleation seed to assist the growth of large-grained perovskite films.Compared with the control and Cd-Httb,Cd-Httb-BDC designed with mix-ligands strategy exhibited the enhanced inducted effect on the crystallization and nucleation of high-quality perovskite films during annealing process.Consequently,the resultant Cd-Httb-BDC-modified device achieved higher power conversion efficiency(PCE)(22.18%)than the control(20.89%)and Cd-Httb(21.56%).Meanwhile,the unencapsulated Cd-Httb-BDC-modified device still maintained 90%of initial PCE after 1500 h in ambient conditions and exhibited enhanced thermal stability(85℃ in N_(2) atmosphere).This work presented a successful example of mixligands strategy on construction of high-quality MOF-assisted perovskite films for high-efficient and stable PSCs.

基于GoGCN的软件系统类交互关系预测

软件系统是一个复杂的人工制品,类之间的交互关系对软件质量有着潜在影响,如软件缺陷的级联传播效应就是一个典型.如何准确预测软件系统中类之间合理关系,优化设计结构是软件质量保障的一个开放问题.从软件网络观的视角,综合考虑软件系统中类与类之间关系(外部图),以及每个类内部方法之间关系(内部图),将软件系统抽象成一个图中图结构的软件网络,并在此基础上提出一种基于图中图卷积神经网络的类交互关系预测方法.首先对每个类内部图进行卷积得到类节点的初始特征,再通过外部图的卷积更新类节点的表征向量,最后通过计算类节点对的评估值进行交互预测.根据在6个Java开源项目上的实验结果显示,图中图结构有助于提高软件系统结构的表征能力,且所提方法与常规网络嵌入方法相比,AUC值和AP值的平均增长率超过5.5%.与此同时,和两种同行方法相比,AUC值和AP值的平均增长率分别在9.36%和5.22%以上.

Extremely Anisotropic Thermoelectric Properties of SnSe Under Pressure

SnSe has attracted extensive attention due to its ultralow thermal conductivity and excellent thermoelectric properties.In this work,pressure-induced thermoelectric properties of Pnma SnSe are investigated via first-principles calculations.We uncover distinct energy isosurfaces topology transition of conduction band by applying pressure.The newly created conduction band valley caused by pressure has a distinct anisotropic shape compared to the old one.Inducing pressure can greatly enhance the anisotropy of electronic transport properties of the n-type Pnma SnSe.Furthermore,the lattice thermal conductivity also exhibits anisotropic behavior under pressure due to a special collaged phonon mode.The pressure-induced lattice thermal conductivity along the a-axis shows a slower growth trend than that along the b-axis and c-axis.The optimal ZT value of the n-type Pnma SnSe along the a-axis can reach 1.64 at room temperature.These results would be helpful for designing the Pnma SnSe-based materials for the potential thermoelectric and valleytronic applications.

Characteristics of dissolved sugars in the Southern Yap Trench from sea surface to hadal zone

2,4,6-Tripyridine-s-triazine(TPTZ)spectrophotometric method was applied to determine the concentrations of dissolved monosaccharides(MCHO),polysaccharides(PCHO),and total carbohydrate(TCHO)in seawater samples collected from sea surface to hadal zone and sediment-seawater interface of the Southern Yap Trench in the Western Pacific Ocean.Results show that the concentrations of MCHO,PCHO,and TCHO ranged from 6.3 to 22.3μmol C/L,1.1 to 25.4μmol C/L,and 12.1 to 44.9μmol C/L,respectively,from the euphotic layer to the hadal zone of the trench.At different sampling stations,the concentrations of MCHO,PCHO,and TCHO in the seawater showed complex vertical variation characteristics,but the overall variation trends were decreasing with water depth.In the Southern Yap Trench,the maximum concentration of MCHO in the seawater appeared in the euphotic layer,and the minimum in the hadal zone.The maximum concentration of PCHO appeared in the euphotic layer,and the minimum in the bathypelagic layer.The water layer where the maxima and minima of the average concentration of TCHO appeared was consistent with that of PCHO.PCHO was the major component of TCHO in the seawater of the Southern Yap Trench.In the seawater from the sediment-seawater interface,the concentrations of MCHO,PCHO,and TCHO ranged from 8.4 to 10.6μmol C/L,3.8 to 5.8μmol C/L,and 12.2 to 15.2μmol C/L,respectively,and MCHO was the major component of TCHO.The key factors affecting the concentration and existing forms of dissolved sugars in the seawater of the Southern Yap Trench included photosynthesis,respiration,polysaccharide hydrolysis,adsorption and desorption of particulate matter,trench“funnel effect”,deep ocean currents,sediment resuspension,and etc.This study provided fundamental data about labile organic matter in abyss and hadal zone of marine environment,which is significant for further understanding of deep-sea organic carbon cycle.

