Screening of crop genotypes with high K efficiency plays a fundamental role in understanding their physiological mechanisms. In this study, pot culture experiment was conducted to reveal the differences in uptake and ...Screening of crop genotypes with high K efficiency plays a fundamental role in understanding their physiological mechanisms. In this study, pot culture experiment was conducted to reveal the differences in uptake and use of K among 56 barley varieties. The coefficient of variation （CV） of K uptake （Ku） and K dry matter production index （KDMPI） of these varieties were higher than other indices and both Ku and KDMPI were significantly different among the barley varieties. Furthermore, Ku and KDMPI were positively correlated with dry matter weight （DMW） during the whole growth period; K use efficiency （KUE） and K harvesting index （KHI） were significantly related to dry grain weight （DGW） at maturing stage. Through cluster of these indices, Sandrime and AC Westech were found to be the most K-efficient and K-inefficient genotypes of barley, respectively. Significant differences were observed in uptake and use capacity of K between the two genotypes. During the whole growth period, Ku, K dry matter production efficiency （KDMPE）, KDMPI and DMW of the K- efficient genotype were found to be 1.5-1.8, 1.4-2.3, 2.1-3.9, and 1.7-2.1 times higher than those of the K-inefficient genotype, respectively, and at maturing stage, DWG, KUE, and KHI of efficient genotype were higher than those of the inefficient one. The results also showed that Sandrime was the most efficient candidate among the tested varieties for K efficiency and further studies should be conducted to investigate its physiological and biochemical characteristics.展开更多
目的评价高剂量乌司他丁(UTI)治疗大面积烧伤的有效性及安全性,为高剂量UTI治疗大面积烧伤提供更可靠的循证医学证据。方法检索PubMed、Web of Science、EMBASE、ClinicalTrials.gov、Cochrane Library、中国知网、中国生物医学数据库...目的评价高剂量乌司他丁(UTI)治疗大面积烧伤的有效性及安全性,为高剂量UTI治疗大面积烧伤提供更可靠的循证医学证据。方法检索PubMed、Web of Science、EMBASE、ClinicalTrials.gov、Cochrane Library、中国知网、中国生物医学数据库、万方、维普等中英文数据库,收集高剂量UTI治疗大面积烧伤的临床随机对照试验,检索范围为建库至2023年2月。根据Cochrane风险评估工具评估文献质量。使用Stata12.0、RevMan5.4软件进行Meta分析。结果共纳入24项研究,总计1451例患者,试验组730例,对照组721例。Meta分析结果显示,与传统治疗相比,高剂量UTI在治疗大面积烧伤的临床疗效方面更具优势,可以降低大面积烧伤患者的全身炎症反应综合征(SIRS)发生率(RR=0.61,95%CI:0.51~0.74,P<0.00001)、急性生理学与慢性健康状况评分表(APACHE)评分(MD=-4.90,95%CI:-7.52~-2.28,P=0.0002)、病死率(RR=0.54,95%CI:0.34~0.85,P=0.004)、TNF-α(SMD=-1.46,95%CI:-1.97~-0.95,P<0.00001)、谷丙转氨酶(ALT)(MD=-30.75,95%CI:-44.07~-17.43,P<0.00001)、血肌酐(SCR)(SMD=-2.02,95%CI:-3.05~-0.99,P=0.0001)、丙二醛(MDA)水平(MD=-3.44,95%CI:-3.87~-3.02,P<0.0001)、部分凝血活酶时间(aPTT)(MD=-3.42,95%CI:-5.78~-1.06,P=0.005);提升氧合指数(PaO 2/FiO 2)(MD=30.84,95%CI:4.36~57.32,P=0.02)、血小板计数(PLT)(MD=47.23,95%CI:39.35~55.10,P<0.00001);且不良事件发生少,Meta分析结果无统计学意义(RD=0.03,95%CI:-0.03~0.10,P=0.34)。结论高剂量UTI对大面积烧伤治疗效果良好,不良反应少,可下调患者炎症因子水平,降低SIRS发生率,改善ALT、SCR、APACHE评分、aPTT、MDA等脏器功能指标,从而降低患者病死率。展开更多
基金supported by the Natural Science Foundation of China (40901138)the Sichuan Youth Science & Technology Foundation (06ZQ026-020)+1 种基金the Youth Foundation of the Sichuan Education Bureau (07ZB063)the Key Project from Sichuan Education Bureau (07ZA059), China
文摘Screening of crop genotypes with high K efficiency plays a fundamental role in understanding their physiological mechanisms. In this study, pot culture experiment was conducted to reveal the differences in uptake and use of K among 56 barley varieties. The coefficient of variation （CV） of K uptake （Ku） and K dry matter production index （KDMPI） of these varieties were higher than other indices and both Ku and KDMPI were significantly different among the barley varieties. Furthermore, Ku and KDMPI were positively correlated with dry matter weight （DMW） during the whole growth period; K use efficiency （KUE） and K harvesting index （KHI） were significantly related to dry grain weight （DGW） at maturing stage. Through cluster of these indices, Sandrime and AC Westech were found to be the most K-efficient and K-inefficient genotypes of barley, respectively. Significant differences were observed in uptake and use capacity of K between the two genotypes. During the whole growth period, Ku, K dry matter production efficiency （KDMPE）, KDMPI and DMW of the K- efficient genotype were found to be 1.5-1.8, 1.4-2.3, 2.1-3.9, and 1.7-2.1 times higher than those of the K-inefficient genotype, respectively, and at maturing stage, DWG, KUE, and KHI of efficient genotype were higher than those of the inefficient one. The results also showed that Sandrime was the most efficient candidate among the tested varieties for K efficiency and further studies should be conducted to investigate its physiological and biochemical characteristics.
