目的探讨养血清脑颗粒对脑梗死后抑郁症患者治疗效果的影响。方法将2016年6月-2019年6月本院纳入的100例脑梗死后抑郁症患者随机分为两组,对照组用帕罗西汀治疗;观察组在对照组基础上加养血清脑颗粒治疗,比较两组汉密斯顿抑郁量表(Hamil...目的探讨养血清脑颗粒对脑梗死后抑郁症患者治疗效果的影响。方法将2016年6月-2019年6月本院纳入的100例脑梗死后抑郁症患者随机分为两组,对照组用帕罗西汀治疗;观察组在对照组基础上加养血清脑颗粒治疗,比较两组汉密斯顿抑郁量表(Hamilton depression scale,HAMD)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、脑卒中神经功能缺损评分量表(national institute of health stroke scale,NIHSS)评分和皮质醇、去甲肾上腺素(noradrenaline,NE)、多巴胺(dopamine,DA)及5-羟色胺(5-hydroxytryptamine,5-HT)水平及不良反应。结果治疗后,两组NIHSS、HAMD、HAMA评分、皮质醇水平均较治疗前降低,观察组显著低于对照组(均P<0.05),两组5-HT、DA及NE均显著上升,观察组显著高于对照组(均P<0.05);两组不良反应率差异无统计学意义(P>0.05)。结论养血清脑颗粒联合帕罗西汀治疗脑梗死后抑郁患者效果显著,且不增加不良反应。展开更多
维修性验证是装备维修性工作的重要组成部分,平均修复时间(mean time to repair,MTTR)是维修性定量要求验证的主要参数。本文从国内外装备MTTR验证标准和手册发展情况以及装备MTTR验证常用方法两个方面综述了MTTR验证方法的国内外研究...维修性验证是装备维修性工作的重要组成部分,平均修复时间(mean time to repair,MTTR)是维修性定量要求验证的主要参数。本文从国内外装备MTTR验证标准和手册发展情况以及装备MTTR验证常用方法两个方面综述了MTTR验证方法的国内外研究进展。介绍了美国国防部、国际电工委员会和国内相关机构颁布的MTTR验证标准和手册的发展情况,分析了标准和手册中的MTTR验证方法。总结归纳了装备MTTR验证的常用方法及应用情况,包括基于实物装备的验证方法和基于虚拟现实的验证方法。在此基础上概括了装备MTTR验证方法的研究特点,展望了未来的研究方向,并给出了研究建议。展开更多
During maintainability demonstration,the maintenance time for complex systems consisting of mixed technologies generally conforms to a mixture distribution.However existing maintainability standards and guidance do no...During maintainability demonstration,the maintenance time for complex systems consisting of mixed technologies generally conforms to a mixture distribution.However existing maintainability standards and guidance do not explain explicitly how to deal with this situation.This paper develops a comprehensive maintainability demonstration method for complex systems with a mixed maintenance time distribution.First of all,a K-means algorithm and an expectation-maximization(EM)algorithm are used to partition the maintenance time data for all possible clusters.The Bayesian information criterion(BIC)is then used to choose the optimal model.After this,the clustering results for equipment are obtained according to their degree of membership.The degree of similarity for the maintainability of different kinds of equipment is then determined using the projection method.By using a Bootstrap method,the prior distribution is obtained from the maintenance time data for the most similar equipment.Then,a test method based on Bayesian theory is outlined for the maintainability demonstration.Finally,the viability of the proposed approach is illustrated by means of an example.展开更多
文摘目的探讨养血清脑颗粒对脑梗死后抑郁症患者治疗效果的影响。方法将2016年6月-2019年6月本院纳入的100例脑梗死后抑郁症患者随机分为两组,对照组用帕罗西汀治疗;观察组在对照组基础上加养血清脑颗粒治疗,比较两组汉密斯顿抑郁量表(Hamilton depression scale,HAMD)、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)、脑卒中神经功能缺损评分量表(national institute of health stroke scale,NIHSS)评分和皮质醇、去甲肾上腺素(noradrenaline,NE)、多巴胺(dopamine,DA)及5-羟色胺(5-hydroxytryptamine,5-HT)水平及不良反应。结果治疗后,两组NIHSS、HAMD、HAMA评分、皮质醇水平均较治疗前降低,观察组显著低于对照组(均P<0.05),两组5-HT、DA及NE均显著上升,观察组显著高于对照组(均P<0.05);两组不良反应率差异无统计学意义(P>0.05)。结论养血清脑颗粒联合帕罗西汀治疗脑梗死后抑郁患者效果显著,且不增加不良反应。
文摘维修性验证是装备维修性工作的重要组成部分,平均修复时间(mean time to repair,MTTR)是维修性定量要求验证的主要参数。本文从国内外装备MTTR验证标准和手册发展情况以及装备MTTR验证常用方法两个方面综述了MTTR验证方法的国内外研究进展。介绍了美国国防部、国际电工委员会和国内相关机构颁布的MTTR验证标准和手册的发展情况,分析了标准和手册中的MTTR验证方法。总结归纳了装备MTTR验证的常用方法及应用情况,包括基于实物装备的验证方法和基于虚拟现实的验证方法。在此基础上概括了装备MTTR验证方法的研究特点,展望了未来的研究方向,并给出了研究建议。
基金supported by the National Defense Pre-research Funds(9140A27010215JB34422)
文摘During maintainability demonstration,the maintenance time for complex systems consisting of mixed technologies generally conforms to a mixture distribution.However existing maintainability standards and guidance do not explain explicitly how to deal with this situation.This paper develops a comprehensive maintainability demonstration method for complex systems with a mixed maintenance time distribution.First of all,a K-means algorithm and an expectation-maximization(EM)algorithm are used to partition the maintenance time data for all possible clusters.The Bayesian information criterion(BIC)is then used to choose the optimal model.After this,the clustering results for equipment are obtained according to their degree of membership.The degree of similarity for the maintainability of different kinds of equipment is then determined using the projection method.By using a Bootstrap method,the prior distribution is obtained from the maintenance time data for the most similar equipment.Then,a test method based on Bayesian theory is outlined for the maintainability demonstration.Finally,the viability of the proposed approach is illustrated by means of an example.