Vertical variations and composition of dissolved free amino acid in the seawater of the Yap Trench in the western Pacific Ocean

The composition and concentration of dissolved free amino acid(DFAA)of seawater samples collected in May 2016 from the surface to the hadal zone of the northern region of the Yap Trench were analyzed by pre-column derivatization of o-phthalaldehyde.Results show that the average concentration of DFAA in the study area was 0.47±0.36μmol/L.In different sampling stations,the concentrations of DFAA with water depth showed complex variation patterns.At the sediment-seawater interface,the concentrations of DFAA in the western side of the trench were obviously higher than that in its eastern side.In the study area,there were no significant correlations between the concentrations of DFAA and the environmental parameters such as concentrations of chlorophyll a(Chl a),dissolved oxygen(DO),pH,and dissolved inorganic nitrogen(DIN),indicating that the concentrations of DFAA in seawater of the trench are affected by many factors,such as photosynthesis,respiration,temperature,pressure,illumination,and circulation.The dominant DFAA are similar in different water layers of sampling stations,including aspartic acid(Asp),glutamic acid(Glu),glycine(Gly),and serine(Ser).The composition of different amino acids,and the relative abundance of acidic,basic,and neutral amino acids might be related to the sources and consumption of various amino acids.Nine pairs of amino acids in the DFAA showed significantly positive relationship by correlation matrix analysis,suggesting that they might share similar biogeochemical processes.The degradation index(DI)of the DFAA in seawater of the Yap Trench could reflect the degradation,source,and freshness of DFAA in the trench to some extents.This is a preliminary study of amino acids from sea surface to hadal zone in the ocean,more works shall be done in different trenches to reveal their biogeochemical characte ristics in extreme marine environme nts.

一种噪声容忍的网络流量分类方法

针对传统基于机器学习的网络流量分类方法中样本标签的正确性会直接影响结果精度的问题,提出一种噪声容忍的网络流量分类方法。该方法基于深度残差网络的方法,首先,对网络流量数据进行归一化以及数据增强处理后映射成灰度图片,并对其样本标签进行不同程度的加噪;然后,基于Res2Net深度残差神经网络设计适用于网络流量噪声干扰下的维度模块,构造可以适用于流量标签噪声容忍的深度神经网络模型。基于公开数据集的实验结果表明,与传统的噪声容忍分类算法相比,基于改进的深度残差神经网络在不同噪声率下均提升了分类精度,并且在高噪声率下提升更为显著。

Canonical transient receptor potential channel 1 aggravates myocardial ischemia-and-reperfusion injury by upregulating reactive oxygen species

