目的·探索精神分裂症快感缺失的临床特征及其相关的影响因素。方法·2018年12月至2019年12月期间纳入71名精神分裂症患者及50名健康志愿者,使用阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)评估患者的精...目的·探索精神分裂症快感缺失的临床特征及其相关的影响因素。方法·2018年12月至2019年12月期间纳入71名精神分裂症患者及50名健康志愿者,使用阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)评估患者的精神症状,使用时间性愉快体验量表(Temporal Experience of Pleasure Scale,TEPS)和重复性成套神经心理状态测验(Repeatable Battery for the Assessment of Neuropsychological Status,RBANS)分别评估被试的快感缺失和认知功能。结果·TEPS评估结果显示,精神分裂症的期待性快感和消费性快感得分均低于健康对照(P=0.000)。逐步线性回归结果显示PANSS中的阴性症状得分(B=-0.895,P=0.002)和RBANS五因子中的延迟记忆得分(B=0.265,P=0.001)与精神分裂症快感缺失有关。结论·精神分裂症患者存在期待性和消费性快感缺失,而精神分裂症阴性症状和认知功能均能影响快感缺失程度。展开更多
With regard to blasting in deep rock masses,it is commonly thought that an increase in the in-situ stress will change the blast-induced rock crack propagation and ultimately affect rock fragmentation.However,little at...With regard to blasting in deep rock masses,it is commonly thought that an increase in the in-situ stress will change the blast-induced rock crack propagation and ultimately affect rock fragmentation.However,little attention has been given to the change in seismic wave radiation when the fractured zone changes with the in-situ stress.In this study,the influences of in-situ stress on blast-induced rock fracture and seismic wave radiation are numerically investigated by a coupled SPH-FEM simulation method.The results show that the change in blast-induced rock fracture with in-situ stress has a considerable effect on the seismic wave energy and composition.As the in-situ stress level increases,the size of the fractured zone is significantly reduced,and more explosion energy is transformed into seismic energy.A reduction in the size of the fractured zone(seismic wave source zone)results in a higher frequency content of the seismic waves.In a nonhydrostatic in-situ stress field,blast-induced cracks are most suppressed in the direction of the minimum in-situ stress,and thus the seismic waves generated in this direction have the highest energy density.In addition to P-waves,Swaves are also generated when a circular explosive is detonated in a nonhydrostatic in-situ stress field.The S-waves result from the asymmetrical release of rock strain energy due to the anisotropic blast-induced fracture pattern.展开更多
文摘目的·探索精神分裂症快感缺失的临床特征及其相关的影响因素。方法·2018年12月至2019年12月期间纳入71名精神分裂症患者及50名健康志愿者,使用阳性和阴性症状量表(Positive and Negative Syndrome Scale,PANSS)评估患者的精神症状,使用时间性愉快体验量表(Temporal Experience of Pleasure Scale,TEPS)和重复性成套神经心理状态测验(Repeatable Battery for the Assessment of Neuropsychological Status,RBANS)分别评估被试的快感缺失和认知功能。结果·TEPS评估结果显示,精神分裂症的期待性快感和消费性快感得分均低于健康对照(P=0.000)。逐步线性回归结果显示PANSS中的阴性症状得分(B=-0.895,P=0.002)和RBANS五因子中的延迟记忆得分(B=0.265,P=0.001)与精神分裂症快感缺失有关。结论·精神分裂症患者存在期待性和消费性快感缺失,而精神分裂症阴性症状和认知功能均能影响快感缺失程度。
基金Projects(51969015,U1765207)supported by the National Natural Science Foundation of ChinaProjects(20192ACB21019,20181BAB206047)supported by the Natural Science Foundation of Jiangxi Province,China。
文摘With regard to blasting in deep rock masses,it is commonly thought that an increase in the in-situ stress will change the blast-induced rock crack propagation and ultimately affect rock fragmentation.However,little attention has been given to the change in seismic wave radiation when the fractured zone changes with the in-situ stress.In this study,the influences of in-situ stress on blast-induced rock fracture and seismic wave radiation are numerically investigated by a coupled SPH-FEM simulation method.The results show that the change in blast-induced rock fracture with in-situ stress has a considerable effect on the seismic wave energy and composition.As the in-situ stress level increases,the size of the fractured zone is significantly reduced,and more explosion energy is transformed into seismic energy.A reduction in the size of the fractured zone(seismic wave source zone)results in a higher frequency content of the seismic waves.In a nonhydrostatic in-situ stress field,blast-induced cracks are most suppressed in the direction of the minimum in-situ stress,and thus the seismic waves generated in this direction have the highest energy density.In addition to P-waves,Swaves are also generated when a circular explosive is detonated in a nonhydrostatic in-situ stress field.The S-waves result from the asymmetrical release of rock strain energy due to the anisotropic blast-induced fracture pattern.