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止痒外洗方联合氯雷他定治疗维持性血液透析患者皮肤瘙痒的疗效研究 被引量:33
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作者 王爱兵 胡文博 王宁宁 《中国现代医学杂志》 CAS 2018年第13期91-94,共4页
目的探讨止痒外洗方联合氯雷他定治疗维持性血液透析(MHD)患者皮肤瘙痒的疗效及安全性。方法选取2013年6月-2015年12月青海省人民医院收治的156例合并皮肤瘙痒的MHD患者为研究对象。MHD持续时间≥3个月,2~3次/周,且符合顽固性皮肤瘙痒... 目的探讨止痒外洗方联合氯雷他定治疗维持性血液透析(MHD)患者皮肤瘙痒的疗效及安全性。方法选取2013年6月-2015年12月青海省人民医院收治的156例合并皮肤瘙痒的MHD患者为研究对象。MHD持续时间≥3个月,2~3次/周,且符合顽固性皮肤瘙痒的诊断标准。排除合并严重的心、肺、肾等脏器疾病以及恶性肿瘤、皮肤疾病或其他导致皮肤瘙痒的代谢性疾病等。随机分为观察组和对照组,两组各78例,对照组患者给予氯雷他定,观察组给予止痒外洗方联合氯雷他定。比较两组治疗前后的视觉模拟评分(VAS)评分、改良Duo评分、匹兹堡睡眠质量指数问卷(PSQI)总分。结果两组治疗前的基线资料、VAS评分、改良Duo评分、PSQI总分比较,差异无统计学意义(P>0.05)。观察组治疗后6周的VAS评分、改良Duo评分、PSQI总分均低于同期的对照组(P<0.05)。在治疗期间,全部患者均未发生不良反应。结论止痒外洗方联合氯雷他定能显著缓解MHD患者的皮肤瘙痒症状,提高其睡眠质量,安全可靠,值得临床推广应用。 展开更多
关键词 止痒外洗方 瘙痒症 血液透析 尿毒症 氯雷他定
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腹膜透析腹膜炎的影响因素及短期预后分析 被引量:8
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作者 安玲 刘文花 +2 位作者 吉栋德 胡文博 王建荣 《中国现代医学杂志》 CAS 2020年第13期51-55,共5页
目的探讨腹膜透析腹膜炎的危险因素及短期预后。方法选取2017年6月-2018年7月青海省人民医院收治的腹膜透析患者的76例为研究对象,根据感染发生情况设为感染组46例和对照组30例。分析腹膜炎的相关危险因素,观察记录单发腹膜炎和多发腹... 目的探讨腹膜透析腹膜炎的危险因素及短期预后。方法选取2017年6月-2018年7月青海省人民医院收治的腹膜透析患者的76例为研究对象,根据感染发生情况设为感染组46例和对照组30例。分析腹膜炎的相关危险因素,观察记录单发腹膜炎和多发腹膜炎患者的治疗结局。结果76例腹膜透析患者,未发生腹膜炎患者30例(39.47%),46例(60.53%)患者感染腹膜炎56例次,其中1例感染4次,2例感染3次,4例感染2次;单因素分析,两组患者性别构成比、原发疾病、体重指数、白细胞计数、血红蛋白、透析液浓度、透析龄比较,差异无统计学意义(P>0.05);两组年龄、文化水平、民族、高糖透析液使用、C反应蛋白、白蛋白、血钾比较,差异有统计学意义(P<0.05);经多因素一般非条件Logistic分析,年龄[OR=1.893(95%CI:1.512,3.026)]、文化水平低下[OR=2.318(95%CI:1.389,3.225)]、民族[OR=0.724(95%CI:0.389,0.895)、C反应蛋白水平[OR=0.724(95%CI:0.389,0.895)]、白蛋白水平[OR=1.595(95%CI:1.090,2.335)]、血钾水平[OR=1.625(95%CI:1.079,2.449)]、高糖透析液使用[OR=1.186(95%CI:0.822,1.710)]均是腹膜炎的危险因素;单发腹膜炎缓解例数多于多发腹膜炎(P<0.05),多发腹膜炎患者拔管率及病死率高于单发性腹膜炎(P<0.05)。结论患者年龄、文化水平、民族、高糖透析液使用、C反应蛋白、白蛋白、血钾是腹膜透析发生腹膜炎的危险因素。多发性腹膜炎患者拔管率增加,预后差。临床根据患者自身情况进行干预可有效提高腹膜透析腹膜炎患者生存率。 展开更多
关键词 腹膜炎 腹膜透析 危险因素 预后
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Size effect of lattice material and minimum weight design 被引量:3
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作者 Jun Yan wen-bo hu +1 位作者 Zhen-hua Wang Zun-Yi Duan 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2014年第2期191-197,共7页
The size effects of microstructure of lattice materials on structural analysis and minimum weight design are studied with extented multiscale finite element method(EMsFEM) in the paper. With the same volume of base ... The size effects of microstructure of lattice materials on structural analysis and minimum weight design are studied with extented multiscale finite element method(EMsFEM) in the paper. With the same volume of base material and configuration, the structural displacement and maximum axial stress of micro-rod of lattice structures with different sizes of microstructure are analyzed and compared.It is pointed out that different from the traditional mathematical homogenization method, EMsFEM is suitable for analyzing the structures which is constituted with lattice materials and composed of quantities of finite-sized micro-rods.The minimum weight design of structures composed of lattice material is studied with downscaling calculation of EMsFEM under stress constraints of micro-rods. The optimal design results show that the weight of the structure increases with the decrease of the size of basic sub-unit cells. The paper presents a new approach for analysis and optimization of lattice materials in complex engineering constructions. 展开更多
关键词 Lattice material Light weight design Size ef-fect Extented multiscale finite element method
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Reflection Talbot Effect and Application
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作者 ZHONG-Mei huang wen-bo hu WEI-Qi huang 《贵州科学》 2013年第4期3-5,共3页
The reflection Talbot effect under the illumination of Gaussian spherical wave and plane wave is observed on 1D and 2D photonic crystal of silicon prepared by nanosecond laser. It is found that the distance between tw... The reflection Talbot effect under the illumination of Gaussian spherical wave and plane wave is observed on 1D and 2D photonic crystal of silicon prepared by nanosecond laser. It is found that the distance between two adjacent Talbot images increases lineally with increasing of image distance as well as amplification of Talbot images under the illumination of Gaussian spherical wave. The result of theory is coincident with that of experiment, which shows that selecting suitable wavefront shape of input field can enlarge the amplification rate and improve the resolution of Talbot imaging. The reflection Talbot effect will have a lot of good application in microscopy of micro-fabrication on silicon, such as detecting period structures of plasma on line of PLD fabricating. 展开更多
关键词 复合水凝胶 力学性能 吸水率 抑菌性
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