The canonical transient receptor potential channel(TRPC)proteins form Ca^(2+)-permeable cation channels that are involved in various heart diseases.However,the roles of specific TRPC proteins in myocardial ischemia/reperfusion(I/R)injury remain poorly understood.We observed that TRPC1 and TRPC6 were highly expressed in the area at risk(AAR)in a coronary artery ligation induced I/R model.Trpc1/mice exhibited improved cardiac function,lower serum Troponin T and serum creatine kinase level,smaller infarct volume,less fibrotic scars,and fewer apoptotic cells after myocardial-I/R than wild-type or Trpc6/mice.Cardiomyocyte-specific knockdown of Trpc1 using adeno-associated virus 9 mitigated myocardial I/R injury.Furthermore,Trpc1 deficiency protected adult mouse ventricular myocytes(AMVMs)and HL-1 cells from death during hypoxia/reoxygenation(H/R)injury.RNA-sequencing-based transcriptome analysis revealed differential expression of genes related to reactive oxygen species(ROS)generation in Trpc1/cardiomyocytes.Among these genes,oxoglutarate dehydrogenase-like(Ogdhl)was markedly downregulated.Moreover,Trpc1 deficiency impaired the calcineurin(CaN)/nuclear factorkappa B(NF-kB)signaling pathway in AMVMs.Suppression of this pathway inhibited Ogdhl upregulation and ROS generation in HL-1 cells under H/R conditions.Chromatin immunoprecipitation assays confirmed NF-kB binding to the Ogdhl promoter.The cardioprotective effect of Trpc1 deficiency was canceled out by overexpression of NF-kB and Ogdhl in cardiomyocytes.In conclusion,our findings reveal that TRPC1 is upregulated in the AAR following myocardial I/R,leading to increased Ca^(2+) influx into associated cardiomyocytes.Subsequently,this upregulates Ogdhl expression through the CaN/NF-kB signaling pathway,ultimately exacerbating ROS production and aggravating myocardial I/R injury.

Guideline for the diagnosis and treatment of rheumatoid arthritis with integrated traditional Chinese medicine and Western medicine to increase efficiency and reduce toxicity

Rheumatoid arthritis imposes a huge disease burden.Existing practice guidelines do not meet the needs of integrated traditional Chinese medicine and Western medicine in the treatment of rheumatoid arthritis.We established a guideline working group consists of a steering committee,a secretary group,an evidence evaluation group,a consensus group and a review group and developed a guideline following the guidance of the World Health Organization Handbook and the Chinese Medical Association.The guideline includes 35 recommendations which reached consensus by the two rounds Delphi surveys.These recommendations were formulated to address the following themes of most concern to clinician:diagnostic imaging,disease staging,traditional Chinese medicine syndromes,effectiveness and toxicity of integrated traditional Chinese medicine and Western medicine.

Octreotide reverses shock due to vasoactive intestinal peptide-secreting adrenal pheochromocytoma: A case report and review of literature

Vasoactive intestinal peptide-producing tumors （VIP-oma） usually originate in the pancreas and are chara-cterized by diarrhea, hypokalemia, and achlorhydria （WDHA syndrome）. In adults, nonpancreatic VIPoma is very rare. Herein, we report an unusual case of VIP-producing pheochromocytoma marked by persistent shock, fushing, and watery diarrhea and high sensitivity to octreotide. A 53-year-old woman was hospitalized for sudden-onset hypertension with convulsions, which then rapidly evolved to persistent shock, fushing, and watery diarrhea. Abdominal computed tomography indicated a left adrenal mass, accompanied by bleeding;and marked elevations of both plasma catecholamine and VIP concentrations were documented via laboratory testing. Surprisingly, all clinical symptoms responded swiftly to octreotide treatment. Once surgically treated, hormonal levels normalized in this patient, and the clinical symptoms dissipated. Postoperative pathological and immunohistopathological studies confrmed a VIP-secreting pheochromocytoma with strong, diffuse positivity for somatostatin receptor type 2. During a 6-mo follow-up period, she seemed in good health andwas symptom-free.

