Secretory carcinoma is a rare breast cancer.We report a case of secretory carcinoma occurred in childhood.A 7-year-old girl had a history of a mass in the breast for 4 years.The tumor grew slowly and well circumscribe...Secretory carcinoma is a rare breast cancer.We report a case of secretory carcinoma occurred in childhood.A 7-year-old girl had a history of a mass in the breast for 4 years.The tumor grew slowly and well circumscribed,mimicking benign lesions on imaging.After breast lumpectomy,a diagnosis of secretory carcinoma was made based on its histological morphology,immunohistochemical reaction,and molecular profile.Herein,we report the process of diagnosis,and treatment of this rare case.展开更多
To date,due to increasing use of high-resolution computed tomography(CT)scans,more and more cases of minute pulmonary meningothelial-like nodules(MPMNs)were reported[1,2].Clinicopathological and histological character...To date,due to increasing use of high-resolution computed tomography(CT)scans,more and more cases of minute pulmonary meningothelial-like nodules(MPMNs)were reported[1,2].Clinicopathological and histological characteristics of this lesion have also been well described.The lesion appears as multiple nodules on CT image,and mainly observed in the patients,especially female,with malignant pulmonary tumors,such as adenocarcinoma of the lung[2].Histologically,MPMNs are comprised of arachnoid-like cells similar meningothelial cell in meningioma in the H&E slice.Recently,large pulmonary meningothelial-like nodule was reported[3].Here we report a case of MPMNs,which presented diffusely as multiple nodules in the lung field and some admixed with adenocarcinoma.Three year follow-up examinations by low-dose helical computed tomography scan after surgical partial resection of the cancer demonstrate that the MPMN lesions in the rest lung are not eliminated after targeted therapy of the lung cancer.展开更多
文摘Secretory carcinoma is a rare breast cancer.We report a case of secretory carcinoma occurred in childhood.A 7-year-old girl had a history of a mass in the breast for 4 years.The tumor grew slowly and well circumscribed,mimicking benign lesions on imaging.After breast lumpectomy,a diagnosis of secretory carcinoma was made based on its histological morphology,immunohistochemical reaction,and molecular profile.Herein,we report the process of diagnosis,and treatment of this rare case.
文摘To date,due to increasing use of high-resolution computed tomography(CT)scans,more and more cases of minute pulmonary meningothelial-like nodules(MPMNs)were reported[1,2].Clinicopathological and histological characteristics of this lesion have also been well described.The lesion appears as multiple nodules on CT image,and mainly observed in the patients,especially female,with malignant pulmonary tumors,such as adenocarcinoma of the lung[2].Histologically,MPMNs are comprised of arachnoid-like cells similar meningothelial cell in meningioma in the H&E slice.Recently,large pulmonary meningothelial-like nodule was reported[3].Here we report a case of MPMNs,which presented diffusely as multiple nodules in the lung field and some admixed with adenocarcinoma.Three year follow-up examinations by low-dose helical computed tomography scan after surgical partial resection of the cancer demonstrate that the MPMN lesions in the rest lung are not eliminated after targeted therapy of the lung cancer.
