The reaction of 5-(4-hydroxyphenyl)-10,15,20-triphenyl porphyrin with 2,6-dibromomethylpyridine and 4,4′-dicarboxyl-2,2′-bipyridine respectively gave 2,6-bis-[5,10,15-triphenyl-20-(4-phenoxymethyl)-porphyrin-yl]-pyr...The reaction of 5-(4-hydroxyphenyl)-10,15,20-triphenyl porphyrin with 2,6-dibromomethylpyridine and 4,4′-dicarboxyl-2,2′-bipyridine respectively gave 2,6-bis-[5,10,15-triphenyl-20-(4-phenoxymethyl)-porphyrin-yl]-pyridine(3) and 4,4′-di-[5,10,15-triphenyl-20-(p-phenoxycarbonyl)-porphyrin-yl]-2,2′-bipyridine (4). 5-[4-(4′- Bromobutoxy) phenyl]-10,15,20-triphenyl porphyrin reacted with 2,6-dihydroxymethylpyridine to give 2,6-bis-[5,10,15-triphenyl-20-(4-(p-phenoxy)-butoxymethyl)-porphyrin-yl]-pyridine(5). Those new compounds have been identified by1H NMR, IR, MS and UV-visible spectra, and elemental analysis. Key words bridged porphyrin - synthesis - structure characterization CLC number O 626.13 Foundation item: Supported by the National Natural Science Foundation of China (29972035)Biography: FU Shi-tao (1979-), male, Ph. D candidate, research direction: porphyrin chemistry.展开更多
Based on the judgement of fractional Br ow nian motion, this paper analyzes the radial rotating error of a precision rotor. The results indicate that the rotating error motion of the precision rot or is characterized...Based on the judgement of fractional Br ow nian motion, this paper analyzes the radial rotating error of a precision rotor. The results indicate that the rotating error motion of the precision rot or is characterized by basic fractional Brownian motions, i.e. randomicity, non -sequencity, and self-simulation insinuation to some extent. Also, this paper calculates the fractal box counting dimension of radial rotating error and judges that the rotor error motion is of stability, indicating that the motion range of the future track of the axes is relatively stable.展开更多
本文将三种空分压缩热的利用方式加以比较,包括有机朗肯–空分压缩热回收系统(ORC-ACS),有机朗肯–电驱动式蒸气压缩–空分压缩热回收系统(ORC-VCR-ACS),以及有机朗肯驱动式–蒸气压缩–空分压缩热系统(ORVC-ACS)。计算结果显示,ORVC-AC...本文将三种空分压缩热的利用方式加以比较,包括有机朗肯–空分压缩热回收系统(ORC-ACS),有机朗肯–电驱动式蒸气压缩–空分压缩热回收系统(ORC-VCR-ACS),以及有机朗肯驱动式–蒸气压缩–空分压缩热系统(ORVC-ACS)。计算结果显示,ORVC-ACS具有最高的节能性和经济性,其节能功率可达1723 k W,折合节约电量15.1 GWh/a,空压机节能率达7.5%。ORC-VCR-ACS次之,其最高节约功率约为1268 k W,ORC-ACS的节能功率最低,其最高节能功率约为783 k W。ORVC-ACS的最高净现值约为9.9千万元,折现回收周期小于3.2年,具有较高的经济效益。ORC-VCR-ACS和ORC-ACS的最高净现值和最大折现回收周期分别约为9.7千万元、3.4年和4.4千万元、4.8年。此外,三个系统每年最多可节约二氧化碳分别为10.8、11.4和4.9百万吨,显示出巨大的环境潜力。展开更多
目的研究多花黄精多糖对斑马鱼幼鱼2型糖尿病合并骨质疏松症的作用。方法用链脲佐菌素和泼尼松龙建立斑马鱼幼鱼2型糖尿病合并骨质疏松症模型,设置对照组、模型组、二甲双胍+依替膦酸二钠组和多花黄精多糖(60、120、240μg/mL)组,考察...目的研究多花黄精多糖对斑马鱼幼鱼2型糖尿病合并骨质疏松症的作用。方法用链脲佐菌素和泼尼松龙建立斑马鱼幼鱼2型糖尿病合并骨质疏松症模型,设置对照组、模型组、二甲双胍+依替膦酸二钠组和多花黄精多糖(60、120、240μg/mL)组,考察药物对斑马鱼早期发育毒性的影响;采用试剂盒测定各组幼鱼组织的糖含量;采用茜素红染色法考察各组斑马鱼头骨矿化面积和骨密度;采用qRT-PCR法检测各组斑马鱼骨质疏松相关基因Runx家族转录因子2b(Runx family transcription factor 2b,Runx2b)、Sp7转录因子(Sp7 transcription factor,Sp7)、I型胶原蛋白α2(collagen type Iα2,col1a2)、富含半胱氨酸的酸性分泌蛋白质因子(cysteine-rich acidic secreted protein,sparc)和维生素D受体b(vitamin D receptor b,vdrb)mRNA表达情况。结果显微注射链脲佐菌素和浸泡泼尼松龙能够提高幼鱼组织糖浓度,降低头骨矿化面积和骨密度。与模型组比较,多花黄精多糖显著上调斑马鱼幼鱼2型糖尿病合并骨质疏松症模型Runx2b、Sp7、vdrb、sparc、col1a2mRNA表达水平(P<0.05、0.01、0.001)。结论多花黄精多糖对斑马鱼幼鱼2型糖尿病合并骨质疏松症模型有较好的降血糖及抗骨质疏松症作用。展开更多
