Pteropine orthoreovirus(PRV)is a nonenveloped double-stranded RNA(dsRNA)virus of the genus Orthoreovirus under the family Reoviridae.The PRV genome is composed of 10 dsRNA segments,including three large(L)segments,thr...Pteropine orthoreovirus(PRV)is a nonenveloped double-stranded RNA(dsRNA)virus of the genus Orthoreovirus under the family Reoviridae.The PRV genome is composed of 10 dsRNA segments,including three large(L)segments,three medium(M)segments,and four small(S)segments surrounded by an icosahedral capsid[1].展开更多
Pteropine orthoreovirus(PRV)is an emerging zoonotic respiratory virus with the potential to spill over from fruit bats to humans.PRV belongs to the family Reoviridae,whose name is derived from an abbreviation of"...Pteropine orthoreovirus(PRV)is an emerging zoonotic respiratory virus with the potential to spill over from fruit bats to humans.PRV belongs to the family Reoviridae,whose name is derived from an abbreviation of"respiratory enteric orphan".This family of viruses was initially not believed to cause diseases in humans and therefore was named an"orphan virus".PRV infections in humans are characterized by symptoms ranging from mild influenza-like illness to severe acute respiratory distress.展开更多
基金supported by the Fundamental Research Grant Scheme (FRGS)2019-1 (FRGS/1/2019/STG05/IMU/02/1)from the Ministry of Higher Education,Malaysia,International Medical University Research Grant (BP I-01-2018 (33))Pump priming Grant (F0013.54.04)University of Nottingham Malaysia。
文摘Pteropine orthoreovirus(PRV)is a nonenveloped double-stranded RNA(dsRNA)virus of the genus Orthoreovirus under the family Reoviridae.The PRV genome is composed of 10 dsRNA segments,including three large(L)segments,three medium(M)segments,and four small(S)segments surrounded by an icosahedral capsid[1].
基金This study was supported by International Medical University grants BMSI-2012(03)and BMSI-2018(04).
文摘Pteropine orthoreovirus(PRV)is an emerging zoonotic respiratory virus with the potential to spill over from fruit bats to humans.PRV belongs to the family Reoviridae,whose name is derived from an abbreviation of"respiratory enteric orphan".This family of viruses was initially not believed to cause diseases in humans and therefore was named an"orphan virus".PRV infections in humans are characterized by symptoms ranging from mild influenza-like illness to severe acute respiratory distress.