Locality Preserving Discriminant Projection for Speaker Verification

In this paper, a manifold subspace learning algorithm based on locality preserving discriminant projection (LPDP) is used for speaker verification. LPDP can overcome the deficiency of the total variability factor analysis and locality preserving projection (LPP). LPDP can effectively use the speaker label information of speech data. Through optimization, LPDP can maintain the inherent manifold local structure of the speech data samples of the same speaker by reducing the distance between them. At the same time, LPDP can enhance the discriminability of the embedding space by expanding the distance between the speech data samples of different speakers. The proposed method is compared with LPP and total variability factor analysis on the NIST SRE 2010 telephone-telephone core condition. The experimental results indicate that the proposed LPDP can overcome the deficiency of LPP and total variability factor analysis and can further improve the system performance.

城市再开发背景下的社区感知——基于内隐联想测验的研究

以广州市永庆坊为例,研究采用内隐联想测验法、问卷以及质性访谈相结合的方法,探究其改造前后社区相关主体的社区感知,旨在探讨社区空间变化背后相关主体的感知态度差异。研究结果揭示了社区感知的外显态度和内隐态度的分离效应,且外显态度表现的差异性强于内隐态度。参与者对永庆坊改造前后的连贯性和积极性存在外显感知态度的显著差异,在内隐态度结果上,参与者对永庆坊改造前后的连贯性和积极性并未存在显著差异。实验结果表明:物质层面的更新并非引起居民等主体对改造热议的根本原因,社区更新重点应关注利益主体对权利、参与权的诉求,关注其利益分配的合理性。诚然,社区改造规划中不仅应重视公众参与和调查,也应深入挖掘社区公众对于社区改造的内隐感知态度,以提高社区规划的效力。研究采用内隐联想测验的神经科学认知方法对景观感知的探讨,以期开拓人文地理学研究方法神经科学转向的新方向。

Speaker Verification Based on Log-Likelihood Score Normalization

Due to differences in the distribution of scores for different trials, the performance of a speaker verification system will be seriously diminished if raw scores are directly used for detection with a unified threshold value. As such, the scores must be normalized. To tackle the shortcomings of score normalization methods, we propose a speaker verification system based on log-likelihood normalization (LLN). Without a priori knowledge, LLN increases the separation between scores of target and non-target speaker models, so as to improve score aliasing of “same-speaker” and “different-speaker” trials corresponding to the same test speech, enabling better discrimination and decision capability. The experiment shows that LLN is an effective method of scoring normalization.

管理层盈利预测披露的偏误持续性研究

本文以2008～2014年自愿披露盈利预测信息的公司为样本，使用动态面板回归模型对自愿披露的管理层盈利预测的偏误持续性以及相应的分析师反应进行了实证研究。研究结果证实了A股上市公司管理层的自愿性盈利预测偏误确实存在持续性特征。在此基础上将分析师的预测偏误加入模型并进一步研究了证券分析师对管理层盈利预测偏误持续性的反应，研究结果发现证券分析师能观察到管理层的预测偏误特征并据此适度调整自身的盈利预测偏误。该研究结果为相关机构对预测性会计信息的提供者进行监管提供了相应借鉴，同时为预测性会计信息使用者运用盈利预测做出正确的判断与决策提供了解读方式。

伴体细胞型的纵膈恶性畸胎瘤病例报告

纵膈恶性畸胎瘤是占位于纵膈内的一种未分化成熟的畸胎瘤,临床上较少见。此类病患主要以胸闷,气短等因占位压迫邻近器官造成的症状为主诉。在影像学表现上很难与良性纵膈畸胎瘤区分,也不易与纵膈内其他常发肿瘤鉴别如胸腺瘤,支气管囊肿等。通过侵袭性检查(手术、穿刺活检)可明确,并在病理检验后确诊具体类型。近十年内有关纵膈恶性畸胎瘤的报告较少,特别是伴体细胞型的纵膈恶性畸胎瘤,其恶性程度高,治疗效果较差,病患预后不良,生存期很短。本病例报道一例伴体细胞型的纵膈恶性畸胎瘤,借此讨论此类肿瘤的综合治疗方案。