文摘The reaction of 5-(4-hydroxyphenyl)-10,15,20-triphenyl porphyrin with 2,6-dibromomethylpyridine and 4,4′-dicarboxyl-2,2′-bipyridine respectively gave 2,6-bis-[5,10,15-triphenyl-20-(4-phenoxymethyl)-porphyrin-yl]-pyridine(3) and 4,4′-di-[5,10,15-triphenyl-20-(p-phenoxycarbonyl)-porphyrin-yl]-2,2′-bipyridine (4). 5-[4-(4′- Bromobutoxy) phenyl]-10,15,20-triphenyl porphyrin reacted with 2,6-dihydroxymethylpyridine to give 2,6-bis-[5,10,15-triphenyl-20-(4-(p-phenoxy)-butoxymethyl)-porphyrin-yl]-pyridine(5). Those new compounds have been identified by1H NMR, IR, MS and UV-visible spectra, and elemental analysis. Key words bridged porphyrin - synthesis - structure characterization CLC number O 626.13 Foundation item: Supported by the National Natural Science Foundation of China (29972035)Biography: FU Shi-tao (1979-), male, Ph. D candidate, research direction: porphyrin chemistry.
文摘Based on the judgement of fractional Br ow nian motion, this paper analyzes the radial rotating error of a precision rotor. The results indicate that the rotating error motion of the precision rot or is characterized by basic fractional Brownian motions, i.e. randomicity, non -sequencity, and self-simulation insinuation to some extent. Also, this paper calculates the fractal box counting dimension of radial rotating error and judges that the rotor error motion is of stability, indicating that the motion range of the future track of the axes is relatively stable.
基金国家重点研发计划项目(No.2021YFE0112500)国家自然科学基金项目(No.52106029)The European Union’s Horizon 2020 research and innovation programme under the Marie Sk?odowska-Curie grant agreement(No.10100797)。
文摘本文将三种空分压缩热的利用方式加以比较,包括有机朗肯–空分压缩热回收系统(ORC-ACS),有机朗肯–电驱动式蒸气压缩–空分压缩热回收系统(ORC-VCR-ACS),以及有机朗肯驱动式–蒸气压缩–空分压缩热系统(ORVC-ACS)。计算结果显示,ORVC-ACS具有最高的节能性和经济性,其节能功率可达1723 k W,折合节约电量15.1 GWh/a,空压机节能率达7.5%。ORC-VCR-ACS次之,其最高节约功率约为1268 k W,ORC-ACS的节能功率最低,其最高节能功率约为783 k W。ORVC-ACS的最高净现值约为9.9千万元,折现回收周期小于3.2年,具有较高的经济效益。ORC-VCR-ACS和ORC-ACS的最高净现值和最大折现回收周期分别约为9.7千万元、3.4年和4.4千万元、4.8年。此外,三个系统每年最多可节约二氧化碳分别为10.8、11.4和4.9百万吨,显示出巨大的环境潜力。
文摘目的研究多花黄精多糖对斑马鱼幼鱼2型糖尿病合并骨质疏松症的作用。方法用链脲佐菌素和泼尼松龙建立斑马鱼幼鱼2型糖尿病合并骨质疏松症模型,设置对照组、模型组、二甲双胍+依替膦酸二钠组和多花黄精多糖(60、120、240μg/mL)组,考察药物对斑马鱼早期发育毒性的影响;采用试剂盒测定各组幼鱼组织的糖含量;采用茜素红染色法考察各组斑马鱼头骨矿化面积和骨密度;采用qRT-PCR法检测各组斑马鱼骨质疏松相关基因Runx家族转录因子2b(Runx family transcription factor 2b,Runx2b)、Sp7转录因子(Sp7 transcription factor,Sp7)、I型胶原蛋白α2(collagen type Iα2,col1a2)、富含半胱氨酸的酸性分泌蛋白质因子(cysteine-rich acidic secreted protein,sparc)和维生素D受体b(vitamin D receptor b,vdrb)mRNA表达情况。结果显微注射链脲佐菌素和浸泡泼尼松龙能够提高幼鱼组织糖浓度,降低头骨矿化面积和骨密度。与模型组比较,多花黄精多糖显著上调斑马鱼幼鱼2型糖尿病合并骨质疏松症模型Runx2b、Sp7、vdrb、sparc、col1a2mRNA表达水平(P<0.05、0.01、0.001)。结论多花黄精多糖对斑马鱼幼鱼2型糖尿病合并骨质疏松症模型有较好的降血糖及抗骨质疏松症作用。
