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The temporal and spatial changes of actin cytoskeleton in the hippocampal CA1 neurons following transient global ischemia
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作者 Xiong Tianqing Huang Xinlei +2 位作者 wang ximyi Song Zhang Liang Jingyan 《解剖学杂志》 CAS 2021年第S01期114-114,共1页
Transient global ischemia usually results in delayed neuronal death in selective brain regions,prior to which a rapid loss of dendritic spines has been widely reported in these regions.Dendritic spines are characteriz... Transient global ischemia usually results in delayed neuronal death in selective brain regions,prior to which a rapid loss of dendritic spines has been widely reported in these regions.Dendritic spines are characterized by a highly branched meshwork of actin cytoskeleton(F-actin),which is extremely vulnerable to the ATP-depleted conditions such as hypoxia/ischemia.However,the ischemia-induced changes of F-actin are still not clarified in the vulnerable brain areas.This study was designed to examine the temporal and spatial alterations of F-actin in the CA1 subfield of rat hippocampus following reperfusion after global cerebral ischemia. 展开更多
关键词 ISCHEMIA DEATH CEREBRAL
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